His primary scientific interests are in Matrix metalloproteinase, Immunology, Macrophage, Inflammation and Macrophage elastase. His studies deal with areas such as Molecular biology, Extracellular matrix, In situ hybridization and In vivo as well as Matrix metalloproteinase. His Immunology study integrates concerns from other disciplines, such as Cancer, Cancer research and Signal transduction, Cell biology.
His Macrophage research includes themes of Bronchoalveolar lavage, Lung and Monocyte. His Inflammation research integrates issues from Proteases and Cytokine. His Macrophage elastase research includes elements of Elastase and Pathology.
Steven D. Shapiro spends much of his time researching Immunology, Matrix metalloproteinase, Pathology, Lung and COPD. His work deals with themes such as Bronchoalveolar lavage, Macrophage and Cancer research, which intersect with Immunology. His Matrix metalloproteinase research is multidisciplinary, relying on both Molecular biology, Extracellular matrix, Cell biology and Macrophage elastase.
Steven D. Shapiro specializes in Lung, namely Lung injury. The various areas that Steven D. Shapiro examines in his COPD study include Pulmonary disease, Disease and Pathogenesis. His Inflammation research is included under the broader classification of Internal medicine.
Immunology, COPD, Cancer research, Internal medicine and Lung cancer are his primary areas of study. His Immunology research includes elements of Receptor, Peroxisome proliferator-activated receptor and Bronchoalveolar lavage, Lung. His research in Receptor focuses on subjects like Lung structure, which are connected to Pathology.
Steven D. Shapiro has included themes like Genetics, Anesthesia, Disease and Candidate gene in his COPD study. His Cancer research research integrates issues from Cell, DNA methylation, Inflammation, Cancer cell and Immune system. His studies deal with areas such as Endocrinology, Oncology and Cardiology as well as Internal medicine.
Steven D. Shapiro mainly investigates Immunology, COPD, Lung, Cancer research and Candidate gene. His Immunology research is multidisciplinary, incorporating perspectives in Reverse transcription polymerase chain reaction, Cell culture, Epithelium, NFKB1 and Signal transduction. His work carried out in the field of COPD brings together such families of science as Apoptosis, Peroxisome proliferator-activated receptor, Chemokine, Rosiglitazone and Bronchoalveolar lavage.
The concepts of his Lung study are interwoven with issues in Autophagy, TFEB and Lung cancer. Steven D. Shapiro combines subjects such as Proteostasis, Genetic enhancement and Respiratory system with his study of Cancer research. His research in Annexin intersects with topics in Inflammation and Macrophage.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice
R. Dean Hautamaki;Dale K. Kobayashi;Robert M. Senior;Steven D. Shapiro.
Science (1997)
MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes
Thiennu H Vu;J.Michael Shipley;Gabriele Bergers;Joel E Berger.
Cell (1998)
A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation
Marin H. Kollef;Steven D. Shapiro;Patricia Silver;Robert E. St. John.
Critical Care Medicine (1997)
Matrix metalloproteinase degradation of extracellular matrix: biological consequences
Steven D Shapiro.
Current Opinion in Cell Biology (1998)
Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms
Robert Pyo;Jason K. Lee;J. Michael Shipley;John A. Curci.
Journal of Clinical Investigation (2000)
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase– and cathepsin-dependent emphysema
Tao Zheng;Zhou Zhu;Zhongde Wang;Robert J. Homer;Robert J. Homer.
Journal of Clinical Investigation (2000)
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis.
Abderrazzaq Belaaouaj;Ronald McCarthy;Mary Baumann;Zhimin Gao.
Nature Medicine (1998)
Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of D-aspartate and nuclear weapons-related radiocarbon.
S D Shapiro;S K Endicott;M A Province;J A Pierce.
Journal of Clinical Investigation (1991)
Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice
J M Shipley;R L Wesselschmidt;D K Kobayashi;T J Ley.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice.
Steven D. Shapiro;Nir M. Goldstein;A. McGarry Houghton;A. McGarry Houghton;Dale K. Kobayashi.
American Journal of Pathology (2003)
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