Howard G. Welgus

Research.com Recognitions

• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

  Brian K. Pilcher;Jo Ann Dumin;Barry D. Sudbeck;Stephen M. Krane

  859
  Citations

• Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.

  William P. Arend;Howard G. Welgus;Robert C. Thompson;Stephen P. Eisenberg

  783
  Citations

• Human 92- and 72-kilodalton type IV collagenases are elastases.

  R. M. Senior;G. L. Griffin;C. J. Fliszar;S. D. Shapiro

  674
  Citations

• Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

  H G Welgus;E J Campbell;J D Cury;A Z Eisen

  633
  Citations

• IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes.

  S Lacraz;L P Nicod;R Chicheportiche;H G Welgus

  588
  Citations

• Matrix Metalloproteinases Generate Angiostatin: Effects on Neovascularization

  Lynn A. Cornelius;Leslie C. Nehring;Elizabeth Harding;Mark Bolanowski

  587
  Citations

• Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.

  R. W. Thompson;D. R. Holmes;R. A. Mertens;Shixiong Liao

  553
  Citations

• Interstitial Collagenase (MMP-1) Expression in Human Carotid Atherosclerosis

  Seppo T. Nikkari;Kevin D. O’Brien;Marina Ferguson;Thomas Hatsukami

  532
  Citations

• The collagen substrate specificity of human skin fibroblast collagenase.

  H G Welgus;J J Jeffrey;A Z Eisen

  513
  Citations

• Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme.

  Igor Halpert;Ulrike I. Sires;Jill D. Roby;Susan Potter-Perigo

  506
  Citations

• Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing.

  U K Saarialho-Kere;S O Kovacs;A P Pentland;J E Olerud

  442
  Citations

• The collagen substrate specificity of human neutrophil collagenase

  K A Hasty;J J Jeffrey;M S Hibbs;H G Welgus

  402
  Citations

• Matrilysin expression and function in airway epithelium.

  Sarah E. Dunsmore;Ulpu K. Saarialho-Kere;Jill D. Roby;Carole L. Wilson

  401
  Citations

• Primary structure and cDNA cloning of human fibroblast collagenase inhibitor.

  David F. Carmichael;Andreas Sommer;Robert C. Thompson;David C. Anderson

  384
  Citations

• Matrix Metalloproteinase Gelatinase B (MMP-9) Coordinates and Effects Epithelial Regeneration

  Royce Mohan;Shravan K. Chintala;Jae Chang Jung;Winston V.L. Villar

  359
  Citations

• Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds.

  U K Saarialho-Kere;A P Pentland;H Birkedal-Hansen;W C Parks

  348
  Citations

• The Structural Basis for the Elastolytic Activity of the 92-kDa and 72-kDa Gelatinases ROLE OF THE FIBRONECTIN TYPE II-LIKE REPEATS

  J. Michael Shipley;Glenn A R Doyle;Catherine J. Fliszar;Qi Zhuang Ye

  312
  Citations

• Initiation of Osteoclast Bone Resorption by Interstitial Collagenase

  L S Holliday;H G Welgus;C J Fliszar;G M Veith

  303
  Citations

• Human Alveolar Macrophages Produce a Fibroblast-like Collagenase and Collagenase Inhibitor

  H.G. Welgus;E.J. Campbell;Z. Bar-Shavit;R.M. Senior

  292
  Citations

• Elastin Degradation by Matrix Metalloproteinases CLEAVAGE SITE SPECIFICITY AND MECHANISMS OF ELASTOLYSIS

  Robert P. Mecham;Thomas J. Broekelmann;Catherine J. Fliszar;Steven D. Shapiro

  276
  Citations