William C. Parks

Research.com Recognitions

• 1934 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1915 - Fellow of the Royal Society of Canada

Overview

Best Publications

• Matrix metalloproteinases as modulators of inflammation and innate immunity

  William C. Parks;William C. Parks;Carole L. Wilson;Yolanda S. López-Boado

  2600
  Citations

• Induction and Evasion of Host Defenses by Type 1-Piliated Uropathogenic Escherichia Coli

  M.A. Mulvey;Y.S. Lopez-Boado;C.L. Wilson;R. Roth

  1597
  Citations

• Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.

  Tokiyoshi Ayabe;Donald P. Satchell;Carole L. Wilson;William C. Parks

  1450
  Citations

• Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense

  Carole L. Wilson;Andre J. Ouellette;Donald P. Satchell;Tokiyoshi Ayabe

  1269
  Citations

• Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

  Qinglang Li;Pyong Woo Park;Carole L. Wilson;William C. Parks

  1086
  Citations

• Metalloproteinases and their inhibitors: regulators of wound healing.

  Sean E. Gill;William C. Parks

  950
  Citations

• The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

  Brian K. Pilcher;Jo Ann Dumin;Barry D. Sudbeck;Stephen M. Krane

  859
  Citations

• Control of matrix metalloproteinase catalytic activity.

  Hyun-Jeong Ra;William C. Parks

  788
  Citations

• Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase.

  Xiaoyun Fu;Sean Y. Kassim;William C. Parks;Jay W. Heinecke

  664
  Citations

• Diverse functions of matrix metalloproteinases during fibrosis.

  Matthew Giannandrea;William C. Parks;William C. Parks

  586
  Citations

• Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.

  R. W. Thompson;D. R. Holmes;R. A. Mertens;Shixiong Liao

  553
  Citations

• Matrix metalloproteinases in lung biology

  William C Parks;Steven D Shapiro

  531
  Citations

• Mechanisms of tendon injury and repair.

  Stavros Thomopoulos;William C. Parks;Daniel B. Rifkin;Kathleen A. Derwin

  521
  Citations

• Matrix metalloproteinases in repair.

  William C. Parks

  518
  Citations

• Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme.

  Igor Halpert;Ulrike I. Sires;Jill D. Roby;Susan Potter-Perigo

  506
  Citations

• PDGF A-chain gene is expressed by mammalian neurons during development and in maturity.

  Hsiu Jeng Yeh;Kenneth G. Ruit;Ya Xian Wang;Ya Xian Wang;William C. Parks

  485
  Citations

• Matrix Metalloproteinases (MMPs) and Their Physiological Inhibitors (TIMPs) Are Differentially Expressed during Excisional Skin Wound Repair

  Marianne Madlener;William C. Parks;Sabine Werner

  479
  Citations

• Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: Preservation of aortic elastin associated with suppressed production of 92 kD gelatinase

  Drazen Petrinec;Shixiong Liao;Dennis R. Holmes;Jeffrey M. Reilly

  458
  Citations

• Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium.

  John K. McGuire;John K. McGuire;Qinglang Li;William C. Parks

  444
  Citations

• Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing.

  U K Saarialho-Kere;S O Kovacs;A P Pentland;J E Olerud

  442
  Citations