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D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
17772
World Ranking
8570
National Ranking
3850

Overview

Jerome S. Pinkner is affiliated with Washington University in St. Louis in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to Epidemiology, Endocrinology, Molecular Biology, Surgery, and Molecular Medicine.

The scientist's research focuses extensively on urinary tract infections (UTIs), with a strong emphasis on management and pathogenesis. They have explored studies related to Escherichia coli, gut microbiota and health, antibiotic resistance in bacteria, antimicrobial resistance in Staphylococcus, pelvic floor disorders treatments, and bladder and urothelial cancer treatments.

Frequent co-authors of Jerome S. Pinkner include:

  • Scott J. Hultgren
  • Karen Dodson
  • Chloe L. P. Obernuefemann
  • Andrew L. Kau
  • Kevin O. Tamadonfar

They have published a number of papers recently, including:

  • "Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women" (2022, Nature Microbiology)
  • "Microbial co-occurrences on catheters from long-term catheterized patients" (2024, Nature Communications)
  • "A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis" (2021, PLoS Pathogens)
  • "Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections" (2023, Proceedings of the National Academy of Sciences)
  • "Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics" (2022, Proceedings of the National Academy of Sciences)

The venues where Jerome S. Pinkner frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Science Advances
  • Nature Communications
  • Nature Microbiology

Best Publications

  • Role of Escherichia coli Curli Operons in Directing Amyloid Fiber Formation

    Matthew R. Chapman;Lloyd S. Robinson;Jerome S. Pinkner;Robyn Roth

  • Type 1 pilus‐mediated bacterial invasion of bladder epithelial cells

    Juan J. Martinez;Matthew A. Mulvey;Joel D. Schilling;Jerome S. Pinkner

  • X-ray Structure of the FimC-FimH Chaperone-Adhesin Complex from Uropathogenic Escherichia coli

    Devapriya Choudhury;Andrew Thompson;Vivian Stojanoff;Solomon Langermann

  • Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination.

    Solomon Langermann;Solomon Langermann;Susan Palaszynski;Susan Palaszynski;Michelle Barnhart;Michelle Barnhart;Gale Auguste;Gale Auguste

  • FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae.

    C H Jones;J S Pinkner;R Roth;J Heuser

  • Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin

    Julie Bouckaert;Jenny Berglund;Mark Schembri;Erwin De Genst

  • Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection

    Chia-Suei Hung;Julie Bouckaert;Julie Bouckaert;Danielle Hung;Jerome Pinkner

  • Structural Basis of Chaperone Function and Pilus Biogenesis

    Frederic G. Sauer;Klaus Fütterer;Jerome S. Pinkner;Karen W. Dodson

  • Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

    Lynette Cegelski;Jerome S Pinkner;Neal D Hammer;Corinne K Cusumano

  • Vaccination with FimH adhesin protects cynomolgus monkeys from colonization and infection by uropathogenic Escherichia coli.

    Solomon Langermann;Roland Möllby;Jeanne E. Burlein;Susan R. Palaszynski

  • Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria

    Jerome S. Pinkner;Han Remaut;Floris Buelens;Eric Miller

  • The chaperone-assisted membrane release and folding pathway is sensed by two signal transduction systems.

    C. Hal Jones;Paul N. Danese;Jerome S. Pinkner;Thomas Joseph Silhavy

  • Treatment and Prevention of Urinary Tract Infection with Orally Active FimH Inhibitors

    Corinne K. Cusumano;Jerome S. Pinkner;Zhenfu Han;Sarah E. Greene

  • Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

    Parveen Goyal;Petya V. Krasteva;Nani Van Gerven;Francesca Gubellini

  • Structure-based drug design and optimization of mannoside bacterial FimH antagonists.

    Zhenfu Han;Jerome S. Pinkner;Bradley Ford;Robert Obermann

  • Chaperone Priming of Pilus Subunits Facilitates a Topological Transition that Drives Fiber Formation

    Frederic G. Sauer;Jerome S. Pinkner;Gabriel Waksman;Gabriel Waksman;Gabriel Waksman;Scott J. Hultgren

  • Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

    Caitlin N. Spaulding;Roger D. Klein;Ségolène Ruer;Andrew L. Kau

  • Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor.

    Karen W. Dodson;Jerome S. Pinkner;Thierry Rose;Goran Magnusson

  • Fiber formation across the bacterial outer membrane by the chaperone/usher pathway.

    Han Remaut;Chunyan Tang;Nadine S. Henderson;Jerome S. Pinkner

  • Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli.

    Jeffrey P. Henderson;Jan R. Crowley;Jerome S. Pinkner;Jennifer N. Walker

Frequent Co-Authors

Scott J. Hultgren
Scott J. Hultgren Washington University in St. Louis
Gabriel Waksman
Gabriel Waksman University College London
Michael G. Caparon
Michael G. Caparon Washington University in St. Louis
Jan Kihlberg
Jan Kihlberg Uppsala University
Carl Frieden
Carl Frieden Washington University in St. Louis
Staffan Normark
Staffan Normark Karolinska Institute
Huilin Li
Huilin Li Van Andel Institute
Gabor Tigyi
Gabor Tigyi University of Tennessee Health Science Center
Birgitta Henriques-Normark
Birgitta Henriques-Normark Karolinska Institute
Thomas J. Silhavy
Thomas J. Silhavy Princeton University

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