World's Best Scientists 2026 revealed!
Rudi Glockshuber

Rudi Glockshuber

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
19453
World Ranking
5331
National Ranking
105

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2003 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics

Overview

Rudi Glockshuber is affiliated with ETH Zurich in Switzerland and focuses their research primarily within the field of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields including Molecular Biology, Materials Chemistry, Spectroscopy, Ecology, and Cell Biology.

The main topics that characterize Glockshuber's research include:

  • Enzyme Structure and Function
  • Bacteriophages and microbial interactions
  • Glycosylation and Glycoproteins Research
  • Molecular spectroscopy and chirality
  • Protein Structure and Dynamics
  • Biochemical and Structural Characterization
  • Endoplasmic Reticulum Stress and Disease

The scientist has published extensively in a range of reputable journals. Frequent publication venues for Glockshuber include:

  • Nature Communications
  • Science Advances
  • Angewandte Chemie International Edition
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Angewandte Chemie

Recent significant papers by Glockshuber and collaborators highlight a focus on protein structures and interactions:

  • Architecture and function of human uromodulin filaments in urinary tract infections, 2020, published in Science
  • The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism, 2020, published in eLife
  • Glycan-protein interactions determine kinetics of N-glycan remodeling, 2021, published in RSC Chemical Biology
  • Structure of native glycolipoprotein filaments in honeybee royal jelly, 2020, published in Nature Communications
  • A metabolite binding protein moonlights as a bile-responsive chaperone, 2020, published in The EMBO Journal

Throughout their career, Glockshuber has collaborated frequently with several researchers, including Christoph Giese, Daniel Boehringer, Dawid Zyla, Rafal Zdanowicz, and Pavel Afanasyev.

Glockshuber received recognition from the German National Academy of Sciences Leopoldina in 2003 in the area of Biochemistry and Biophysics.

Best Publications

  • NMR structure of the mouse prion protein domain PrP(121–231)

    Roland Riek;Simone Hornemann;Gerhard Wider;Martin Billeter

  • NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

    Roland Riek;Simone Hornemann;Gerhard Wider;Rudi Glockshuber

  • Prion (PrPSc)-specific epitope defined by a monoclonal antibody.

    Carsten Korth;Beat Stierli;Peter Streit;Markus Moser

  • A comparison of strategies to stabilize immunoglobulin Fv-fragments.

    Rudi Glockshuber;Mark Malia;Ilse Pfitzinger;Andreas Plueckthun

  • Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: evidence from in vitro FimH binding.

    Ge Zhou;Wen-Jun Mo;Peter Sebbel;Guangwei Min

  • Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein.

    Susanne Liemann;Rudi Glockshuber

  • Amyloid-beta aggregation.

    Verena H. Finder;Rudi Glockshuber

  • The structure of a cytolytic alpha-helical toxin pore reveals its assembly mechanism.

    Marcus Mueller;Ulla Grauschopf;Ulla Grauschopf;Timm Maier;Rudi Glockshuber

  • Redox properties of protein disulfide isomerase (DsbA) from Escherichia coli.

    Martina Wunderlich;Rudi Glockshuber

  • A scrapie-like unfolding intermediate of the prion protein domain PrP(121-231) induced by acidic pH

    Simone Hornemann;Rudi Glockshuber

  • Prion protein NMR structure and familial human spongiform encephalopathies

    Roland Riek;Gerhard Wider;Martin Billeter;Simone Hornemann

  • Atomic-resolution three-dimensional structure of amyloid β fibrils bearing the Osaka mutation.

    Anne K Schütz;Toni Vagt;Matthias Huber;Oxana Y Ovchinnikova

  • Exploring the 3D Molecular Architecture of Escherichia coli Type 1 Pili

    Erik Hahn;Peter Wild;Uta Hermanns;Peter Sebbel

  • A single dipeptide sequence modulates the redox properties of a whole enzyme family

    Martina Huber-Wunderlich;Rudi Glockshuber

  • The disulfide bonds in antibody variable domains: effects on stability, folding in vitro, and functional expression in Escherichia coli.

    Glockshuber R;Schmidt T;Plückthun A

  • Recombinant full-length murine prion protein, mPrP(23–231): purification and spectroscopic characterization

    Simone Hornemann;Carsten Korth;Bruno Oesch;Roland Riek

  • Oligosaccharyltransferase: the central enzyme of N-linked protein glycosylation

    Elisabeth Mohorko;Rudi Glockshuber;Markus Aebi

  • ERp57 is a multifunctional thiol-disulfide oxidoreductase.

    Eva Maria Frickel;Patrick Frei;Marlène Bouvier;Walter F. Stafford

  • Characterization of Escherichia coli thioredoxin variants mimicking the active-sites of other thiol/disulfide oxidoreductases

    Ekkehard Mössner;Martina Huber-Wunderlich;Rudi Glockshuber

  • Prion protein expression in different species: Analysis with a panel of new mAbs

    Gianluigi Zanusso;Dacai Liu;Sergio Ferrari;Ivan Hegyi

Frequent Co-Authors

Kurt Wüthrich
Kurt Wüthrich ETH Zurich
Markus G. Grütter
Markus G. Grütter University of Zurich
Roland Riek
Roland Riek ETH Zurich
Martin Billeter
Martin Billeter University of Gothenburg
Hauke Hennecke
Hauke Hennecke ETH Zurich
Andreas Plückthun
Andreas Plückthun University of Zurich
Rainer Jaenicke
Rainer Jaenicke University of Regensburg
Klaus Maskos
Klaus Maskos Proteros biostructures GmbH
Markus Aebi
Markus Aebi ETH Zurich
Olivier Devuyst
Olivier Devuyst University of Zurich

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