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Markus Aebi

Markus Aebi

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
34534
World Ranking
2410
National Ranking
52

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Markus Aebi is affiliated with ETH Zurich in Switzerland and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research spans across several subfields, including Molecular Biology, Organic Chemistry, Immunology, Cell Biology, and Materials Chemistry.

The scientist's work prominently focuses on areas such as Glycosylation and Glycoproteins Research, Carbohydrate Chemistry and Synthesis, Galectins and Cancer Biology, Enzyme Structure and Function, Protein Structure and Dynamics, Endoplasmic Reticulum Stress and Disease, and Cellular transport and secretion.

Markus Aebi has contributed to various scientific journals, with frequent publications in Glycobiology and bioRxiv (Cold Spring Harbor Laboratory). Other venues include Science, Nature, and RSC Chemical Biology.

  • Architecture and function of human uromodulin filaments in urinary tract infections (2020, Science)
  • Structure and mechanism of the ER-based glucosyltransferase ALG6 (2020, Nature)
  • Glycan-protein interactions determine kinetics of N-glycan remodeling (2021, RSC Chemical Biology)
  • Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase (2022, Nature Communications)
  • N-Glycosylation Enhances Conformational Flexibility of Protein Disulfide Isomerase Revealed by Microsecond Molecular Dynamics and Markov State Modeling (2021, The Journal of Physical Chemistry B)

Frequent co-authors in Markus Aebi's work include Chia-Wei Lin, Marie-Estelle Losfeld, Kaspar P. Locher, Rossitza N. Irobalieva, and Rudi Glockshuber.

Best Publications

  • Essentials of Glycobiology [Internet]

    Ajit Varki;Richard D Cummings;Jeffrey D Esko;Pamela Stanley

  • Roles of N-Linked Glycans in the Endoplasmic Reticulum

    Ari Helenius;Markus Aebi

  • Symbol Nomenclature for Graphical Representations of Glycans.

    Ajit Varki;Richard D. Cummings;Markus Aebi;Nicole H. Packer

  • N-Linked Glycosylation in Campylobacter jejuni and Its Functional Transfer into E. coli

    Michael Wacker;Dennis Linton;Paul G. Hitchen;Mihai Nita-Lazar

  • The dolichol pathway of N-linked glycosylation

    Patricie Burda;Markus Aebi

  • N-linked protein glycosylation in the ER.

    Markus Aebi

  • Mechanisms and principles of N-linked protein glycosylation.

    Flavio Schwarz;Markus Aebi

  • N-glycan structures: recognition and processing in the ER

    Markus Aebi;Riccardo Bernasconi;Simone Clerc;Maurizio Molinari

  • Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli.

    Mario F. Feldman;Michael Wacker;Marcela Hernandez;Paul G. Hitchen

  • Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific Oligosaccharide Structure

    Claude A. Jakob;Patricie Burda;Jürgen Roth;Markus Aebi

  • X-ray structure of a bacterial oligosaccharyltransferase

    Christian Lizak;Sabina Gerber;Shin Numao;Shin Numao;Markus Aebi

  • Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA.

    M. Aebi;H. Hornig;R.A. Padgett;J. Reiser

  • Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments

    Chih-Yen King;Peter Tittmann;Heinz Gross;Roland Gebert

  • Updates to the Symbol Nomenclature for Glycans guidelines.

    Sriram Neelamegham;Kiyoko Aoki-Kinoshita;Evan Bolton;Martin Frank

  • Definition of the bacterial N-glycosylation site consensus sequence.

    Michael Kowarik;N Martin Young;Shin Numao;Benjamin L Schulz

  • The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay is a fast and reliable method for colorimetric determination of fungal cell densities.

    Florian M. Freimoser;Claude A. Jakob;Markus Aebi;Urs Tuor

  • Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

    Simone Clerc;Christian Hirsch;Daniela Maria Oggier;Paola Deprez

  • Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein.

    Jonne Helenius;Davis T W Ng;Cristina L Marolda;Peter Walter

  • High-dimensional and large-scale phenotyping of yeast mutants

    Yoshikazu Ohya;Jim Sese;Masashi Yukawa;Fumi Sano

  • N-linked protein glycosylation in the endoplasmic reticulum.

    Jörg Breitling;Markus Aebi

Frequent Co-Authors

Ursula Kües
Ursula Kües University of Göttingen
Eric G. Berger
Eric G. Berger University of Zurich
Thierry Hennet
Thierry Hennet University of Zurich
Jean-Louis Reymond
Jean-Louis Reymond University of Bern
Gert Matthijs
Gert Matthijs KU Leuven
Miguel A. Valvano
Miguel A. Valvano Queen's University Belfast
Tamis Darbre
Tamis Darbre University of Bern
Benjamin L. Schulz
Benjamin L. Schulz University of Queensland
Iain B. H. Wilson
Iain B. H. Wilson BOKU University

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