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Jean-Louis Reymond

Jean-Louis Reymond

D-Index & Metrics

Chemistry

D-Index
84
Citations
27715
World Ranking
2792
National Ranking
68

Overview

Jean-Louis Reymond is affiliated with the University of Bern in Switzerland. Their research spans broadly within Biochemistry, Genetics and Molecular Biology, with a particular emphasis on the subfields of Molecular Biology, Computational Theory and Mathematics, Materials Chemistry, Microbiology, and Organic Chemistry.

The scientist's publication record includes contributions across several topics, notably:

  • Computational Drug Discovery Methods
  • Chemical Synthesis and Analysis
  • Antimicrobial Peptides and Activities
  • Dendrimers and Hyperbranched Polymers
  • Machine Learning in Materials Science
  • Machine Learning in Bioinformatics
  • RNA Interference and Gene Delivery

Jean-Louis Reymond has extensive collaborations with frequent co-authors such as Sacha Javor, Thilo Köhler, Christian van Delden, Hippolyte Personne, and Markus Orsi, reflecting a multidisciplinary approach to their research endeavors.

Regular publication venues demonstrate the diverse dissemination of their work and include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • CHIMIA International Journal for Chemistry
  • The Cambridge Structural Database
  • Journal of Cheminformatics
  • Chemical Science

Among recent scholarly contributions are several notable papers, including:

  • One molecular fingerprint to rule them all: drugs, biomolecules, and the metabolome (2020, Journal of Cheminformatics)
  • AiZynthFinder: a fast, robust and flexible open-source software for retrosynthetic planning (2020, Journal of Cheminformatics)
  • Visualization of very large high-dimensional data sets as minimum spanning trees (2020, Journal of Cheminformatics)
  • Mapping the space of chemical reactions using attention-based neural networks (2021, Nature Machine Intelligence)
  • Extraction of organic chemistry grammar from unsupervised learning of chemical reactions (2021, Science Advances)

The body of work of Jean-Louis Reymond reflects a consistent focus on the integration of computational methods and chemical sciences, combining data-driven approaches with experimental frameworks in drug discovery, synthesis, and analysis.

Best Publications

  • Enumeration of 166 Billion Organic Small Molecules in the Chemical Universe Database GDB-17

    Lars Ruddigkeit;Ruud van Deursen;Lorenz C. Blum;Jean-Louis Reymond

  • An efficient one-step site-directed and site-saturation mutagenesis protocol

    Lei Zheng;Ulrich Baumann;Jean Louis Reymond

  • 970 million druglike small molecules for virtual screening in the chemical universe database GDB-13.

    Lorenz C. Blum;Jean-Louis Reymond

  • The chemical space project.

    Jean-Louis Reymond

  • Multivalent glycoconjugates as anti-pathogenic agents

    Anna Bernardi;Jesus Jimenez-Barbero;Alessandro Casnati;Christina De Castro

  • Virtual exploration of the chemical universe up to 11 atoms of C, N, O, F: assembly of 26.4 million structures (110.9 million stereoisomers) and analysis for new ring systems, stereochemistry, physicochemical properties, compound classes, and drug discovery.

    Tobias Fink;Jean-Louis Reymond

  • Virtual Exploration of the Small-Molecule Chemical Universe below 160 Daltons†

    Tobias Fink;Heinz Bruggesser;Jean-Louis Reymond

  • Chemical space as a source for new drugs

    Jean-Louis Reymond;Ruud van Deursen;Lorenz C. Blum;Lars Ruddigkeit

  • Exploring chemical space for drug discovery using the chemical universe database.

    Jean-Louis Reymond;Mahendra Awale

  • One molecular fingerprint to rule them all: drugs, biomolecules, and the metabolome

    Alice Capecchi;Daniel Probst;Jean-Louis Reymond

  • Randomized SMILES strings improve the quality of molecular generative models

    Josep Arús-Pous;Josep Arús-Pous;Simon Viet Johansson;Oleksii Prykhodko;Esben Jannik Bjerrum

  • Enzyme assays for high-throughput screening.

    Jean-Philippe Goddard;Jean-Louis Reymond

  • Inhibition and Dispersion of Pseudomonas aeruginosa Biofilms by Glycopeptide Dendrimers Targeting the Fucose-Specific Lectin LecB

    Emma M.V. Johansson;Shanika A. Crusz;Elena Kolomiets;Lieven Buts

  • AiZynthFinder: a fast, robust and flexible open-source software for retrosynthetic planning

    Samuel Genheden;Amol Thakkar;Amol Thakkar;Veronika Chadimová;Jean-Louis Reymond

  • Mapping the space of chemical reactions using attention-based neural networks

    Philippe Schwaller;Philippe Schwaller;Daniel Probst;Alain C. Vaucher;Vishnu H. Nair

  • Visualization of very large high-dimensional data sets as minimum spanning trees.

    Daniel Probst;Jean-Louis Reymond

  • Peptide dendrimers as artificial enzymes, receptors, and drug-delivery agents.

    Tamis Darbre;Jean-Louis Reymond

  • Extraction of organic chemistry grammar from unsupervised learning of chemical reactions.

    Philippe Schwaller;Philippe Schwaller;Benjamin Hoover;Jean-Louis Reymond;Hendrik Strobelt

  • Recent advances in enzyme assays

    Jean-Philippe Goddard;Jean-Louis Reymond

  • Novel methods for biocatalyst screening.

    Denis Wahler;Jean Louis Reymond

  • Isolation and biochemical characterization of two novel metagenome-derived esterases.

    C Elend;C Schmeisser;C Leggewie;Peter Babiak

  • Structure and mechanism of an active lipid-linked oligosaccharide flippase.

    Camilo Perez;Sabina Gerber;Jérémy Boilevin;Monika Bucher

  • A fluorescent metal sensor based on macrocyclic chelation

    Gérard Klein;Daniel Kaufmann;Stefan Schürch;Jean-Louis Reymond

Frequent Co-Authors

Tamis Darbre
Tamis Darbre University of Bern
Richard A. Lerner
Richard A. Lerner Scripps Research Institute
Pierre Vogel
Pierre Vogel École Polytechnique Fédérale de Lausanne
Thilo Köhler
Thilo Köhler University of Geneva
Ehud Keinan
Ehud Keinan Technion – Israel Institute of Technology
Ola Engkvist
Ola Engkvist AstraZeneca (United Kingdom)
Matthias A. Hediger
Matthias A. Hediger University of Bern
Markus Aebi
Markus Aebi ETH Zurich
Daniel Bertrand
Daniel Bertrand University of Geneva
Sonia Bertrand
Sonia Bertrand University of Geneva

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