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Microbiology

D-Index
54
Citations
12979
World Ranking
3925
National Ranking
94

Overview

Thilo Köhler is affiliated with the University of Geneva in Switzerland and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research encompasses molecular biology, microbiology, pharmacology, molecular medicine, and ecology.

The scientist's work spans various topics, including:

  • Antimicrobial Peptides and Activities
  • Chemical Synthesis and Analysis
  • Antibiotic Resistance in Bacteria
  • Bacteriophages and microbial interactions
  • Machine Learning in Bioinformatics
  • Bacterial biofilms and quorum sensing
  • Microbial Natural Products and Biosynthesis

Köhler has published research in multiple venues, with frequent publications in:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Planta Medica
  • Nature Communications
  • Frontiers in Microbiology
  • Molecules

Some of the recent papers authored or co-authored by Köhler include:

  • "Machine learning designs non-hemolytic antimicrobial peptides" (2021) published in Chemical Science
  • "Susceptibility profiles and resistance genomics of Pseudomonas aeruginosa isolates from European ICUs participating in the ASPIRE-ICU trial" (2022) published in Journal of Antimicrobial Chemotherapy
  • "Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa" (2023) published in Nature Communications
  • "Adaptive and Mutational Responses to Peptide Dendrimer Antimicrobials in Pseudomonas aeruginosa" (2020) published in Antimicrobial Agents and Chemotherapy
  • "Stereorandomization as a Method to Probe Peptide Bioactivity" (2021) published in ACS Central Science

Köhler collaborates frequently with multiple researchers, including:

  • Christian van Delden
  • Alexandre Lüscher
  • Jean-Louis Reymond
  • Sacha Javor
  • Xingguang Cai

Best Publications

  • Swarming of Pseudomonas aeruginosa Is Dependent on Cell-to-Cell Signaling and Requires Flagella and Pili

    Thilo Köhler;Lasta Kocjancic Curty;Francisco Barja;Christian van Delden

  • Characterization of MexE–MexF–OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa

    Thilo Kohler;Mehri Michea-Hamzehpour;Uta Henze;Naomasa Gotoh

  • Azithromycin Inhibits Quorum Sensing in Pseudomonas aeruginosa

    Kazuhiro Tateda;Rachel Comte;Jean-Claude Pechere;Thilo Köhler

  • Involvement of an Active Efflux System in the Natural Resistance of Pseudomonas aeruginosa to Aminoglycosides

    Julio Ramos Aires;Thilo Köhler;Hiroshi Nikaido;Patrick Plésiat

  • CzcR-CzcS, a two-component system involved in heavy metal and carbapenem resistance in Pseudomonas aeruginosa.

    Karl Perron;Olivier Caille;Claude Rossier;Christian van Delden

  • Characterization of MexT, the Regulator of the MexE-MexF-OprN Multidrug Efflux System of Pseudomonas aeruginosa

    Thilo Köhler;Simone F. Epp;Lasta Kocjancic Curty;Jean-Claude Pechère

  • Overexpression of the MexEF-OprN Multidrug Efflux System Affects Cell-to-Cell Signaling in Pseudomonas aeruginosa

    Thilo Köhler;Christian van Delden;Lasta Kocjancic Curty;Mehri Michea Hamzehpour

  • Population structure of Pseudomonas aeruginosa

    Lutz Wiehlmann;Gerd Wagner;Nina Cramer;Benny Siebert

  • In Vivo Emergence of Multidrug-Resistant Mutants of Pseudomonas aeruginosa Overexpressing the Active Efflux System MexA-MexB-OprM

    Isabelle Ziha-Zarifi;Catherine Llanes;Thilo Köhler;Jean-Claude Pechere

  • Carbapenem Activities against Pseudomonas aeruginosa: Respective Contributions of OprD and Efflux Systems

    Thilo Köhler;Mehri Michea-Hamzehpour;Simone F. Epp;Jean Claude Pechere

  • Pseudomonas aeruginosa virulence analyzed in a Dictyostelium discoideum host system

    Pierre Cosson;Laurence Zulianello;Olivier Join-Lambert;François Faurisson

  • Siderophores as drug delivery agents: application of the "Trojan Horse" strategy.

    Ute Möllmann;Lothar Heinisch;Adolf Bauernfeind;Thilo Köhler

  • Rhamnolipids Are Virulence Factors That Promote Early Infiltration of Primary Human Airway Epithelia by Pseudomonas aeruginosa

    Laurence Zulianello;Coralie Canard;Thilo Köhler;Dorothée Caille

  • Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR

    Jean-Luc Claude Dumas;Christian van Delden;Karl Perron;Thilo Kohler

  • Biofilm formation by Pseudomonas aeruginosa: role of the C4-HSL cell-to-cell signal and inhibition by azithromycin

    Sabine Adelaide Eugenie Favre-Bonte;Thilo Kohler;Christian van Delden

  • Differential selection of multidrug efflux systems by quinolones in Pseudomonas aeruginosa

    T Köhler;M Michea-Hamzehpour;P Plesiat;A L Kahr

  • Cooperation and virulence of clinical Pseudomonas aeruginosa populations.

    Thilo Köhler;Angus Buckling;Christian van Delden

  • Quorum sensing inhibition selects for virulence and cooperation in Pseudomonas aeruginosa.

    Thilo Köhler;Gabriel G. Perron;Angus Buckling;Christian van Delden

  • Multidrug efflux in intrinsic resistance to trimethoprim and sulfamethoxazole in Pseudomonas aeruginosa.

    Thilo Kohler;Menno Kok;Mehri Michea-Hamzehpour;Patrick Plesiat

  • Involvement of Pseudomonas putida RpoN sigma factor in regulation of various metabolic functions.

    T Köhler;S Harayama;J L Ramos;K N Timmis

Frequent Co-Authors

Christian van Delden
Christian van Delden University of Geneva
Jean-Claude Pechère
Jean-Claude Pechère University of Geneva
Jean-Louis Reymond
Jean-Louis Reymond University of Bern
Patrick Plésiat
Patrick Plésiat University of Franche-Comté
Pierre Cosson
Pierre Cosson University of Geneva
Malcolm G. P. Page
Malcolm G. P. Page Jacobs University
Tamis Darbre
Tamis Darbre University of Bern
Angus Buckling
Angus Buckling University of Exeter
Shigeaki Harayama
Shigeaki Harayama Chuo University
Jacques Schrenzel
Jacques Schrenzel University of Geneva

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Related Online Degrees & Career Pathways

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