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Malcolm G. P. Page

Malcolm G. P. Page

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
8143
World Ranking
15838
National Ranking
1113

Overview

Malcolm G. P. Page is affiliated with Jacobs University in Germany and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work primarily focuses on molecular medicine, pharmacology, epidemiology, pollution, and infectious diseases.

Their research encompasses key topics such as antibiotic resistance in bacteria, antibiotics pharmacokinetics and efficacy, Pneumocystis jirovecii pneumonia detection and treatment, pharmaceutical and antibiotic environmental impacts, urinary tract infections management, antimicrobial resistance in Staphylococcus, and antibiotic use and resistance.

Malcolm G. P. Page has co-authored multiple publications with frequent collaborators including Jürgen Brem, T.M. Leissing, Pauline A. Lang, Christopher J. Schofield, and Tharindi Panduwawala.

Their scholarly output includes papers in several scientific venues such as Antimicrobial Agents and Chemotherapy, Nature Chemistry, Nature Microbiology, Biomolecules, and EcoSal Plus. Notable recent publications are:

  • Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors, 2021, Nature Chemistry
  • Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli, 2020, Biomolecules
  • Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions, 2024, Nature Microbiology
  • Structural Investigations of the Inhibition of Escherichia coli AmpC β-Lactamase by Diazabicyclooctanes, 2020, Antimicrobial Agents and Chemotherapy
  • Siderophore cephalosporins, 2025, EcoSal Plus

Best Publications

  • Membrane transport proteins: implications of sequence comparisons.

    Jeffrey K. Griffith;Michael E. Baker;Duncan A. Rouch;Malcolm G.P. Page

  • In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci.

    Paul Hebeisen;Ingrid Heinze-Krauss;Peter Angehrn;Peter Hohl

  • In Vitro Properties of BAL30072, a Novel Siderophore Sulfactam with Activity against Multiresistant Gram-Negative Bacilli

    Malcolm G. P. Page;Clothilde Dantier;Eric Desarbre

  • Structure and function of the dihydropteroate synthase from Staphylococcus aureus.

    Isabelle C Hampele;Allan D’Arcy;Glenn E Dale;Dirk Kostrewa

  • A SINGLE AMINO ACID SUBSTITUTION IN STAPHYLOCOCCUS AUREUS DIHYDROFOLATE REDUCTASE DETERMINES TRIMETHOPRIM RESISTANCE

    G. E. Dale;C. Broger;A. D'arcy;P. G. Hartman

  • Binding of Ceftobiprole and Comparators to the Penicillin-Binding Proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae

    Todd A. Davies;Malcolm G. P. Page;Wenchi Shang;Ted Andrew

  • Crystal structure of the class D beta-lactamase OXA-10.

    M. Paetzel;F. Danel;L. de Castro;S.C. Mosimann

  • Peptide Deformylase as an Antibacterial Drug Target: Target Validation and Resistance Development

    Christian M. Apfel;Hans Locher;Stefan Evers;Béla Takács

  • The Role of Iron and Siderophores in Infection, and the Development of Siderophore Antibiotics

    Malcom G P Page

  • Structural and kinetic characterization of a beta-lactamase-inhibitor protein.

    Natalie C. J. Strynadka;Susan E. Jensen;Kathy Johns;Helen Blanchard

  • Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.

    Christian Apfel;David W. Banner;Daniel Bur;Michel Dietz

  • Impact of Specific pbp5 Mutations on Expression of β-Lactam Resistance in Enterococcus faecium

    Louis B. Rice;Louis B. Rice;Samuel Bellais;Lenore L. Carias;Rebecca Hutton-Thomas

  • Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.

    Melissa D. Barnes;Melissa D. Barnes;Marisa L. Winkler;Marisa L. Winkler;Magdalena A. Taracila;Magdalena A. Taracila;Malcolm G. Page

  • Genetic Analysis and Functional Characterization of the Streptococcus pneumoniae vic Operon

    Christian Wagner;Antoine de Saizieu;Hans-Joachim Schönfeld;Markus Kamber

  • Crystallographic and Biophysical Analysis of a Bacterial Signal Peptidase in Complex with a Lipopeptide-based Inhibitor

    Mark Paetzel;Jonathon J. Goodall;Malgosia Kania;Ross E. Dalbey

  • Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins.

    Silvia Acosta-Gutiérrez;Luana Ferrara;Monisha Pathania;Muriel Masi

  • Structure-based design of beta-lactamase inhibitors. 1. Synthesis and evaluation of bridged monobactams.

    Ingrid Heinze-Krauss;Peter Angehrn;Robert L. Charnas;Klaus Gubernator

  • Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus.

    M. Hennig;A. D'Arcy;I.C. Hampele;M.G. Page

  • Antimicrobial and DNA Gyrase-Inhibitory Activities of Novel Clorobiocin Derivatives Produced by Mutasynthesis

    Ute Galm;Stefanie Heller;Stuart Shapiro;Malcolm Page

  • Design, Synthesis, and Evaluation of 2β-Alkenyl Penam Sulfone Acids as Inhibitors of β-Lactamases†

    Hans G. F. Richter;Peter Angehrn;Christian Hubschwerlen;Malgosia Kania

Frequent Co-Authors

James H. Naismith
James H. Naismith Rosalind Franklin Institute
Robert A. Bonomo
Robert A. Bonomo Case Western Reserve University
Thilo Köhler
Thilo Köhler University of Geneva
Karen Bush
Karen Bush Indiana University
Natalie C. J. Strynadka
Natalie C. J. Strynadka University of British Columbia
Andrea M. Hujer
Andrea M. Hujer United States Department of Veterans Affairs
Louis B. Rice
Louis B. Rice Brown University
Krisztina M. Papp-Wallace
Krisztina M. Papp-Wallace Case Western Reserve University
Andrea Endimiani
Andrea Endimiani University of Bern
Hanno Langen
Hanno Langen Roche (Switzerland)

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