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D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
14633
World Ranking
9670
National Ranking
4265

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Stephen W. White is affiliated with St. Jude Children's Research Hospital in the United States. Their research spans the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Organic Chemistry, Neurology, Materials Chemistry, and Genetics as subfields.

The main topics covered in their work include:

  • RNA and protein synthesis mechanisms
  • Neurological diseases and metabolism
  • Protein Degradation and Inhibitors
  • Synthesis and biological activity
  • Bacterial Genetics and Biotechnology
  • Ubiquitin and proteasome pathways
  • Multiple Myeloma Research and Treatments

Stephen W. White has contributed multiple publications in key scientific venues. The primary journals in which they have published include:

  • Journal of Medicinal Chemistry
  • UNC Libraries
  • Science Translational Medicine
  • Nucleic Acids Research
  • Journal of Biological Chemistry

Recent published papers by Stephen W. White encompass the following titles, years, and venues:

  • Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs, 2021, Angewandte Chemie International Edition
  • Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents, 2021, Journal of Medicinal Chemistry
  • Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer, 2020, Cancer Research
  • Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma, 2022, Science Translational Medicine
  • Pantothenate kinase activation relieves coenzyme A sequestration and improves mitochondrial function in mice with propionic acidemia, 2021, Science Translational Medicine

Their frequent coauthors include:

  • Mi-Kyung Yun
  • Richard Lee
  • Charles O. Rock
  • Zoran Ranković
  • Brandon Young

Stephen W. White was honored as a Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

    Stephen W. White;Jie Zheng;Yo ng-Mei Zhang;Charles O. Rock

  • Biased Signaling Pathways in β2-Adrenergic Receptor Characterized by 19F-NMR

    Jeffrey J. Liu;Reto Horst;Vsevolod Katritch;Raymond C. Stevens

  • Validation of molecular docking programs for virtual screening against dihydropteroate synthase.

    Kirk E. Hevener;Wei Zhao;Wei Zhao;David M. Ball;David M. Ball;Kerim Babaoglu;Kerim Babaoglu

  • Lipid biosynthesis as a target for antibacterial agents.

    Richard J. Heath;Stephen W. White;Stephen W. White;Charles O. Rock;Charles O. Rock

  • Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism.

    Allen C. Price;Keum-Hwa Choi;Richard J. Heath;Zhenmei Li

  • A Detailed View of a Ribosomal Active Site: The Structure of the L11–RNA Complex

    Brian T Wimberly;Rebecca Guymon;John P McCutcheon;Stephen W White

  • The 1.8 Å crystal structure and active-site architecture of β-ketoacyl-acyl carrier protein synthase III (FabH) from Escherichia coli

    Christopher Davies;Richard J Heath;Stephen W White;Stephen W White;Charles O Rock;Charles O Rock

  • Inhibiting bacterial fatty acid synthesis

    Yong-Mei Zhang;Stephen W. White;Charles O. Rock

  • Catalysis and sulfa drug resistance in dihydropteroate synthase.

    Mi Kyung Yun;Yinan Wu;Yinan Wu;Zhenmei Li;Ying Zhao

  • Inhibitors of fatty acid synthesis as antimicrobial chemotherapeutics

    R J Heath;S W White;C O Rock

  • Ribosomal protein structures: insights into the architecture, machinery and evolution of the ribosome

    V Ramakrishnan;Stephen W White

  • The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA

    V. Ramakrishnan;V. Ramakrishnan;Stephen W. White

  • Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III.

    Yong-Mei Zhang;Mohan S. Rao;Richard J. Heath;Allen C. Price

  • PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

    Ariele Viacava Follis;Jerry E Chipuk;Jerry E Chipuk;John C Fisher;John C Fisher;Mi-Kyung Yun

  • Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis.

    Allen C. Price;Yong-Mei Zhang;Charles O. Rock;Stephen W. White

  • Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

    Karin C. Nitiss;Mobeen Malik;Xiaoping He;Stephen W. White

  • Structural polymorphism in the N-terminal oligomerization domain of NPM1

    Diana M. Mitrea;Christy R. Grace;Marija Buljan;Mi-Kyung Yun

  • Cofactor-Induced Conformational Rearrangements Establish a Catalytically Competent Active Site and a Proton Relay Conduit in FabG

    Allen C Price;Yong-Mei Zhang;Charles O Rock;Charles O Rock;Stephen W White;Stephen W White

  • Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing

    Sherri Surman;Timothy D. Lockey;Karen S. Slobod;Bart Jones

  • Structural study of the calcifying collagen in turkey leg tendons.

    Carmen Berthet-Colominas;Andrew Miller;Stephen W. White

Frequent Co-Authors

Charles O. Rock
Charles O. Rock St. Jude Children's Research Hospital
Richard E. Lee
Richard E. Lee St. Jude Children's Research Hospital
Yong-Mei Zhang
Yong-Mei Zhang Medical University of South Carolina
Venki Ramakrishnan
Venki Ramakrishnan MRC Laboratory of Molecular Biology
Wei Li
Wei Li University of Tennessee Health Science Center
Keith S. Wilson
Keith S. Wilson University of York
Suzanne Jackowski
Suzanne Jackowski St. Jude Children's Research Hospital
Isao Tanaka
Isao Tanaka Hokkaido University
Jun J. Yang
Jun J. Yang St. Jude Children's Research Hospital
Kenneth N. Kreuzer
Kenneth N. Kreuzer Duke University

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