World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
11364
World Ranking
16580
National Ranking
6860

John L. Nitiss publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John L. Nitiss sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 131 publications — 17th percentile

17% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John L. Nitiss D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John L. Nitiss sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 52 D-Index — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

John L. Nitiss is affiliated with the University of Illinois at Chicago in the United States. Their research focuses on areas intersecting biochemistry, genetics, molecular biology, and medicine. In particular, their work spans molecular biology, oncology, organic chemistry, molecular medicine, and pharmacology.

The scientist's areas of study include cancer therapeutics and mechanisms, lung cancer research studies, DNA repair mechanisms, biochemical and molecular research, polyomavirus and related diseases, antibiotic resistance in bacteria, and DNA and nucleic acid chemistry.

Recent publications by John L. Nitiss showcase their contributions to understanding DNA repair and cancer biology. Notable papers include:

  • A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation (2020, Science Advances)
  • Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers (2022, Proceedings of the National Academy of Sciences)
  • Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast (2020, Proceedings of the National Academy of Sciences)
  • Topoisomerase Assays (2021, Current Protocols)
  • Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity (2022, Oncotarget)

These papers reflect a strong focus on topoisomerase enzymes and their role in DNA damage and repair processes, particularly in cancer contexts.

Frequent collaborators include Karin C. Nitiss, Yilun Sun, James M. Berger, Nilusha L. Kariyawasam, and Yves Pommier. Such collaborations have contributed to publications in prominent venues including the Proceedings of the National Academy of Sciences, Frontiers in Molecular Biosciences, bioRxiv (Cold Spring Harbor Laboratory), Science Advances, and Biophysical Journal.

John L. Nitiss has received recognition from the scientific community, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • Targeting DNA topoisomerase II in cancer chemotherapy

    John L. Nitiss

  • DNA topoisomerase II and its growing repertoire of biological functions

    John L. Nitiss

  • Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

    Yves Pommier;Yilun Sun;Shar Yin N Huang;John L. Nitiss

  • DNA topoisomerase-targeting antitumor drugs can be studied in yeast

    John Nitiss;James C. Wang

  • Investigating the biological functions of DNA topoisomerases in eukaryotic cells.

    John L. Nitiss

  • Repair of topoisomerase I-mediated DNA damage.

    Yves Pommier;Juana M. Barcelo;Juana M. Barcelo;V. Ashutosh Rao;V. Ashutosh Rao;Olivier Sordet;Olivier Sordet

  • Biologically active carbazole alkaloids from Murraya koenigii

    Russel S. Ramsewak;Muraleedharan G. Nair;Gale M. Strasburg;David L. DeWitt

  • Antitopoisomerase drug action and resistance

    John L. Nitiss;William T. Beck;William T. Beck

  • Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA.

    John L. Nitiss;James C. Wang

  • Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II.

    John L. Nitiss;Ya Xia Liu;Pelle Harbury;Mehrdad Jannatipour

  • DNA topoisomerase II as a target for cancer chemotherapy.

    Jerrylaine V. Walker;John L. Nitiss

  • Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

    Karin C. Nitiss;Mobeen Malik;Xiaoping He;Stephen W. White

  • Cytotoxicity of quinolones toward eukaryotic cells. Identification of topoisomerase II as the primary cellular target for the quinolone CP-115,953 in yeast.

    Sarah H. Elsea;Neil Osheroff;John L. Nitiss

  • Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

    Sachin Katyal;Youngsoo Lee;Karin C Nitiss;Susanna M Downing

  • Metabolites of daidzein and genistein and their biological activities

    Yu Chen Chang;Muraleedharan G. Nair;John L. Nitiss

  • Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)

    Rui Gao;Matthew J. Schellenberg;Shar Yin N. Huang;Monica Abdelmalak

  • Topoisomerase I-mediated Cytotoxicity of N-Methyl-N′-nitro-N-nitrosoguanidine: Trapping of Topoisomerase I by the O6-Methylguanine

    Philippe Pourquier;Jessica L. Waltman;Yoshimasa Urasaki;Natalia A. Loktionova

  • A Yeast Type II Topoisomerase Selected for Resistance to Quinolones MUTATION OF HISTIDINE 1012 TO TYROSINE CONFERS RESISTANCE TO NONINTERCALATIVE DRUGS BUT HYPERSENSITIVITY TO ELLIPTICINE

    Sarah H. Elsea;Yuchu Hsiung;John L. Nitiss;Neil Osheroff

  • A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: a genetic system for determining the targets of topoisomerase II inhibitors.

    Nitiss Jl;Liu Yx;Hsiung Y

  • A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines.

    Lars H. Jensen;Karin C. Nitiss;Angela Rose;Jiaowang Dong

Frequent Co-Authors

Maxwell Sehested
Maxwell Sehested Rigshospitalet
Neil Osheroff
Neil Osheroff Vanderbilt University
Yves Pommier
Yves Pommier National Institutes of Health
James C. Wang
James C. Wang Harvard University
Michael A. Resnick
Michael A. Resnick National Institutes of Health
James M. Berger
James M. Berger Johns Hopkins University
Sue Jinks-Robertson
Sue Jinks-Robertson Duke University
William T. Beck
William T. Beck University of Illinois at Chicago
Stephen W. White
Stephen W. White St. Jude Children's Research Hospital
Christophe Marchand
Christophe Marchand National Institutes of Health

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