World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
72
Citations
18954
World Ranking
1316
National Ranking
675

Overview

Peter J. McKinnon is affiliated with St. Jude Children's Research Hospital in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with substantial work also in Medicine. The scientist's subfields of study include Molecular Biology, Oncology, Cancer Research, Genetics, and Plant Science.

The scientific focus covers several critical topics, including DNA Repair Mechanisms, PARP inhibition in cancer therapy, CRISPR and Genetic Engineering, Cancer-related Molecular Pathways, Glioma Diagnosis and Treatment, interferon and immune responses, and RNA Research and Splicing.

Among the recent papers authored or co-authored by Peter J. McKinnon are:

  • Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures, 2021, EMBO Reports
  • Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair, 2021, Neuron
  • Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage-induced neurodegeneration, 2021, Science Advances
  • The dystonia gene THAP1 controls DNA double-strand break repair choice, 2021, Molecular Cell
  • A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation, 2021, eLife

Frequent co-authors collaborating with Peter J. McKinnon include H. R. Russell, Lavinia C. Dumitrache, Demis Menolfi, Brian J. Lee, and Shan Zha.

Regarding publication venues, the scientist often publishes in bioRxiv (Cold Spring Harbor Laboratory), Molecular Cell, Neuron, EMBO Reports, and Science Advances.

Best Publications

  • Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

    John R. Jeffers;Evan Parganas;Evan Parganas;Youngsoo Lee;Chunying Yang

  • Subtypes of medulloblastoma have distinct developmental origins

    Paul Gibson;Yiai Tong;Giles Robinson;Margaret C. Thompson

  • Requirement for Atm in Ionizing Radiation-Induced Cell Death in the Developing Central Nervous System

    Karl-Heinz Herzog;Miriam J. Chong;Manuela Kapsetaki;James I. Morgan

  • Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development

    Oleg V. Lagutin;Changqi C. Zhu;Daisuke Kobayashi;Jacek Topczewski

  • Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.

    Risa Kitagawa;Christopher J. Bakkenist;Peter J. McKinnon;Michael B. Kastan

  • ATM and ataxia telangiectasia.

    Peter J McKinnon

  • Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

    Jacqueline H. Barlow;Robert B. Faryabi;Elsa Callén;Nancy Wong

  • The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

    Ivan Ahel;Ulrich Rass;Sherif F. El-Khamisy;Sherif F. El-Khamisy;Sachin Katyal

  • Bat3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion

    Manu Rangachari;Chen Zhu;Kaori Sakuishi;Sheng Xiao

  • Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells.

    Elke Pogge von Strandmann;Venkateswara Rao Simhadri;Bastian von Tresckow;Stephanie Sasse

  • A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

    Matilde Murga;Samuel Bunting;Maria F Montaña;Rebeca Soria

  • DNA repair deficiency and neurological disease

    Peter J. McKinnon

  • DNA strand break repair and human genetic disease.

    Peter J. McKinnon;Keith W. Caldecott

  • DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation.

    Deniz Simsek;Erika Brunet;Erika Brunet;Sunnie Yan-Wai Wong;Sachin Katyal

  • Genome Organization Drives Chromosome Fragility

    Andres Canela;Yaakov Maman;Seolkyoung Jung;Nancy Wong

  • Clinical, Histopathologic, and Molecular Markers of Prognosis: Toward a New Disease Risk Stratification System for Medulloblastoma

    Amar Gajjar;Roberto Hernan;Mehmet Kocak;Christine Fuller

  • Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer.

    Kevin Spring;Farida Ahangari;Shaun P. Scott;Paul Waring

  • Loss of suppressor-of-fused function promotes tumorigenesis.

    Y Lee;R Kawagoe;K Sasai;Y Li

  • ATM and the Molecular Pathogenesis of Ataxia Telangiectasia

    Peter J. McKinnon

  • Maintaining genome stability in the nervous system

    Peter J McKinnon

Frequent Co-Authors

Keith W. Caldecott
Keith W. Caldecott University of Sussex
David W. Ellison
David W. Ellison St. Jude Children's Research Hospital
Suzanne J. Baker
Suzanne J. Baker St. Jude Children's Research Hospital
Martine F. Roussel
Martine F. Roussel St. Jude Children's Research Hospital
André Nussenzweig
André Nussenzweig National Institutes of Health
Steven C. Clifford
Steven C. Clifford Newcastle University
Tom Curran
Tom Curran Children's Mercy Hospital
Martin F. Lavin
Martin F. Lavin University of Queensland
Elsa Callen
Elsa Callen National Institutes of Health
Amar Gajjar
Amar Gajjar St. Jude Children's Research Hospital

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Molecular Biology can open doors to a variety of related online degrees and career paths in the health and life sciences. Many students choose to complement their laboratory expertise with advanced study in fields like mental health counseling or psychology. For those interested in counseling, pursuing a master of mental health online can provide a flexible option to develop valuable assessment and communication skills.

Another fast-growing field is forensic psychology. Curious about earnings? Find out how much does a forensic psychologist make and explore how professionals are combining science with the legal system. Those passionate about supporting young people might be drawn to a child and adolescent psychology masters degree, which focuses on psychological development and well-being in younger populations.

For greater affordability, students can consider a variety of counseling masters programs online. These programs offer flexible, accessible ways to enhance your qualifications and expand your career options after studying Molecular Biology.

Best Scientists Citing Peter J. McKinnon

Trending Scientists

Recently Published Articles