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Biology and Biochemistry

D-Index
66
Citations
30418
World Ranking
8446
National Ranking
654

Overview

Steven C. Clifford is affiliated with Newcastle University in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in Genetics, Molecular Biology, Cancer Research, Oncology, and Neurology.

The scientist's work covers a range of topics connected to cancer and neurological diseases. Main topics include:

  • Glioma Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Chromatin Remodeling and Cancer
  • Hedgehog Signaling Pathway Studies
  • Epigenetics and DNA Methylation
  • Cancer-related molecular mechanisms research
  • Neuroblastoma Research and Treatments

Steven C. Clifford has published extensively, with some of their recent papers listed below:

  • "Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity" (2020, Nature Communications)
  • "Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study" (2020, The Lancet Child & Adolescent Health)
  • "Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development" (2022, Cell Reports)
  • "Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse" (2021, Neuro-Oncology)
  • "SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma" (2021, Cancers)

The venues where Steven C. Clifford frequently publishes research include:

  • Neuro-Oncology
  • Nature Communications
  • Cancer Research
  • Cancers
  • Neuropathology and Applied Neurobiology

Collaborations form a notable part of Steven C. Clifford's work. Frequent co-authors are:

  • Ed C. Schwalbe
  • Simon Bailey
  • Debbie Hicks
  • Daniel Williamson
  • Stephen Crosier

Best Publications

  • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

    Patrick H. Maxwell;Michael S. Wiesener;Gin-Wen Chang;Steven C. Clifford

  • Molecular Subgroups of Medulloblastoma: The Current Consensus

    Michael D. Taylor;Paul A. Northcott;Andrey Korshunov;Marc Remke;Marc Remke

  • Medulloblastoma Comprises Four Distinct Molecular Variants

    Paul A. Northcott;Andrey Korshunov;Hendrik Witt;Thomas Hielscher

  • Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.

    Matthew E. Cockman;Norma Masson;David R. Mole;Panu Jaakkola

  • Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

    Marcel Kool;Andrey Korshunov;Marc Remke;Marc Remke;David T.W. Jones

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • Dissecting the genomic complexity underlying medulloblastoma

    David T. W. Jones;Natalie Jäger;Marcel Kool;Thomas Zichner

  • Subtypes of medulloblastoma have distinct developmental origins

    Paul Gibson;Yiai Tong;Giles Robinson;Margaret C. Thompson

  • Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

    Marcel Kool;Jan Koster;Jens Bunt;Nancy E. Hasselt

  • Risk stratification of childhood medulloblastoma in the molecular era: the current consensus

    Vijay Ramaswamy;Marc Remke;Eric Bouffet;Simon Bailey

  • Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

    David W. Ellison;James Dalton;Mehmet Kocak;Sarah Leigh Nicholson

  • Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

    Nataliya Zhukova;Vijay Ramaswamy;Marc Remke;Elke Pfaff

  • Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

    Edward C Schwalbe;Edward C Schwalbe;Janet C Lindsey;Sirintra Nakjang;Stephen Crosier

  • β-Catenin Status Predicts a Favorable Outcome in Childhood Medulloblastoma: The United Kingdom Children's Cancer Study Group Brain Tumour Committee

    David W. Ellison;Olabisi E. Onilude;Janet C. Lindsey;Meryl E. Lusher

  • Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.

    Steven C Clifford;Matthew E Cockman;Alan C Smallwood;David R Mole

  • Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis.

    Steven C. Clifford;Amanda H. Prowse;Nabeel A. Affara;Charles H. C. M. Buys

  • Divergent clonal selection dominates medulloblastoma at recurrence

    A. Sorana Morrissy;Livia Garzia;David J.H. Shih;Scott Zuyderduyn

  • Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables

    David W. Ellison;Mehmet Kocak;James Dalton;James Dalton;Hisham Megahed;Hisham Megahed

  • Cytogenetic Prognostication Within Medulloblastoma Subgroups

    David J.H. Shih;Paul A. Northcott;Marc Remke;Andrey Korshunov

  • Hyperfractionated Versus Conventional Radiotherapy Followed by Chemotherapy in Standard-Risk Medulloblastoma: Results From the Randomized Multicenter HIT-SIOP PNET 4 Trial

    Birgitta Lannering;Stefan Rutkowski;Francois Doz;Barry Pizer

Frequent Co-Authors

Simon Bailey
Simon Bailey Royal Victoria Infirmary
David W. Ellison
David W. Ellison St. Jude Children's Research Hospital
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Richard J. Gilbertson
Richard J. Gilbertson University of Cambridge
Michael D. Taylor
Michael D. Taylor University of Toronto
Stefan Rutkowski
Stefan Rutkowski Universität Hamburg
Torsten Pietsch
Torsten Pietsch University of Bonn
Marc Remke
Marc Remke German Cancer Research Center
François Doz
François Doz Université Paris Cité
Paul A. Northcott
Paul A. Northcott St. Jude Children's Research Hospital

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