World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
102
Citations
47577
World Ranking
491
National Ranking
275

Medicine

D-Index
109
Citations
50628
World Ranking
5719
National Ranking
3074

Research.com Recognitions

  • 2019 - Member of the National Academy of Sciences
  • 2011 - Fellow of the American Academy of Arts and Sciences

Overview

Martine F. Roussel is affiliated with St. Jude Children's Research Hospital in the United States. Their research spans numerous aspects of molecular biology and medicine, particularly within biochemistry, genetics, and oncology. They have published extensively, with a notable focus on pediatric brain tumors, protein degradation pathways, and immunotherapy strategies.

Their work covers a broad range of topics, including:

  • Glioma Diagnosis and Treatment
  • Protein Degradation and Inhibitors
  • CAR-T cell therapy research
  • Ubiquitin and proteasome pathways
  • Immunotherapy and Immune Responses
  • Multiple Myeloma Research and Treatments
  • Neuroblastoma Research and Treatments

Main fields of study for their research are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, the primary subfields of investigation include:

  • Molecular Biology
  • Genetics
  • Oncology
  • Immunology
  • Neurology

Martine F. Roussel has contributed to a wide array of publications. Some of the recent notable papers include:

  • Failure of human rhombic lip differentiation underlies medulloblastoma formation, 2022, Nature
  • Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery, 2020, Neuro-Oncology
  • Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs, 2021, Angewandte Chemie International Edition
  • Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators, 2021, Journal of Medicinal Chemistry
  • Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource, 2020, Acta Neuropathologica

Their publications appear frequently in several journals and venues, including:

  • Neuro-Oncology
  • Cancer Research
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Revue Neurologique
  • Nature Communications

Among frequent collaborators are:

  • Giles Robinson
  • Barbara Jonchère
  • Zoran Ranković
  • Brent A. Orr
  • Paul A. Northcott

Martine F. Roussel has been recognized with several honors, including being named a Member of the National Academy of Sciences in 2019 and a Fellow of the American Academy of Arts and Sciences in 2011.

Best Publications

  • Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

    J. Alan Diehl;Mangeng Cheng;Martine F. Roussel;Charles J. Sherr

  • Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19 ARF

    Takehiko Kamijo;Frederique Zindy;Martine F. Roussel;Dawn E. Quelle

  • The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

    Charles J. Sherr;Carl W. Rettenmier;Rosalba Sacca;Martine F Roussel

  • Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

    Hitoshl Matsushime;Martine F. Roussel;Martine F. Roussel;Richard A. Ashmun;Charles J. Sherr;Charles J. Sherr

  • Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

    Frederique Zindy;Christine M. Eischen;David H. Randle;Takehiko Kamijo

  • The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts.

    Mangeng Cheng;Paul Olivier;Paul Olivier;J.Alan Diehl;J.Alan Diehl;Matthew Fero;Matthew Fero

  • Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

    D. E. Quelle;R. A. Ashmun;S. A. Shurtleff;Jun-Ya Kato

  • Nucleolar Arf sequesters Mdm2 and activates p53.

    Jason D. Weber;Jason D. Weber;Laura J. Taylor;Martine F. Roussel;Charles J. Sherr

  • Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

    Hitoshi Matsushime;Mark E. Ewen;David K. Strom;Jun-Ya Kato

  • Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

    Takehiko Kamijo;Jason D. Weber;Gerard Zambetti;Frederique Zindy

  • Disruption of the ARF–Mdm2–p53 tumor suppressor pathway in Myc-induced lymphomagenesis

    Christine M. Eischen;Jason D. Weber;Martine F. Roussel;Charles J. Sherr

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • Novel INK4 Proteins, p19 and p18, Are Specific Inhibitors of the Cyclin D-Dependent Kinases CDK4 and CDK6

    H. Hirai;M. F. Roussel;Jun-Ya Kato;R. A. Ashmun

  • Subtypes of medulloblastoma have distinct developmental origins

    Paul Gibson;Yiai Tong;Giles Robinson;Margaret C. Thompson

  • Novel mutations target distinct subgroups of medulloblastoma

    Giles Robinson;Matthew Parker;Tanya A. Kranenburg;Charles Lu;Charles Lu

  • E1A signaling to p53 involves the p19(ARF) tumor suppressor.

    Elisa de Stanchina;Mila E. McCurrach;Frederique Zindy;Sheau-Yann Shieh

  • Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

    Mangeng Cheng;Veronika Sexl;Charles J. Sherr;Martine F. Roussel

  • Expression of the p16INK4A tumor suppressor versus other INK4 family members during mouse development and aging

    Frederique Zindy;Dawn E Quelle;Martine F Roussel;Charles J Sherr

  • A VARIANT EWING'S SARCOMA TRANSLOCATION (7;22) FUSES THE EWS GENE TO THE ETS GENE ETV1

    In-Sang Jeon;J. N. Davis;B. S. Braun;J. E. Sublett

  • p53-independent functions of the p19ARF tumor suppressor

    Jason D. Weber;John R. Jeffers;Jerold E. Rehg;David H. Randle

Frequent Co-Authors

Charles J. Sherr
Charles J. Sherr St. Jude Children's Research Hospital
Richard J. Gilbertson
Richard J. Gilbertson University of Cambridge
Amar Gajjar
Amar Gajjar St. Jude Children's Research Hospital
Clinton F. Stewart
Clinton F. Stewart St. Jude Children's Research Hospital
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
David Finkelstein
David Finkelstein St. Jude Children's Research Hospital
James R. Downing
James R. Downing St. Jude Children's Research Hospital
Pierre Krystkowiak
Pierre Krystkowiak University of Picardie Jules Verne
David W. Ellison
David W. Ellison St. Jude Children's Research Hospital
John L. Cleveland
John L. Cleveland Moffitt Cancer Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology can open the door to a variety of related careers in healthcare and science. Many students consider online degrees for greater flexibility and faster entry into dynamic fields. A popular route is pursuing allied health programs, such as accredited speech pathology programs, which ensure rigorous training and meet key professional standards.

If you have a background in Molecular Biology or a related field, but not directly in communication sciences, you might be interested in speech pathology bridge programs. These bridge programs are specifically designed to help non-SLP majors transition smoothly into advanced graduate studies.

For students looking to move quickly into nursing, there are accelerated nursing programs for non nurses online. These accelerated pathways help graduates pivot into high-demand healthcare roles in less time.

For those considering advanced practice, reviewing potential earnings is smart. Nurse practitioners specializing in psychiatry, for instance, can find comprehensive data on the dnp pmhnp salary to inform their career decisions. With the right online degree or transition program, Molecular Biology graduates have diverse, rewarding options in healthcare and beyond.

Best Scientists Citing Martine F. Roussel

Trending Scientists

Recently Published Articles