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Molecular Biology
Spain
2026

D-Index & Metrics

Molecular Biology

D-Index
105
Citations
83848
World Ranking
438
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Spain Leader Award
  • 2025 - Research.com Molecular Biology in Spain Leader Award
  • 2023 - Research.com Molecular Biology in Spain Leader Award

Overview

Manuel Serrano is affiliated with the Institució Catalana de Recerca i Estudis Avançats in Spain. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with notable contributions to subfields such as Molecular Biology, Physiology, Immunology, Pulmonary and Respiratory Medicine, and Aging.

The main topics addressed in Serrano's work include Telomeres, Telomerase, and Senescence; Pluripotent Stem Cells Research; Genetics, Aging, and Longevity in Model Organisms; Epigenetics and DNA Methylation; CRISPR and Genetic Engineering; RNA modifications and cancer; and Immunotherapy and Immune Responses.

Serrano has authored several recent research papers, among which are:

  • Hallmarks of aging: An expanding universe (2023, Cell)
  • Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity (2022, Cancer Discovery)
  • Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity (2020, Aging Cell)
  • Restoration of energy homeostasis by SIRT6 extends healthy lifespan (2021, Nature Communications)
  • Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype (2023, Nature Metabolism)

The frequent co-authors collaborating with Serrano include Cian J. Lynch, Camille Stephan-Otto Attolini, Neus Prats, Marta Kovatcheva, and María Abad.

Serrano's publications have appeared in several scientific venues with higher activity in:

  • bioRxiv (Cold Spring Harbor Laboratory) with 13 publications
  • Nature Communications with 7 publications
  • Aging Cell with 4 publications
  • Stem Cell Reports with 4 publications
  • International Journal of Molecular Sciences with 3 publications

Best Publications

  • The Hallmarks of Aging

    Carlos López-Otín;Maria A. Blasco;Linda Partridge;Manuel Serrano

  • Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

    Manuel Serrano;Athena W Lin;Mila E McCurrach;David Beach;David Beach

  • Cellular senescence: from physiology to pathology.

    Daniel Muñoz-Espín;Manuel Serrano

  • Cellular Senescence: Defining a Path Forward

    Vassilis Gorgoulis;Peter D. Adams;Andrea Alimonti;Dorothy C. Bennett

  • Tumour biology: Senescence in premalignant tumours

    Manuel Collado;Jesús Gil;Alejo Efeyan;Carmen Guerra

  • Cellular Senescence in Cancer and Aging

    Manuel Collado;Maria A. Blasco;Manuel Serrano

  • Role of the INK4a locus in tumor suppression and cell mortality

    Manuel Serrano;Han Woong Lee;Lynda Chin;Carlos Cordon-Cardo

  • Programmed Cell Senescence during Mammalian Embryonic Development

    Daniel Muñoz-Espín;Marta Cañamero;Antonio Maraver;Gonzalo Gómez-López

  • Senescence in tumours: evidence from mice and humans

    Manuel Collado;Manuel Serrano

  • The common biology of cancer and ageing

    Toren Finkel;Manuel Serrano;Maria A. Blasco

  • A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

    Rosa M. Marión;Katerina Strati;Han Li;Matilde Murga

  • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

    Athena W. Lin;Marta Barradas;James C. Stone;Linda van Aelst

  • Sirt1 protects against high-fat diet-induced metabolic damage

    Paul T. Pfluger;Daniel Herranz;Susana Velasco-Miguel;Manuel Serrano

  • The Ink4/Arf locus is a barrier for iPS cell reprogramming

    Han Li;Manuel Collado;Aranzazu Villasante;Katerina Strati

  • Mutations and altered expression of p16INK4 in human cancer

    A Okamoto;D J Demetrick;E A Spillare;K Hagiwara

  • p19ARF links the tumour suppressor p53 to Ras

    Ignacio Palmero;Cristina Pantoja;Manuel Serrano

  • Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

    Daniel Herranz;Maribel Muñoz-Martin;Marta Cañamero;Francisca Mulero

  • Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

    Carmen Guerra;Nieves Mijimolle;Alma Dhawahir;Pierre Dubus

  • "Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally.

    Isabel García-Cao;Marta García-Cao;Juan Martín-Caballero;Luis M. Criado

  • Putting the stress on senescence

    Manuel Serrano;Marı́a A Blasco

Frequent Co-Authors

Maria A. Blasco
Maria A. Blasco Spanish National Cancer Research Centre
David Beach
David Beach Cold Spring Harbor Laboratory
Juana M. Flores
Juana M. Flores Complutense University of Madrid
Gonzalo Gómez-López
Gonzalo Gómez-López Universidade de Vigo
Margarita Salas
Margarita Salas Spanish National Research Council
Maria T. Diaz-Meco
Maria T. Diaz-Meco Cornell University
Jorge Moscat
Jorge Moscat Cornell University
Peter Klatt
Peter Klatt Spanish National Research Council
Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Mario F. Fraga
Mario F. Fraga University of Oviedo

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