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Maria T. Diaz-Meco

Maria T. Diaz-Meco

D-Index & Metrics

Molecular Biology

D-Index
91
Citations
44281
World Ranking
713
National Ranking
387

Overview

Maria T. Diaz-Meco is affiliated with the Discovery Institute in the United States. Their research activity is primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions notably in Molecular Biology and Oncology.

Their work covers specialized subfields including Epidemiology, Cancer Research, and Immunology. Major topics addressed in their research include Cancer Cells and Metastasis, Autophagy in Disease and Therapy, and Epigenetics and DNA Methylation. Additional areas of focus encompass Genetic factors in colorectal cancer, Cancer Immunotherapy and Biomarkers, Genomics, phytochemicals, and oxidative stress, as well as Endoplasmic Reticulum Stress and Disease.

Recent publications by Maria T. Diaz-Meco demonstrate a focus on cellular mechanisms in cancer and metabolism across high-impact journals:

  • Fructose stimulated de novo lipogenesis is promoted by inflammation (2020), Nature Metabolism
  • Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis (2021), Cancer Cell
  • PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression (2020), Cancer Cell
  • Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population (2020), Developmental Cell
  • NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly (2020), Journal of Hepatology

Several frequent collaborators have been identified alongside Diaz-Meco, indicating a network of ongoing research partnerships:

  • Jorge Moscat
  • Ángeles Durán
  • Juan F. Linares
  • Tania Cid-Diaz
  • Anxo Martínez-Ordóñez

The explorer of biomedical questions has published extensively in notable venues, including:

  • Nature Communications
  • STAR Protocols
  • Cancer Cell
  • Molecular Cell
  • Cancer Research

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

    Zhenyu Zhong;Atsushi Umemura;Atsushi Umemura;Elsa Sanchez-Lopez;Shuang Liang

  • p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

    Jorge Moscat;Maria T. Diaz-Meco

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis

    Angeles Duran;Juan F. Linares;Anita S. Galvez;Kathryn Wikenheiser

  • Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase.

    J Lozano;E Berra;M M Municio;M T Diaz-Meco

  • p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

    Angeles Duran;Ramars Amanchy;Juan F. Linares;Juan F. Linares;Jayashree Joshi

  • The atypical PKC‐interacting protein p62 channels NF‐κB activation by the IL‐1–TRAF6 pathway

    Laura Sanz;María T. Diaz‐Meco;Hiroyasu Nakano;Jorge Moscat

  • Targeted Disruption of the ζPKC Gene Results in the Impairment of the NF-κB Pathway

    Michael Leitges;Laura Sanz;Pilar Martin;Angeles Duran

  • The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.

    Laura Sanz;Pilar Sanchez;Maria‐José Lallena;María T. Diaz‐Meco

  • The Product of par-4, a Gene Induced during Apoptosis, Interacts Selectively with the Atypical Isoforms of Protein Kinase C

    María T Díaz-Meco;María M Municio;Sonia Frutos;Pilar Sanchez

  • Activation of IκB Kinase β by Protein Kinase C Isoforms

    Maria-José Lallena;María T. Diaz-Meco;Gary Bren;Carlos V. Payá

  • Protein kinase C ζ isoform is critical for mitogenic signal transduction

    Edurne Berra;Maria T. Diaz-Meco;Isabel Dominguez;Maria M. Municio

  • Essential role of RelA Ser311 phosphorylation by ζPKC in NF-κB transcriptional activation

    Angeles Duran;María T. Diaz‐Meco;Jorge Moscat

  • The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation.

    W van der Houven van Oordt;M T Diaz-Meco;J Lozano;A R Krainer

  • p62 in Cancer: Signaling Adaptor Beyond Autophagy

    Jorge Moscat;Michael Karin;Maria T. Diaz-Meco

  • p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

    Atsushi Umemura;Feng He;Koji Taniguchi;Hayato Nakagawa

  • Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase.

    H Cai;U Smola;V Wixler;I Eisenmann-Tappe

  • Signal integration and diversification through the p62 scaffold protein.

    Jorge Moscat;María T. Diaz-Meco;Marie W. Wooten

Frequent Co-Authors

Jorge Moscat
Jorge Moscat Cornell University
Michael Leitges
Michael Leitges University of Oslo
Terje Johansen
Terje Johansen University of Tromsø - The Arctic University of Norway
Manuel Serrano
Manuel Serrano Institució Catalana de Recerca i Estudis Avançats
Jose A. Cancelas
Jose A. Cancelas Cincinnati Children's Hospital Medical Center
Michael Karin
Michael Karin University of California, San Diego
Marie W. Wooten
Marie W. Wooten Auburn University
Libia Sanz
Libia Sanz Spanish National Research Council
Evelina Gatti
Evelina Gatti Aix-Marseille University
Christian M. Metallo
Christian M. Metallo University of California, San Diego

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