World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
11147
World Ranking
9903
National Ranking
4335

Overview

Jose A. Cancelas is affiliated with Cincinnati Children's Hospital Medical Center in the United States, with a research focus primarily in the field of Medicine. Their work spans several subfields, including Hematology, Genetics, Molecular Biology, Immunology, and Oncology.

The scientist's research addresses topics such as blood transfusion and management, hematopoietic stem cell transplantation, cytomegalovirus and herpesvirus research, erythrocyte function and pathophysiology, CAR-T cell therapy research, blood donation and transfusion practices, and mesenchymal stem cell research.

Key recent publications include the following papers:

  • Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma, 2020, Blood
  • Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging, 2021, Science Advances
  • Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients, 2020, PubMed
  • Hypoxic storage of red blood cells improves metabolism and post-transfusion recovery, 2020, Transfusion
  • Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted, 2021, Blood Advances

Jose A. Cancelas collaborates frequently with several researchers. Notable coauthors include Carolyn Lutzko, Stella M. Davies, Ashley M. Wellendorf, Jeremy D. Rubinstein, and Yi Zheng.

The scientist's body of work is published predominantly in venues such as Transfusion, Blood, bioRxiv (Cold Spring Harbor Laboratory), Blood Advances, and Transplantation and Cellular Therapy.

Best Publications

  • Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases.

    Yi Gu;Marie-Dominique Filippi;Jose A. Cancelas;Jose A. Cancelas;Jamie E. Siefring

  • Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization

    Jose A Cancelas;Andrew W Lee;Rethinasamy Prabhakar;Keith F Stringer

  • Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia

    Junping Wei;Mark Wunderlich;Catherine Fox;Sara Alvarez

  • Stem Cell Collection and Gene Transfer in Fanconi Anemia

    Patrick F Kelly;Susan Radtke;Christof von Kalle;Brenden Balcik

  • Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow.

    Linda Yang;Lei Wang;Hartmut Geiger;Jose A. Cancelas

  • Plexiform and Dermal Neurofibromas and Pigmentation Are Caused by Nf1 Loss in Desert Hedgehog-Expressing Cells

    Jianqiang Wu;Jon P. Williams;Tilat A. Rizvi;Jennifer J. Kordich

  • Rho GTPases in hematopoiesis and hemopathies

    James C. Mulloy;Jose A. Cancelas;Marie-Dominique Filippi;Theodosia A. Kalfa

  • Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.

    Novella Guidi;Mehmet Sacma;Ludger Ständker;Karin Soller

  • Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells

    Eri Taniguchi Ishikawa;Daniel Gonzalez-Nieto;Daniel Gonzalez-Nieto;Gabriel Ghiaur;Susan K. Dunn

  • Neuroblastoma Cell Lines Contain Pluripotent Tumor Initiating Cells That Are Susceptible to a Targeted Oncolytic Virus

    Yonatan Y. Mahller;Jon P. Williams;William H. Baird;Bryan Mitton;Bryan Mitton

  • Highly Efficient Transduction of the Green Fluorescent Protein Gene in Human Umbilical Cord Blood Stem Cells Capable of Cobblestone Formation in Long-Term Cultures and Multilineage Engraftment of Immunodeficient Mice

    Paula B. van Hennik;Monique M.A. Verstegen;Marti F.A. Bierhuizen;Ana Limón

  • Rac Guanosine Triphosphatases Represent Integrating Molecular Therapeutic Targets for BCR-ABL-Induced Myeloproliferative Disease

    Emily K. Thomas;Jose A. Cancelas;Jose A. Cancelas;Hee Don Chae;Adrienne D. Cox

  • Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development

    Fukun Guo;Jose A. Cancelas;Jose A. Cancelas;David Hildeman;David A. Williams

  • Signaling and cytoskeletal requirements in erythroblast enucleation.

    Diamantis G. Konstantinidis;Suvarnamala Pushkaran;James F. Johnson;Jose A. Cancelas

  • Connexin-43 gap junctions are involved in multiconnexin-expressing stromal support of hemopoietic progenitors and stem cells

    Jose A. Cancelas;Wendy L. M. Koevoet;Alexandra E. de Koning;Angelique E. M. Mayen

  • Structure-function based design of small molecule inhibitors targeting Rho family GTPases.

    Nicolas Nassar;Jose Cancelas;Jie Zheng;David A. Williams

  • Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition

    Carlos E. Prada;Edwin Jousma;Tilat A. Rizvi;Jianqiang Wu

  • The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization.

    Jose A. Cancelas;Michael Jansen;David A. Williams

  • Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

    Nathan Salomonis;Phillip J. Dexheimer;Larsson Omberg;Robin Schroll

  • Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity

    Hartmut Geiger;Snehalata A Pawar;Edward J Kerschen;Kalpana J Nattamai

Frequent Co-Authors

David A. Williams
David A. Williams Boston Children's Hospital
Yi Zheng
Yi Zheng Cincinnati Children's Hospital Medical Center
Hartmut Geiger
Hartmut Geiger University of Ulm
Nancy Ratner
Nancy Ratner Cincinnati Children's Hospital Medical Center
H. Leighton Grimes
H. Leighton Grimes Cincinnati Children's Hospital Medical Center
Marc E. Rothenberg
Marc E. Rothenberg Cincinnati Children's Hospital Medical Center
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center
Jorge Moscat
Jorge Moscat Cornell University
Maria T. Diaz-Meco
Maria T. Diaz-Meco Cornell University
Stella M. Davies
Stella M. Davies Cincinnati Children's Hospital Medical Center

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