World's Best Scientists 2026 revealed!
Lorenz Poellinger

Lorenz Poellinger

D-Index & Metrics

Molecular Biology

D-Index
92
Citations
32600
World Ranking
699
National Ranking
15

Overview

Lorenz Poellinger is affiliated with the Karolinska Institute in Sweden and specializes in research within the broad field of Biochemistry, Genetics, and Molecular Biology. Their body of work encompasses 12 publications predominantly focused on the subfields of Molecular Biology, Cancer Research, and Physiology.

The main topics addressed in Poellinger's research include Epigenetics and DNA Methylation, Cancer-related gene regulation, and Genomics and Chromatin Dynamics. Additional areas of investigation cover Cancer, Hypoxia, and Metabolism, RNA modifications and cancer, Cancer-related molecular mechanisms research, and Signaling Pathways in Disease.

The scientist has co-authored publications frequently with researchers such as Hisao Masai, Wendi Sun, Hiroyuki Kato, Shojiro Kitajima, and Takashi Okamoto. Their collaborative efforts span multiple studies in various scientific journals.

Poellinger has contributed articles to these prominent scientific venues:

  • Oncogene
  • Journal of Biological Chemistry
  • Epigenetics
  • Scientific Reports

Selected recent papers authored or co-authored by Lorenz Poellinger include:

  • "Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization," 2020, Oncogene
  • "Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism," 2022, Journal of Biological Chemistry
  • "Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types," 2023, Epigenetics
  • "A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition," 2021, Scientific Reports

Best Publications

  • Hypoxia Requires Notch Signaling to Maintain the Undifferentiated Cell State

    Maria V. Gustafsson;Xiaowei Zheng;Teresa Pereira;Katarina Gradin

  • Mechanism of regulation of the hypoxia‐inducible factor‐1α by the von Hippel‐Lindau tumor suppressor protein

    Keiji Tanimoto;Yuichi Makino;Teresa Pereira;Lorenz Poellinger

  • Regulation of the Hypoxia-inducible Transcription Factor 1α by the Ubiquitin-Proteasome Pathway

    Pekka J. Kallio;William J. Wilson;Sallyann O'Brien;Yuichi Makino

  • Notch signaling mediates hypoxia-induced tumor cell migration and invasion

    Cecilia Sahlgren;Maria V. Gustafsson;Shaobo Jin;Lorenz Poellinger

  • Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

    Yuichi Makino;Renhai Cao;Kristian Svensson;Göran Bertilsson

  • Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha.

    Pekka J. Kallio;Kensaku Okamoto;Kensaku Okamoto;Sallyann O'Brien;Pilar Carrero

  • Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.

    Linda Holmquist-Mengelbier;Erik Fredlund;Tobias Löfstedt;Rosa Noguera

  • Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

    Masatsugu Ema;Kiichi Hirota;Junsei Mimura;Hisaku Abe

  • Stabilization of HIF-1α is critical to improve wound healing in diabetic mice

    Ileana Ruxandra Botusan;Vivekananda Gupta Sunkari;Octavian Savu;Anca Irinel Catrina

  • Inhibitory PAS Domain Protein (IPAS) Is a Hypoxia-inducible Splicing Variant of the Hypoxia-inducible Factor-3α Locus

    Yuichi Makino;Arvydas Kanopka;William J. Wilson;Hirotoshi Tanaka

  • Redox-Regulated Recruitment of the Transcriptional Coactivators CREB-Binding Protein and SRC-1 to Hypoxia-Inducible Factor 1α

    Pilar Carrero;Kensaku Okamoto;Kensaku Okamoto;Pascal Coumailleau;Sallyann O'Brien

  • Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.

    K Gradin;J McGuire;R H Wenger;I Kvietikova

  • Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype

    Annika Jögi;Ingrid Øra;Helén Nilsson;Åsa Lindeheim

  • Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms.

    Yu Dong;Lorenz Poellinger;Jan-Åke Gustafsson;Sam Okret

  • Evidence That the Co-chaperone p23 Regulates Ligand Responsiveness of the Dioxin (Aryl Hydrocarbon) Receptor

    Arunas Kazlauskas;Lorenz Poellinger;Ingemar Pongratz

  • Generating specificity and diversity in the transcriptional response to hypoxia.

    Urban Lendahl;Kian Leong Lee;Henry Yang;Lorenz Poellinger;Lorenz Poellinger

  • Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

    Kyle M. Loh;Kyle M. Loh;Lay Teng Ang;Jingyao Zhang;Vibhor Kumar

  • Physiological activation of hypoxia inducible factor-1 in human skeletal muscle

    Helene Ameln;Thomas Gustafsson;Carl Johan Sundberg;Kensaku Okamoto;Kensaku Okamoto

  • Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

    Xiaofeng Zheng;Sarah Linke;José M. Dias;Xiaowei Zheng

  • Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor.

    Marc Denis;Scott Cuthill;Ann Charlotte Wikström;Lorenz Poellinger

Frequent Co-Authors

Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Murray L. Whitelaw
Murray L. Whitelaw University of Adelaide
Hirotoshi Tanaka
Hirotoshi Tanaka Keio University
Sam Okret
Sam Okret Karolinska Institute
Sven Pettersson
Sven Pettersson Karolinska Institute
Jan Carlstedt-Duke
Jan Carlstedt-Duke Nanyang Technological University
Rune Toftgård
Rune Toftgård Karolinska Institute
Randall S. Johnson
Randall S. Johnson University of Cambridge
Jozef Dulak
Jozef Dulak Jagiellonian University
Seppo Ylä-Herttuala
Seppo Ylä-Herttuala University of Eastern Finland

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology can open doors to many interdisciplinary careers. For students considering a shift in direction, related online degrees offer flexibility and diverse opportunities. If you’re interested in healthcare, a masters in human services online prepares graduates for supportive and administrative roles, often found in clinical and community settings.

Molecular Biology knowledge provides a strong foundation for specialized paths like speech pathology. Teachers or professionals interested in clinical communication roles may find guidance in transitioning from education to healthcare at teacher to speech language pathologist.

For those seeking a broader scientific or analytical focus, programs such as the online degree mathematics are ideal. Analytical skills gained here are highly valued in research and technology sectors.

Alternatively, blending biology with design is possible in architecture. Learners can explore STEM-related design principles through some of the best online architecture degree programs.

Whether you continue in science or pivot to a new field, these online options expand your career horizons while fostering valuable, transferable skills.

Best Scientists Citing Lorenz Poellinger

Trending Scientists

Recently Published Articles