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Lorenz Poellinger

Lorenz Poellinger

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
33367
World Ranking
1901
National Ranking
31

Overview

Lorenz Poellinger was affiliated with the Karolinska Institute in Sweden. Their research primarily focused on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology as a subfield. The scientist contributed to several topics within these fields, including epigenetics and DNA methylation, cancer-related gene regulation, genomics and chromatin dynamics, cancer, hypoxia, and metabolism, RNA modifications and cancer, cancer-related molecular mechanisms research, and signaling pathways in disease.

Poellinger's recent research output included the following publications:

  • Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization, 2020, Oncogene
  • Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism, 2022, Journal of Biological Chemistry
  • Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types, 2023, Epigenetics
  • A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition, 2021, Scientific Reports

Frequent co-authors appearing in Poellinger's collaborative work included Hisao Masai, Wendi Sun, Hiroyuki Kato, Shojiro Kitajima, and Takashi Okamoto.

Publications were regularly featured in venues such as Oncogene, Journal of Biological Chemistry, Epigenetics, and Scientific Reports.

Best Publications

  • Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife

    M. van den Berg;L. Birnbaum;A.T.C. Bosveld;B. Brunstrom

  • Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

    Yuichi Makino;Renhai Cao;Kristian Svensson;Göran Bertilsson

  • Activation of hypoxia-inducible factor 1α: Posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

    Pekka J. Kallio;Ingemar Pongratz;Katarina Gradin;Jacqueline McGuire

  • Stabilization of HIF-1α is critical to improve wound healing in diabetic mice

    Ileana Ruxandra Botusan;Vivekananda Gupta Sunkari;Octavian Savu;Anca Irinel Catrina

  • Inhibitory PAS Domain Protein (IPAS) Is a Hypoxia-inducible Splicing Variant of the Hypoxia-inducible Factor-3α Locus

    Yuichi Makino;Arvydas Kanopka;William J. Wilson;Hirotoshi Tanaka

  • Redox-Regulated Recruitment of the Transcriptional Coactivators CREB-Binding Protein and SRC-1 to Hypoxia-Inducible Factor 1α

    Pilar Carrero;Kensaku Okamoto;Kensaku Okamoto;Pascal Coumailleau;Sallyann O'Brien

  • Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.

    K Gradin;J McGuire;R H Wenger;I Kvietikova

  • Biochemistry molecular biology, and physiology of the glucocorticoid receptor

    Jan-Ake Gustafsson;J. Carlstedt-Duke;L. Poellinger;S. Okret

  • Hyperglycemia Regulates Hypoxia-Inducible Factor-1α Protein Stability and Function

    Sergiu-Bogdan Catrina;Kensaku Okamoto;Teresa Pereira;Kerstin Brismar

  • Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms.

    Yu Dong;Lorenz Poellinger;Jan-Åke Gustafsson;Sam Okret

  • S -2-hydroxyglutarate regulates CD8 + T-lymphocyte fate

    Petros A. Tyrakis;Asis Palazon;David Macias;Kian. L. Lee

  • Generating specificity and diversity in the transcriptional response to hypoxia.

    Urban Lendahl;Kian Leong Lee;Henry Yang;Lorenz Poellinger;Lorenz Poellinger

  • Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

    Kyle M. Loh;Kyle M. Loh;Lay Teng Ang;Jingyao Zhang;Vibhor Kumar

  • A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

    Patrik Andersson;Jacqueline McGuire;Carlos Rubio;Katarina Gradin

  • Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone.

    Sam Okret;Lorenz Poellinger;Yu Dong;Jan-Ake Gustafsson

  • Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

    Xiaofeng Zheng;Sarah Linke;José M. Dias;Xiaowei Zheng

  • Hypoxia-inducible factor-1α polymorphisms associated with enhanced transactivation capacity, implying clinical significance

    Keiji Tanimoto;Koji Yoshiga;Hidetaka Eguchi;Mika Kaneyasu

  • Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands.

    Kaname Kawajiri;Yasuhito Kobayashi;Fumiaki Ohtake;Togo Ikuta

  • A Constitutively Active Dioxin/Aryl Hydrocarbon Receptor Promotes Hepatocarcinogenesis in Mice

    Oliver Moennikes;Sandra Loeppen;Albrecht Buchmann;Patrik Andersson

  • Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor.

    Murray Whitelaw;Ingemar Pongratz;Anna Wilhelmsson;Jan-Ake Gustafsson

Frequent Co-Authors

Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Henry Yang
Henry Yang National University of Singapore
Murray L. Whitelaw
Murray L. Whitelaw University of Adelaide
Bing Lim
Bing Lim Thymmune Therapeutics
Urban Lendahl
Urban Lendahl Karolinska Institute
Randall S. Johnson
Randall S. Johnson University of Cambridge
Sven Pettersson
Sven Pettersson Karolinska Institute
Kerstin Brismar
Kerstin Brismar Karolinska Institute
Takashi Okamoto
Takashi Okamoto Nagoya City University
H. Phillip Koeffler
H. Phillip Koeffler Cedars-Sinai Medical Center

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