D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 11,635 72 World Ranking 13840 National Ranking 401

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Transcription factor

His main research concerns Transcription factor, Biochemistry, Aryl hydrocarbon receptor nuclear translocator, Transactivation and Hypoxia-inducible factors. His biological study spans a wide range of topics, including Signal transduction and Cell biology. His research on Biochemistry focuses in particular on Regulation of gene expression.

His work carried out in the field of Aryl hydrocarbon receptor nuclear translocator brings together such families of science as Transcription factor complex and Receptor. Murray L. Whitelaw focuses mostly in the field of Receptor, narrowing it down to matters related to Hsp90 and, in some cases, Immunoprecipitation. His Transactivation research integrates issues from Hypoxia-Inducible Factor-Proline Dioxygenases and Oxygen homeostasis.

His most cited work include:

  • Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. (1281 citations)
  • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor (1227 citations)
  • The mammalian basic helix-loop-helix/PAS family of transcriptional regulators. (436 citations)

What are the main themes of his work throughout his whole career to date?

Transcription factor, Aryl hydrocarbon receptor nuclear translocator, Biochemistry, Cell biology and Receptor are his primary areas of study. His studies in Transcription factor integrate themes in fields like Molecular biology and Response element. He interconnects Hsp90, PAS domain, Signal transduction and DNA in the investigation of issues within Aryl hydrocarbon receptor nuclear translocator.

His is involved in several facets of Biochemistry study, as is seen by his studies on 5-HT5A receptor, Asparagine, Nuclear receptor, Glucocorticoid receptor and Mutant. His research integrates issues of Regulation of gene expression, Dioxin Receptor, Transcription and Gene knockdown in his study of Cell biology. His Basic helix-loop-helix study combines topics in areas such as Sequence motif and Repressor.

He most often published in these fields:

  • Transcription factor (60.00%)
  • Aryl hydrocarbon receptor nuclear translocator (52.94%)
  • Biochemistry (47.06%)

What were the highlights of his more recent work (between 2012-2021)?

  • Transcription factor (60.00%)
  • Aryl hydrocarbon receptor nuclear translocator (52.94%)
  • Genetics (17.65%)

In recent papers he was focusing on the following fields of study:

Murray L. Whitelaw mostly deals with Transcription factor, Aryl hydrocarbon receptor nuclear translocator, Genetics, SIM1 and Loss function. His biological study focuses on Basic helix-loop-helix. The Basic helix-loop-helix study combines topics in areas such as H3K4me3, Neuron differentiation, Repressor and DNA methylation.

His Aryl hydrocarbon receptor nuclear translocator study combines topics from a wide range of disciplines, such as Hypoxia-inducible factors, Cytokine and FOXP3. His research in SIM1 intersects with topics in Endocrinology, Obesity, Internal medicine, Haploinsufficiency and SIM2. Murray L. Whitelaw has researched Bioinformatics in several fields, including Oxygen homeostasis, Physiology and HIF1A.

Between 2012 and 2021, his most popular works were:

  • bHLH–PAS proteins in cancer (126 citations)
  • The emerging roles of AhR in physiology and immunity. (118 citations)
  • Rare variants in single-minded 1 (SIM1) are associated with severe obesity. (102 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Transcription factor

The scientist’s investigation covers issues in Aryl hydrocarbon receptor nuclear translocator, SIM1, Aryl hydrocarbon receptor, Transcription factor and Loss function. Murray L. Whitelaw has included themes like Immunology, Immune system, Cytokine and Cytotoxic T cell, Antigen-presenting cell in his Aryl hydrocarbon receptor nuclear translocator study. His SIM1 research also works with subjects such as

  • Internal medicine that connect with fields like Genetics,
  • Haploinsufficiency, which have a strong connection to Penetrance.

His study in Aryl hydrocarbon receptor is interdisciplinary in nature, drawing from both Regulator, FOXP3, Computational biology and Function. His Transcription factor study integrates concerns from other disciplines, such as Cell signaling, Circadian clock and Cell biology. His Loss function research is multidisciplinary, incorporating perspectives in Young adult, Chromosome, Obesity and Case-control study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch.

David Lando;Daniel J. Peet;Dean A. Whelan;Jeffrey J. Gorman.
Science (2002)

1843 Citations

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

David Lando;Daniel J. Peet;Jeffrey J. Gorman;Dean A. Whelan.
Genes & Development (2002)

1703 Citations

The mammalian basic helix-loop-helix/PAS family of transcriptional regulators.

Robyn J Kewley;Murray L Whitelaw;Anne Chapman-Smith.
The International Journal of Biochemistry & Cell Biology (2004)

670 Citations

A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

Patrik Andersson;Jacqueline McGuire;Carlos Rubio;Katarina Gradin.
Proceedings of the National Academy of Sciences of the United States of America (2002)

332 Citations

The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses.

C. P. Bracken;M. L. Whitelaw;D. J. Peet.
Cellular and Molecular Life Sciences (2003)

321 Citations

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

Xiaofeng Zheng;Sarah Linke;José M. Dias;Xiaowei Zheng.
Proceedings of the National Academy of Sciences of the United States of America (2008)

265 Citations

Protein-protein interaction via PAS domains: role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complex.

M.C. Lindebro;L. Poellinger;M.L. Whitelaw.
The EMBO Journal (1995)

256 Citations

Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor.

Murray Whitelaw;Ingemar Pongratz;Anna Wilhelmsson;Jan-Ake Gustafsson.
Molecular and Cellular Biology (1993)

247 Citations

Cell-specific regulation of hypoxia-inducible factor (HIF)-1α and HIF-2α stabilization and transactivation in a graded oxygen environment

Cameron P. Bracken;Anthony O. Fedele;Sarah Linke;Wiltiana Balrak.
Journal of Biological Chemistry (2006)

243 Citations

Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation.

David Lando;Jeffrey J. Gorman;Murray L. Whitelaw;Daniel J. Peet.
FEBS Journal (2003)

235 Citations

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