William B. Pratt

Overview

Best Publications

• Steroid receptor interactions with heat shock protein and immunophilin chaperones.

  William B. Pratt;David O. Toft

  2573
  Citations

• Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery.

  William B. Pratt;David O. Toft

  2113
  Citations

• HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

  Jeffrey J. Kovacs;Patrick J.M. Murphy;Stéphanie Gaillard;Xuan Zhao

  1298
  Citations

• The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor

  William B. Pratt

  893
  Citations

• The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors

  William B. Pratt

  645
  Citations

• Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

  E R Sanchez;D O Toft;M J Schlesinger;W B Pratt

  592
  Citations

• The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase.

  William B. Pratt

  511
  Citations

• Evidence that the 90-kDa heat shock protein is necessary for the steroid binding conformation of the L cell glucocorticoid receptor.

  E H Bresnick;F C Dalman;E R Sanchez;W B Pratt

  508
  Citations

• Molybdate inhibition of glucocorticoid receptor inactivation and transformation.

  K L Leach;M K Dahmer;N D Hammond;J J Sando

  480
  Citations

• Proof that the endogenous, heat-stable glucocorticoid receptor-activating factor is thioredoxin.

  J F Grippo;A Holmgren;W B Pratt

  442
  Citations

• Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

  L. F. Stancato;Yu-Hua Chow;K. A. Hutchison;G. H. Perdew

  391
  Citations

• Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.

  Kurt D. Dittmar;Damon R. Demady;Louis F. Stancato;Priti Krishna

  383
  Citations

• Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement.

  William B Pratt;Mario D Galigniana;Jennifer M Harrell;Donald B DeFranco

  372
  Citations

• A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.

  W B Pratt;D J Jolly;D V Pratt;S M Hollenberg

  368
  Citations

• Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus *

  Mario D. Galigniana;Christine Radanyi;Jack Michel Renoir;Paul R. Housley

  336
  Citations

• Role of molecular chaperones in steroid receptor action.

  William B Pratt;Mario D Galigniana;Yoshihiro Morishima;Patrick J M Murphy

  330
  Citations

• Protein Phosphatase 5 Is a Major Component of Glucocorticoid Receptor·hsp90 Complexes with Properties of an FK506-binding Immunophilin

  Adam M. Silverstein;Mario D. Galigniana;Mei-Shya Chen;Janet K. Owens-Grillo

  329
  Citations

• Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex.

  Yongle Guo;Toumy Guettouche;Mary Fenna;Frank Boellmann

  312
  Citations

• The Tetratricopeptide Repeat Domain of Protein Phosphatase 5 Mediates Binding to Glucocorticoid Receptor Heterocomplexes and Acts as a Dominant Negative Mutant

  Mei Shya Chen;Adam M. Silverstein;William B. Pratt;Michael Chinkers

  307
  Citations

• Short Article HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

  Jeffrey J. Kovacs;Stéphanie Gaillard;Xuan Zhao;June-Tai Wu

  25
  Citations