D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 78 Citations 36,158 265 World Ranking 2780 National Ranking 1470

Research.com Recognitions

Awards & Achievements

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Jason E. Gestwicki focuses on Biochemistry, Cell biology, Chaperone, Receptor and Biophysics. His studies deal with areas such as Heat shock protein, Cell, Ubiquitin, Anatomy and In vivo as well as Cell biology. His Chaperone research includes themes of Neurodegeneration, Hsp70, Protein structure, Proteostasis and Allosteric regulation.

The Receptor study combines topics in areas such as Signal transduction, Ligand, Function and Effector. His work carried out in the field of Function brings together such families of science as Autophagy database, Stereochemistry, Receptor clustering and Neoplasms therapy. The study incorporates disciplines such as Extracellular, Coupling and Intracellular in addition to Stereochemistry.

His most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
  • Potential therapeutic applications of autophagy. (842 citations)

What are the main themes of his work throughout his whole career to date?

Jason E. Gestwicki mainly focuses on Cell biology, Biochemistry, Chaperone, Hsp70 and Allosteric regulation. He has included themes like Heat shock protein, Neurodegeneration, Tauopathy, Alzheimer's disease and Programmed cell death in his Cell biology study. His work in Biochemistry addresses subjects such as Biophysics, which are connected to disciplines such as Receptor.

The Receptor study which covers Function that intersects with Intracellular. Jason E. Gestwicki has researched Chaperone in several fields, including Cancer research, Protein domain, Protein folding, Hsp90 and Proteostasis. His work focuses on many connections between Small molecule and other disciplines, such as Computational biology, that overlap with his field of interest in Drug discovery.

He most often published in these fields:

  • Cell biology (34.37%)
  • Biochemistry (34.03%)
  • Chaperone (23.96%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (34.37%)
  • Hsp70 (18.40%)
  • Chaperone (23.96%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, Hsp70, Chaperone, Programmed cell death and Neurodegeneration. His Cell biology study combines topics in areas such as CRISPR interference and Tauopathy. His Hsp70 study focuses on Heat shock protein and Biochemistry.

His Heat shock protein research includes themes of Protein domain, Membrane, Computational biology and Protein–protein interaction. His research in Computational biology focuses on subjects like Binding site, which are connected to Drug discovery. His studies in Chaperone integrate themes in fields like Combinatorial chemistry, Thermal stability, A protein and Effector.

Between 2018 and 2021, his most popular works were:

  • Function, evolution, and structure of J-domain proteins (35 citations)
  • Inhibitors and chemical probes for molecular chaperone networks. (34 citations)
  • Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis (33 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

Jason E. Gestwicki mainly focuses on Cell biology, Chaperone, Heat shock protein, Protein folding and Protein aggregation. His Cell biology research is multidisciplinary, relying on both Hsp70, Ubiquitin ligase, Small molecule and Tauopathy. His study looks at the relationship between Hsp70 and topics such as HSPA9, which overlap with Programmed cell death.

His Chaperone research is multidisciplinary, incorporating perspectives in Legionella pneumophila and Computational biology. As part of the same scientific family, Jason E. Gestwicki usually focuses on Computational biology, concentrating on Drug discovery and intersecting with Proteostasis. His biological study spans a wide range of topics, including Hsp90 and Multiprotein complex.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)

8302 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

7788 Citations

Potential therapeutic applications of autophagy.

David C. Rubinsztein;Jason E. Gestwicki;Leon O. Murphy;Daniel J. Klionsky.
Nature Reviews Drug Discovery (2007)

1205 Citations

Synthetic Multivalent Ligands as Probes of Signal Transduction

Laura L. Kiessling;Jason E. Gestwicki;Jason E. Gestwicki;Laura E. Strong.
Angewandte Chemie (2006)

949 Citations

Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

Jason E. Gestwicki;Christopher W. Cairo;Laura E. Strong;Karolyn A. Oetjen.
Journal of the American Chemical Society (2002)

848 Citations

Synthetic multivalent ligands in the exploration of cell-surface interactions.

Laura L. Kiessling;Jason E Gestwicki;Laura E Strong.
Current Opinion in Chemical Biology (2000)

705 Citations

Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate.

Eric B. Bertelsen;Lyra Chang;Jason E. Gestwicki;Erik R. P. Zuiderweg.
Proceedings of the National Academy of Sciences of the United States of America (2009)

478 Citations

Control of Multivalent Interactions by Binding Epitope Density

Christopher W Cairo;Jason E Gestwicki;Motomu Kanai;Laura L Kiessling.
Journal of the American Chemical Society (2002)

450 Citations

Heat Shock Proteins 70 and 90 Inhibit Early Stages of Amyloid β-(1–42) Aggregation in Vitro

Christopher G. Evans;Susanne Wisén;Jason E. Gestwicki.
Journal of Biological Chemistry (2006)

428 Citations

Heat shock protein 70 (hsp70) as an emerging drug target.

Christopher G. Evans;Lyra Chang;Jason E. Gestwicki.
Journal of Medicinal Chemistry (2010)

392 Citations

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