2012 - Fellow of the American Association for the Advancement of Science (AAAS)
Jason E. Gestwicki focuses on Biochemistry, Cell biology, Chaperone, Receptor and Biophysics. His studies deal with areas such as Heat shock protein, Cell, Ubiquitin, Anatomy and In vivo as well as Cell biology. His Chaperone research includes themes of Neurodegeneration, Hsp70, Protein structure, Proteostasis and Allosteric regulation.
The Receptor study combines topics in areas such as Signal transduction, Ligand, Function and Effector. His work carried out in the field of Function brings together such families of science as Autophagy database, Stereochemistry, Receptor clustering and Neoplasms therapy. The study incorporates disciplines such as Extracellular, Coupling and Intracellular in addition to Stereochemistry.
Jason E. Gestwicki mainly focuses on Cell biology, Biochemistry, Chaperone, Hsp70 and Allosteric regulation. He has included themes like Heat shock protein, Neurodegeneration, Tauopathy, Alzheimer's disease and Programmed cell death in his Cell biology study. His work in Biochemistry addresses subjects such as Biophysics, which are connected to disciplines such as Receptor.
The Receptor study which covers Function that intersects with Intracellular. Jason E. Gestwicki has researched Chaperone in several fields, including Cancer research, Protein domain, Protein folding, Hsp90 and Proteostasis. His work focuses on many connections between Small molecule and other disciplines, such as Computational biology, that overlap with his field of interest in Drug discovery.
His primary scientific interests are in Cell biology, Hsp70, Chaperone, Programmed cell death and Neurodegeneration. His Cell biology study combines topics in areas such as CRISPR interference and Tauopathy. His Hsp70 study focuses on Heat shock protein and Biochemistry.
His Heat shock protein research includes themes of Protein domain, Membrane, Computational biology and Protein–protein interaction. His research in Computational biology focuses on subjects like Binding site, which are connected to Drug discovery. His studies in Chaperone integrate themes in fields like Combinatorial chemistry, Thermal stability, A protein and Effector.
Jason E. Gestwicki mainly focuses on Cell biology, Chaperone, Heat shock protein, Protein folding and Protein aggregation. His Cell biology research is multidisciplinary, relying on both Hsp70, Ubiquitin ligase, Small molecule and Tauopathy. His study looks at the relationship between Hsp70 and topics such as HSPA9, which overlap with Programmed cell death.
His Chaperone research is multidisciplinary, incorporating perspectives in Legionella pneumophila and Computational biology. As part of the same scientific family, Jason E. Gestwicki usually focuses on Computational biology, concentrating on Drug discovery and intersecting with Proteostasis. His biological study spans a wide range of topics, including Hsp90 and Multiprotein complex.
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Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Potential therapeutic applications of autophagy.
David C. Rubinsztein;Jason E. Gestwicki;Leon O. Murphy;Daniel J. Klionsky.
Nature Reviews Drug Discovery (2007)
Synthetic Multivalent Ligands as Probes of Signal Transduction
Laura L. Kiessling;Jason E. Gestwicki;Jason E. Gestwicki;Laura E. Strong.
Angewandte Chemie (2006)
Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture
Jason E. Gestwicki;Christopher W. Cairo;Laura E. Strong;Karolyn A. Oetjen.
Journal of the American Chemical Society (2002)
Synthetic multivalent ligands in the exploration of cell-surface interactions.
Laura L. Kiessling;Jason E Gestwicki;Laura E Strong.
Current Opinion in Chemical Biology (2000)
Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate.
Eric B. Bertelsen;Lyra Chang;Jason E. Gestwicki;Erik R. P. Zuiderweg.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Control of Multivalent Interactions by Binding Epitope Density
Christopher W Cairo;Jason E Gestwicki;Motomu Kanai;Laura L Kiessling.
Journal of the American Chemical Society (2002)
Heat Shock Proteins 70 and 90 Inhibit Early Stages of Amyloid β-(1–42) Aggregation in Vitro
Christopher G. Evans;Susanne Wisén;Jason E. Gestwicki.
Journal of Biological Chemistry (2006)
Heat shock protein 70 (hsp70) as an emerging drug target.
Christopher G. Evans;Lyra Chang;Jason E. Gestwicki.
Journal of Medicinal Chemistry (2010)
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