D-Index & Metrics Best Publications
Biology and Biochemistry
Argentina
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 7,555 108 World Ranking 9297 National Ranking 6

Research.com Recognitions

Awards & Achievements

2022 - Research.com Biology and Biochemistry in Argentina Leader Award

2010 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary scientific interests are in Cell biology, Glucocorticoid receptor, Hsp90, FKBP52 and Cytoplasm. His work on Dynein and Nuclear pore as part of general Cell biology research is often related to Immunophilins, thus linking different fields of science. His work deals with themes such as Heat shock protein, Molecular biology and Nitric oxide, which intersect with Glucocorticoid receptor.

His biological study spans a wide range of topics, including Plasma protein binding and Chaperone. FKBP52 is the subject of his research, which falls under Biochemistry. His Cytoplasm research is multidisciplinary, relying on both Cytoskeleton and Geldanamycin.

His most cited work include:

  • Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement. (248 citations)
  • Protein Phosphatase 5 Is a Major Component of Glucocorticoid Receptor·hsp90 Complexes with Properties of an FK506-binding Immunophilin (229 citations)
  • Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus * (207 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Hsp90, Immunophilins, Receptor and Glucocorticoid receptor. His Cell biology research is multidisciplinary, incorporating perspectives in Tetratricopeptide, Transcription factor and Heat shock protein. His Hsp90 study necessitates a more in-depth grasp of Biochemistry.

The Receptor study combines topics in areas such as Nuclear receptor and Endocrinology. His Glucocorticoid receptor study combines topics from a wide range of disciplines, such as Molecular biology and Western blot. His FKBP52 research integrates issues from Transport protein, FKBP, Nuclear pore and Bioinformatics.

He most often published in these fields:

  • Cell biology (80.77%)
  • Hsp90 (74.62%)
  • Immunophilins (54.62%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (80.77%)
  • Hsp90 (74.62%)
  • Immunophilins (54.62%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, Hsp90, Immunophilins, FKBP52 and Signal transduction. He integrates many fields in his works, including Cell biology and Trophoblast. His studies deal with areas such as Cancer research, Glucocorticoid receptor, Chaperone and Docking as well as Hsp90.

Mario D. Galigniana focuses mostly in the field of Chaperone, narrowing it down to topics relating to Receptor and, in certain cases, Nuclear receptor and Transcription factor. The concepts of his FKBP52 study are interwoven with issues in Cellular differentiation, Mechanism of action, Tetratricopeptide, Neurite and Neurotrophin. His work is dedicated to discovering how Signal transduction, Transcriptional regulation are connected with Cypa, Intracellular and Cyclophilin A and other disciplines.

Between 2018 and 2021, his most popular works were:

  • Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52 (23 citations)
  • Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52 (23 citations)
  • Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins (6 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include FKBP52, Cell biology, Immunophilins, Hsp90 and Cellular differentiation. He has researched FKBP52 in several fields, including Transport protein, Scaffold protein, Acetylation and Transcriptional regulation. Mario D. Galigniana combines subjects such as Nuclear export signal, Nuclear matrix, Tetratricopeptide, Nuclear transport and Nuclear protein with his study of Hsp90.

His studies in Cellular differentiation integrate themes in fields like Chaperone, Protein folding, Receptor, Signal transduction and Protein structure.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement.

William B Pratt;Mario D Galigniana;Jennifer M Harrell;Donald B DeFranco.
Cellular Signalling (2004)

348 Citations

Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus *

Mario D. Galigniana;Christine Radanyi;Jack Michel Renoir;Paul R. Housley.
Journal of Biological Chemistry (2001)

314 Citations

Role of molecular chaperones in steroid receptor action.

William B Pratt;Mario D Galigniana;Yoshihiro Morishima;Patrick J M Murphy.
Essays in Biochemistry (2004)

307 Citations

Protein Phosphatase 5 Is a Major Component of Glucocorticoid Receptor·hsp90 Complexes with Properties of an FK506-binding Immunophilin

Adam M. Silverstein;Mario D. Galigniana;Mei-Shya Chen;Janet K. Owens-Grillo.
Journal of Biological Chemistry (1997)

296 Citations

A model for the cytoplasmic trafficking of signalling proteins involving the hsp90-binding immunophilins and p50cdc37.

William B Pratt;Adam M Silverstein;Mario D Galigniana.
Cellular Signalling (1999)

232 Citations

Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein.

Adam M. Silverstein;Mario D. Galigniana;Kimon C. Kanelakis;Christine Radanyi.
Journal of Biological Chemistry (1999)

232 Citations

Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton

Mario D. Galigniana;Jennifer L. Scruggs;James Herrington;Michael J. Welsh.
Molecular Endocrinology (1998)

229 Citations

FKBP51 and FKBP52 in Signaling and Disease

Cheryl L. Storer;Chad A. Dickey;Mario Daniel Galigniana;Theo Rein.
Trends in Endocrinology and Metabolism (2011)

223 Citations

The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.

Kurt D. Dittmar;Maria Banach;Mario D. Galigniana;William B. Pratt.
Journal of Biological Chemistry (1998)

218 Citations

Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus.

Michael J. Czar;Mario D. Galigniana;and Adam M. Silverstein;William B. Pratt.
Biochemistry (1997)

200 Citations

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