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Biology and Biochemistry
Argentina
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
7884
World Ranking
18081
National Ranking
23

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Argentina Leader Award
  • 2022 - Research.com Biology and Biochemistry in Argentina Leader Award
  • 2010 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Mario D. Galigniana is affiliated with the Experimental Medicine and Biology Institute in Argentina. Their main research contributions lie within the field of Biochemistry, Genetics, and Molecular Biology, with particular emphasis on Molecular Biology, Immunology, Genetics, Endocrinology, Diabetes and Metabolism, and Cell Biology.

The scientist's work extensively covers topics such as Heat shock proteins research, Signaling Pathways in Disease, Toxin Mechanisms and Immunotoxins, Estrogen and related hormone effects, Hormonal Regulation and Hypertension, Endoplasmic Reticulum Stress and Disease, and Cell death mechanisms and regulation.

Frequent publication venues for Mario D. Galigniana include the Journal of Cell Science, Biochemical Pharmacology, Journal of Cellular Biochemistry, Trends in Endocrinology and Metabolism, and Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.

Frequent co-authors have included:

  • Gisela I. Mazaira
  • Cristina Daneri-Becerra
  • Nadia R. Zgajnar
  • Luciana I. Gallo
  • Mariana Lagadari

Notable recent papers authored or co-authored by Mario D. Galigniana include:

  • "Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins" (2020, Journal of Cell Science)
  • "Cyclophilin A is a mitochondrial factor that forms complexes with p23 - correlative evidence for an anti-apoptotic action" (2020, Journal of Cell Science)
  • "Proof that the high molecular weight immunophilin FKBP52 mediates the in vivo neuroregenerative effect of the macrolide FK506" (2020, Biochemical Pharmacology)
  • "Corticosteroid receptors as a model for the Hsp90•immunophilin-based transport machinery" (2021, Trends in Endocrinology and Metabolism)
  • "Differential regulation of the glucocorticoid receptor nucleocytoplasmic shuttling by TPR-domain proteins" (2021, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research)

Mario D. Galigniana was awarded the Fellowship of the John Simon Guggenheim Memorial Foundation in 2010.

Best Publications

  • Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement.

    William B Pratt;Mario D Galigniana;Jennifer M Harrell;Donald B DeFranco

  • Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus *

    Mario D. Galigniana;Christine Radanyi;Jack Michel Renoir;Paul R. Housley

  • Role of molecular chaperones in steroid receptor action.

    William B Pratt;Mario D Galigniana;Yoshihiro Morishima;Patrick J M Murphy

  • Protein Phosphatase 5 Is a Major Component of Glucocorticoid Receptor·hsp90 Complexes with Properties of an FK506-binding Immunophilin

    Adam M. Silverstein;Mario D. Galigniana;Mei-Shya Chen;Janet K. Owens-Grillo

  • FKBP51 and FKBP52 in Signaling and Disease

    Cheryl L. Storer;Chad A. Dickey;Mario Daniel Galigniana;Theo Rein

  • Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein.

    Adam M. Silverstein;Mario D. Galigniana;Kimon C. Kanelakis;Christine Radanyi

  • Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton

    Mario D. Galigniana;Jennifer L. Scruggs;James Herrington;Michael J. Welsh

  • A model for the cytoplasmic trafficking of signalling proteins involving the hsp90-binding immunophilins and p50cdc37.

    William B Pratt;Adam M Silverstein;Mario D Galigniana

  • The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.

    Kurt D. Dittmar;Maria Banach;Mario D. Galigniana;William B. Pratt

  • Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.

    Mario D. Galigniana;Jennifer M. Harrell;Heather M. O'Hagen;Mats Ljungman

  • Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus.

    Michael J. Czar;Mario D. Galigniana;and Adam M. Silverstein;William B. Pratt

  • Inhibition of glucocorticoid receptor binding by nitric oxide

    Mario D. Galigniana;Graciela Piwien-Pilipuk;Jamil Assreuy

  • Nuclear Import of the Glucocorticoid Receptor-hsp90 Complex through the Nuclear Pore Complex Is Mediated by Its Interaction with Nup62 and Importin β

    Pablo C. Echeverría;Gisela Mazaira;Alejandra Erlejman;Celso Gomez-Sanchez

  • The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events.

    Mario D. Galigniana;Mario D. Galigniana;Alejandra G. Erlejman;Martín Monte;Celso Gomez-Sanchez

  • Evidence for Glucocorticoid Receptor Transport on Microtubules by Dynein

    Jennifer M. Harrell;Patrick J.M. Murphy;Yoshihiro Morishima;Haifeng Chen

  • Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain.

    Mario D. Galigniana;Jennifier M. Harrell;Patrick J.M. Murphy;Michael David Chinkers

  • The 90-kDa Heat-shock Protein (Hsp90)-binding Immunophilin FKBP51 Is a Mitochondrial Protein That Translocates to the Nucleus to Protect Cells against Oxidative Stress

    Luciana I. Gallo;Mariana Lagadari;Graciela Piwien-Pilipuk;Mario D. Galigniana;Mario D. Galigniana

  • Pifithrin-α Inhibits p53 Signaling after Interaction of the Tumor Suppressor Protein with hsp90 and Its Nuclear Translocation

    Patrick J. Murphy;Mario Daniel Galigniana;Yoshihiro Morishima;Jennifer M. Harrell

  • Differential responsivity of the hypothalamic-pituitary-adrenal axis to glucocorticoid negative-feedback and corticotropin releasing hormone in rats undergoing morphine withdrawal: Possible mechanisms involved in facilitated and attenuated stress responses

    H. Houshyar;M. D. Galigniana;W. B. Pratt;J. H. Woods

  • Review article Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement

    William B. Pratt;Mario D. Galigniana;Jennifer M. Harrell;Donald B. DeFranco

Frequent Co-Authors

William B. Pratt
William B. Pratt University of Michigan–Ann Arbor
Celso E. Gomez-Sanchez
Celso E. Gomez-Sanchez University of Mississippi Medical Center
Donald B. DeFranco
Donald B. DeFranco University of Pittsburgh
Mats Ljungman
Mats Ljungman University of Michigan–Ann Arbor
Shinichi Takayama
Shinichi Takayama Sanford Burnham Prebys Medical Discovery Institute
Michael J. Welsh
Michael J. Welsh University of Michigan–Ann Arbor
John C. Reed
John C. Reed Johnson & Johnson (United States)
David O. Toft
David O. Toft Mayo Clinic
Gerald Litwack
Gerald Litwack Texas A&M Health Science Center
Christin Carter-Su
Christin Carter-Su University of Michigan–Ann Arbor

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