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Biology and Biochemistry

D-Index
52
Citations
31943
World Ranking
16407
National Ranking
1149

Overview

Theo Rein is affiliated with the Max Planck Society in Germany, contributing extensively to the field of biochemistry, genetics, and molecular biology. Their research spans molecular biology, behavioral neuroscience, plant science, health, toxicology, mutagenesis, and biological psychiatry.

Their work covers several interconnected topics, including:

  • Stress Responses and Cortisol
  • Signaling Pathways in Disease
  • Heat Shock Proteins Research
  • Pesticide Exposure and Toxicity
  • Tryptophan and Brain Disorders
  • Endoplasmic Reticulum Stress and Disease
  • Noise Effects and Management

The scientist's publication record includes papers in notable venues such as Molecular Psychiatry, Journal of Cellular Biochemistry, Archives of Toxicology, BioEssays, and Biochemical Society Transactions. Frequent collaborators include Wolfgang Schmeißer, Horst Thiermann, Harald John, Gabriel R. Fries, and Nils C. Gassen.

Selected recent publications by Theo Rein include:

  • Peptidylprolylisomerases, Protein Folders, or Scaffolders? The Example of FKBP51 and FKBP52, 2020, BioEssays
  • Post-translational modifications and stress adaptation: the paradigm of FKBP51, 2020, Biochemical Society Transactions
  • Molecular pathways of major depressive disorder converge on the synapse, 2022, Molecular Psychiatry
  • Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity, 2022, Molecular Psychiatry
  • Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans, 2021, Neurobiology of Stress

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions

    Torsten Klengel;Divya Mehta;Christoph Anacker;Monika Rex-Haffner

  • Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

    Elisabeth B Binder;Daria Salyakina;Peter Lichtner;Gabriele M Wochnik

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells

    Gabriela M. Wochnik;Joëlle Rüegg;G. Alexander Abel;Ulrike Schmidt

  • Identifying 5-methylcytosine and related modifications in DNA genomes

    Theo Rein;Melvin L. DePamphilis;Haralabos Zorbas

  • Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks

    Rachel Yehuda;Guiqing Cai;Julia A. Golier;Casey Sarapas

  • Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.

    Anthony S. Zannas;Meiwen Jia;Kathrin Hafner;Jens Baumert

  • SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

    Nils C. Gassen;Daniela Niemeyer;Doreen Muth;Victor M. Corman

  • FKBP51 and FKBP52 in Signaling and Disease

    Cheryl L. Storer;Chad A. Dickey;Mario Daniel Galigniana;Theo Rein

  • FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior

    Chadi Touma;Nils Christian Gassen;Leonie Herrmann;Joyce Cheung-Flynn

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.

    Jakob Hartmann;Klaus V. Wagner;Claudia Liebl;Sebastian H. Scharf

  • Identification of Primary Initiation Sites for DNA Replication in the Hamster Dihydrofolate Reductase Gene Initiation Zone

    Takehiko Kobayashi;Theo Rein;Melvin L. DePamphilis

  • Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

    Nils C. Gassen;Jakob Hartmann;Jürgen Zschocke;Jens Stepan

  • Cross-talk of vitamin D and glucocorticoids in hippocampal cells

    Darja Obradovic;Hinrich Gronemeyer;Beat Lutz;Theo Rein

  • Genetic Markers for PTSD Risk and Resilience Among Survivors of the World Trade Center Attacks

    Casey Sarapas;Guiqing Cai;Linda M. Bierer;Julia A. Golier

  • The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction

    Ana Clara Liberman;Damian Refojo;Jimena Druker;Marta Alicia Toscano

  • Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.

    T Rein;H Zorbas;M L DePamphilis

Frequent Co-Authors

Florian Holsboer
Florian Holsboer Max Planck Institute of Psychiatry
Marianne B. Müller
Marianne B. Müller Johannes Gutenberg University of Mainz
Elisabeth B. Binder
Elisabeth B. Binder Max Planck Society
Manfred Uhr
Manfred Uhr Max Planck Society
Bertram Müller-Myhsok
Bertram Müller-Myhsok Max Planck Society
Rainer Rupprecht
Rainer Rupprecht University of Regensburg
Jan M. Deussing
Jan M. Deussing Max Planck Society
Gabriel R. Fries
Gabriel R. Fries The University of Texas Health Science Center at Houston
Marcus Ising
Marcus Ising Max Planck Society
Kerry J. Ressler
Kerry J. Ressler Harvard University

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