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Medicine

D-Index
87
Citations
29092
World Ranking
13598
National Ranking
727

Overview

Manfred Uhr is affiliated with the Max Planck Society in Germany. Their research spans across several fields, primarily focusing on medicine and neuroscience. Within these domains, they have contributed substantially to areas such as pharmacology, psychiatry and mental health, cognitive neuroscience, biological psychiatry, and behavioral neuroscience.

The scientist's work addresses several key topics, including:

  • Tryptophan and brain disorders
  • Stress responses and cortisol
  • Sleep and wakefulness research
  • Circadian rhythm and melatonin
  • Treatment of major depression
  • Sleep and related disorders
  • Schizophrenia research and treatment

Manfred Uhr has published in various journals, frequently appearing in:

  • Psychoneuroendocrinology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Pharmacopsychiatry
  • JAMA Network Open
  • Neurological Research and Practice

Recent papers include:

  • Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression, 2022, JAMA Network Open
  • S1 guidelines "lumbar puncture and cerebrospinal fluid analysis" (abridged and translated version), 2020, Neurological Research and Practice
  • Effects of weariness of life, suicide ideations and suicide attempt on HPA axis regulation in depression, 2021, Psychoneuroendocrinology
  • Effects of Pharmacokinetic Gene Variation on Therapeutic Drug Levels and Antidepressant Treatment Response, 2022, Pharmacopsychiatry
  • Donepezil, a cholinesterase inhibitor used in Alzheimer's disease therapy, is actively exported out of the brain by abcb1ab p-glycoproteins in mice, 2020, Journal of Psychiatric Research

The scientist frequently collaborates with other researchers, including:

  • Axel Steiger
  • Marcus Ising
  • Herta Flor
  • Jens Wiltfang
  • Hayrettin Tumani

Best Publications

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017.

    C. Hiemke;N. Bergemann;H. W. Clement;A. Conca

  • A mega-analysis of genome-wide association studies for major depressive disorder

    Stephan Ripke;Naomi R Wray;Cathryn M Lewis;Steven P Hamilton

  • Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

    Elisabeth B Binder;Daria Salyakina;Peter Lichtner;Gabriele M Wochnik

  • AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011

    C. Hiemke;P. Baumann;N. Bergemann;A. Conca

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression. a prospective study.

    Astrid W. Zobel;Thomas Nickel;Annette Sonntag;Manfred Uhr

  • Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease

    Jens Wagner;Sergey Ryazanov;Sergey Ryazanov;Andrei Leonov;Andrei Leonov;Johannes Levin

  • Polymorphisms in the drug transporter Gene ABCB1 predict antidepressant treatment response in depression

    Manfred Uhr;Alina Tontsch;Christian Namendorf;Stephan Ripke

  • Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?

    Marcus Ising;Sonja Horstmann;Stefan Kloiber;Susanne Lucae

  • The Role of m6A/m-RNA Methylation in Stress Response Regulation

    Mareen Engel;Carola Eggert;Paul M. Kaplick;Matthias Eder

  • Ghrelin promotes slow-wave sleep in humans.

    Jutta C. Weikel;Adam Wichniak;Marcus Ising;Hans Brunner

  • Body Weight and Leptin Plasma Levels During Treatment With Antipsychotic Drugs

    T. Kraus;M. Haack;A. Schuld;D. Hinze-Selch

  • Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls.

    Marcus Ising;Anna-Mareike Depping;Anna Siebertz;Susanne Lucae

  • A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression

    Marcus Ising;Susanne Lucae;Elisabeth B. Binder;Thomas Bettecken

  • Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study.

    Petra Zimmermann;Tanja Brückl;Agnes Nocon;Hildegard Pfister

  • P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder

    Susanne Lucae;Daria Salyakina;Nicholas Barden;Mario Harvey

  • Penetration of Amitriptyline, but Not of Fluoxetine, into Brain is Enhanced in Mice with Blood-Brain Barrier Deficiency Due to Mdr1a P-Glycoprotein Gene Disruption

    Manfred Uhr;Thomas Steckler;Alexander Yassouridis;Florian Holsboer

  • AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: update 2011

    C Hiemke;P Baumann;N Bergemann;O Dietmaier

  • A mega-analysis of genome-wide association studies for major depressive disorder

    S. Ripke;N. R. Wray;C. M. Lewis;S. P. Hamilton

Frequent Co-Authors

Florian Holsboer
Florian Holsboer Max Planck Institute of Psychiatry
Marcus Ising
Marcus Ising Max Planck Society
Elisabeth B. Binder
Elisabeth B. Binder Max Planck Society
Bertram Müller-Myhsok
Bertram Müller-Myhsok Max Planck Society
Axel Steiger
Axel Steiger Max Planck Society
Alexander Yassouridis
Alexander Yassouridis Max Planck Society
Stephan Ripke
Stephan Ripke Massachusetts General Hospital
Theo Rein
Theo Rein Max Planck Society
Roselind Lieb
Roselind Lieb University of Basel
Mathias V. Schmidt
Mathias V. Schmidt Max Planck Society

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