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Molecular Biology

D-Index
69
Citations
14926
World Ranking
1484
National Ranking
754

Overview

Martin Sattler is affiliated with Harvard University in the United States and conducts research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans various subfields, including Molecular Biology, Oncology, Hematology, Pulmonary and Respiratory Medicine, and Immunology.

Sattler's research topics focus on:

  • Protein Degradation and Inhibitors
  • Multiple Myeloma Research and Treatments
  • Peptidase Inhibition and Analysis
  • Lung Cancer Treatments and Mutations
  • Ubiquitin and proteasome pathways
  • Acute Myeloid Leukemia Research
  • COVID-19 and healthcare impacts

Recent publications by Sattler include:

  • "BindingDB Entry 50022503: A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase." (2025, PubMed)
  • "The improbable targeted therapy: KRAS as an emerging target in non-small cell lung cancer (NSCLC)" (2021, Cell Reports Medicine)
  • "Repurposing of Kinase Inhibitors for Treatment of COVID-19" (2020, Pharmaceutical Research)
  • "The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping" (2020, Cancer Treatment Reviews)
  • "General practitioners' deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries" (2021, BMC Geriatrics)

Frequent co-authors collaborating with Sattler are:

  • Ravi Salgia
  • Ellen Weisberg
  • James D. Griffin
  • Chengcheng Meng
  • Richard M. Stone

Notable publication venues where Sattler has contributed multiple papers include:

  • Leukemia
  • Cancers
  • Cell Reports Medicine
  • Blood Cancer Journal
  • British Journal of Cancer

Best Publications

  • Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration

    Klaus Podar;Yu-Tzu Tai;Faith E. Davies;Suzanne Lentzsch

  • Critical role for Gab2 in transformation by BCR/ABL

    Martin Sattler;M.Golam Mohi;Yuri B Pride;Laura R Quinnan

  • The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells

    Martin Sattler;Shalini Verma;Gautam Shrikhande;Christopher H. Byrne

  • Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia

    Akinori Yoda;Yuka Yoda;Sabina Chiaretti;Michal Bar-Natan

  • Regulation of Cellular Proliferation, Cytoskeletal Function, and Signal Transduction through CXCR4 and c-Kit in Small Cell Lung Cancer Cells

    Takashi Kijima;Gautam Maulik;Patrick Chi-Chung Ma;Elena V. Tibaldi

  • The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.

    Martin Sattler;Ravi Salgia;Keiko Okuda;Naoki Uemura

  • Hematopoietic growth factors signal through the formation of reactive oxygen species.

    Martin Sattler;Thomas Winkler;Shalini Verma;Christopher H. Byrne

  • STAT5 activation contributes to growth and viability in Bcr/Abl-transformed cells

    Christian Sillaber;Franck Gesbert;David A. Frank;Martin Sattler

  • Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species.

    Jeong H. Kim;Stephanie C. Chu;Stephanie C. Chu;Stephanie C. Chu;Jessica L. Gramlich;Jessica L. Gramlich;Jessica L. Gramlich;Yuri B. Pride;Yuri B. Pride;Yuri B. Pride

  • The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma

    Klaus Podar;Giovanni Tonon;Martin Sattler;Yu Tsu Tai

  • Vascular Endothelial Growth Factor-induced Migration of Multiple Myeloma Cells Is Associated with β1 Integrin- and Phosphatidylinositol 3-Kinase-dependent PKCα Activation

    Klaus Podar;Yu-Tzu Tai;Boris K. Lin;Radha P. Narsimhan

  • Molecular mechanisms of transformation by the BCR-ABL oncogene.

    Martin Sattler;James D Griffin

  • BCR/ABL induces multiple abnormalities of cytoskeletal function.

    R. Salgia;J.-L. Li;D. S. Ewaniuk;W. Pear

  • Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells.

    Klaus Podar;Yu Tzu Tai;Craig E. Cole;Craig E. Cole;Teru Hideshima

  • Ethnic Differences and Functional Analysis of MET Mutations in Lung Cancer

    Soundararajan Krishnaswamy;Rajani Kanteti;Jonathan S. Duke-Cohan;Sivakumar Loganathan

  • Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

    Margaret Nieborowska-Skorska;Piotr K. Kopinski;Regina Ray;Grazyna Hoser

  • The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.

    M. Sattler;M. A. Durstin;D. A. Frank;K. Okuda

  • CRKL Links p210BCR/ABL with Paxillin in Chronic Myelogenous Leukemia Cells

    Ravi Salgia;Naoki Uemura;Keiko Okuda;Jian-Liang Li

  • 2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells

    Dharminder Chauhan;Laurence Catley;Teru Hideshima;Guilan Li

  • The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes.

    Gerlinde Wernig;Jeffrey R. Gonneville;Brian J. Crowley;Margret S. Rodrigues;Margret S. Rodrigues

Frequent Co-Authors

James D. Griffin
James D. Griffin Harvard University
Ravi Salgia
Ravi Salgia City Of Hope National Medical Center
Klaus Podar
Klaus Podar Karl Landsteiner University of Health Sciences
Ellen Weisberg
Ellen Weisberg Harvard University
Dharminder Chauhan
Dharminder Chauhan Harvard University
Teru Hideshima
Teru Hideshima Harvard University
Nathanael S. Gray
Nathanael S. Gray Stanford University
Yu-Tzu Tai
Yu-Tzu Tai Harvard University
Richard Stone
Richard Stone Harvard University
Kenneth C. Anderson
Kenneth C. Anderson Harvard University

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