William Lehman

Overview

Best Publications

• Steric-model for activation of muscle thin filaments

  Peter Vibert;Roger Craig;William Lehman

  556
  Citations

• Regulation in molluscan muscles

  John Kendrick-Jones;William Lehman;Andrew G. Szent-Györgyi

  489
  Citations

• Regulation of muscular contraction. Distribution of actin control and myosin control in the animal kingdom.

  William Lehman;Andrew G. Szent-Gyorgyi

  467
  Citations

• Ca 2+ -induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction

  William Lehman;Roger Craig;Peter Vibert

  432
  Citations

• Structure of the F-actin–tropomyosin complex

  Julian von der Ecken;Mirco Müller;William Lehman;Dietmar J. Manstein

  402
  Citations

• Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments.

  William Lehman;Victoria Hatch;Vicci Korman;Michael Rosol

  295
  Citations

• Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy.

  C. Xu;R. Craig;L. Tobacman;R. Horowitz

  224
  Citations

• Steric-blocking by tropomyosin visualized in relaxed vertebrate muscle thin filaments.

  William Lehman;Peter Vibert;Pedro Uman;Roger Craig

  213
  Citations

• Structural basis for the regulation of muscle contraction by troponin and tropomyosin.

  Agnieszka Galinska-Rakoczy;Patti Engel;Chen Xu;HyunSuk Jung

  206
  Citations

• A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle.

  Katrina J. V. Poole;Michael Lorenz;Gwyndaf Evans;Gerd Rosenbaum

  189
  Citations

• Tropomyosin Position on F-Actin Revealed by EM Reconstruction and Computational Chemistry

  Xiachuan Edward Li;Xiachuan Edward Li;Larry S. Tobacman;Ji Young Mun;Roger W. Craig

  185
  Citations

• Caldesmon is a Ca2+-regulatory component of native smooth-muscle thin filaments.

  S B Marston;W Lehman

  184
  Citations

• Crossbridge and tropomyosin positions observed in native, interacting thick and thin filaments.

  Roger Craig;William Lehman

  178
  Citations

• Myosin-linked Regulatory Systems: Comparative Studies

  William Lehman;John Kendrick-Jones;Andrew G. Szent-Györgyi

  175
  Citations

• An atomic model of fimbrin binding to F-actin and its implications for filament crosslinking and regulation

  Dorit Hanein;Niels Volkmann;Sharon Goldsmith;Anne-Marie Michon

  167
  Citations

• An atomic model of the thin filament in the relaxed and Ca2+-activated states.

  Alnoor Pirani;Maia V. Vinogradova;Paul M.G. Curmi;William A. King

  165
  Citations

• Gestalt-binding of tropomyosin to actin filaments.

  Kenneth C. Holmes;William Lehman

  151
  Citations

• The Troponin Tail Domain Promotes a Conformational State of the Thin Filament That Suppresses Myosin Activity

  Larry S. Tobacman;Mahta Nihli;Carol Butters;Mark Heller

  139
  Citations

• The shape and flexibility of tropomyosin coiled coils: implications for actin filament assembly and regulation

  Xiaochuan Edward Li;Kenneth C. Holmes;William Lehman;Hyun Suk Jung

  139
  Citations

• Single particle analysis of relaxed and activated muscle thin filaments.

  Alnoor Pirani;Chen Xu;Victoria Hatch;Roger W. Craig

  138
  Citations