H-Index & Metrics Best Publications
Edna C. Hardeman

Edna C. Hardeman

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 10,341 119 World Ranking 9229 National Ranking 260

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Edna C. Hardeman mostly deals with Cell biology, Skeletal muscle, Myocyte, Molecular biology and Gene. Edna C. Hardeman is interested in Tropomyosin, which is a branch of Cell biology. Her Skeletal muscle research is multidisciplinary, relying on both Muscle hypertrophy, Gene expression and Myopathy.

The study incorporates disciplines such as Regulation of gene expression and Myosin in addition to Myocyte. The concepts of her Molecular biology study are interwoven with issues in Myogenesis and Transgene. Her Gene research incorporates themes from Actinin and Muscle contraction.

Her most cited work include:

  • Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models (1251 citations)
  • Plasticity of the differentiated state. (716 citations)
  • Tropomyosin-Based Regulation of the Actin Cytoskeleton in Time and Space (366 citations)

What are the main themes of her work throughout her whole career to date?

Edna C. Hardeman mainly investigates Cell biology, Actin, Skeletal muscle, Tropomyosin and Actin cytoskeleton. Her Cell biology study combines topics from a wide range of disciplines, such as Cell, Cytoskeleton and Actin remodeling. Her Actin research incorporates elements of Phenotype, Protein filament, Pathology, Motility and Gene isoform.

Edna C. Hardeman has included themes like Myocyte, Molecular biology and Gene expression in her Skeletal muscle study. Her Tropomyosin study combines topics in areas such as Cancer research, Cell migration and In vivo. Her Actin cytoskeleton study integrates concerns from other disciplines, such as Cancer cell, Filamentous actin, Cell growth and Tumor cells.

She most often published in these fields:

  • Cell biology (51.45%)
  • Actin (41.04%)
  • Skeletal muscle (39.88%)

What were the highlights of her more recent work (between 2016-2021)?

  • Actin (41.04%)
  • Tropomyosin (32.37%)
  • Cell biology (51.45%)

In recent papers she was focusing on the following fields of study:

Edna C. Hardeman spends much of her time researching Actin, Tropomyosin, Cell biology, Actin cytoskeleton and Cytoskeleton. Her Actin research includes themes of Microtubule, Protein filament, Actin remodeling and Gene isoform. Her Tropomyosin research integrates issues from Actin-binding protein, Cancer research and Mitosis.

The various areas that Edna C. Hardeman examines in her Cell biology study include Transcriptome and Stromal cell. Her research in Actin cytoskeleton intersects with topics in Cancer, Cell migration, Focal adhesion, Phenotype and Mutant. Edna C. Hardeman has researched Cytoskeleton in several fields, including Cancer cell, Contractility and Nemaline myopathy.

Between 2016 and 2021, her most popular works were:

  • A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts (47 citations)
  • Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia (36 citations)
  • Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton (32 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Actin, Tropomyosin, Actin cytoskeleton, Cell biology and Gene isoform are her primary areas of study. Her Tropomyosin study incorporates themes from In vivo, Pharmacology and Cytoskeleton. Her biological study spans a wide range of topics, including Skeletal muscle, Carbohydrate metabolism, Glucose uptake and Cortical actin cytoskeleton.

Her study explores the link between Actin cytoskeleton and topics such as Cancer that cross with problems in Computational biology, Druggability, Phenotypic screening, Chemical biology and Phenotype. Her primary area of study in Cell biology is in the field of Myosin. Her research investigates the connection with Gene isoform and areas like Protein filament which intersect with concerns in Cytochalasin D, Exocytosis, Acetylation, Biophysics and Tropomyosin binding.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner;Yazi D. Ke;Fabien Delerue;Mian Bi.
Cell (2010)

1585 Citations

Plasticity of the differentiated state.

Helen M. Blau;Grace K. Pavlath;Edna C. Hardeman;Choy-Pik Chiu.
Science (1985)

987 Citations

Tropomyosin-Based Regulation of the Actin Cytoskeleton in Time and Space

Peter Gunning;Geraldine O’neill;Edna Hardeman.
Physiological Reviews (2008)

456 Citations

Tropomyosin isoforms: divining rods for actin cytoskeleton function.

Peter W. Gunning;Galina Schevzov;Anthony J. Kee;Edna C. Hardeman.
Trends in Cell Biology (2005)

356 Citations

Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans.

Daniel MacArthur;Jane T Seto;Jane T Seto;Joanna M Raftery;Kate G Quinlan;Kate G Quinlan.
Nature Genetics (2007)

319 Citations

An Actn3 knockout mouse provides mechanistic insights into the association between α-actinin-3 deficiency and human athletic performance

Daniel G. MacArthur;Jane T. Seto;Stephen Chan;Kate G.R. Quinlan.
Human Molecular Genetics (2008)

302 Citations

Targeted selection of recombinant clones through gene dosage effects.

Jasper Rine;William Hansen;Edna Hardeman;Ronald W. Davis.
Proceedings of the National Academy of Sciences of the United States of America (1983)

294 Citations

Transcription occurs in pulses in muscle fibers

S. Newlands;L. K. Levitt;C. S. Robinson;A. B. C. Karpf.
Genes & Development (1998)

270 Citations

Specification of Actin Filament Function and Molecular Composition by Tropomyosin Isoforms

Nicole S. Bryce;Galina Schevzov;Vicki Ferguson;Justin M. Percival.
Molecular Biology of the Cell (2003)

254 Citations

Quantitative analysis of the human alpha-skeletal actin gene in transgenic mice.

K.J. Brennan;E.C. Hardeman.
Journal of Biological Chemistry (1993)

246 Citations

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