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Gregory J. Cooney

Gregory J. Cooney

D-Index & Metrics

Medicine

D-Index
82
Citations
23861
World Ranking
16154
National Ranking
538

Overview

Gregory J. Cooney is affiliated with the University of Sydney in Australia. Their research spans several interconnected fields, focusing primarily on metabolism, biochemistry, and molecular biology within medical science.

The scientist's main fields of study include Medicine and Biochemistry, Genetics and Molecular Biology. Their work often addresses subfields such as Physiology, Molecular Biology, Surgery, Epidemiology, and Biochemistry.

Key research topics in their portfolio cover the following areas:

  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • Pancreatic function and diabetes
  • Mitochondrial Function and Pathology
  • Metabolism, Diabetes, and Cancer
  • Lipid metabolism and biosynthesis
  • Diet, Metabolism, and Disease

Notable recent papers authored or co-authored by Gregory J. Cooney include:

  • Branched chain amino acids, aging and age-related health (2020), published in Ageing Research Reviews
  • Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice (2020), published in Nature Communications
  • Impact of dietary carbohydrate type and protein-carbohydrate interaction on metabolic health (2021), published in Nature Metabolism
  • Systems-level analysis of insulin action in mouse strains provides insight into tissue- and pathway-specific interactions that drive insulin resistance (2022), published in Cell Metabolism
  • Nutritional reprogramming of mouse liver proteome is dampened by metformin, resveratrol, and rapamycin (2021), published in Cell Metabolism

Frequent collaborators in the scientist's work include:

  • Amanda E. Brandon
  • David E. James
  • Kristen C. Cooke
  • Mark Larance
  • Stephen J. Simpson

Gregory J. Cooney has published consistently in a range of academic venues with multiple papers in each, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism
  • Journal of Biological Chemistry
  • iScience
  • eLife

Best Publications

  • Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle *

    Chunli Yu;Yan Chen;Gary W. Cline;Dongyan Zhang

  • The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice.

    Samantha M. Solon-Biet;Aisling C. McMahon;J. William O. Ballard;Kari Ruohonen

  • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents.

    Nigel Turner;Clinton R. Bruce;Susan M. Beale;Kyle L. Hoehn

  • Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I: A Mechanism for the Action of Berberine to Activate AMP-Activated Protein Kinase and Improve Insulin Action

    Nigel Turner;Jing Ya Li;Alison Gosby;Sabrina W.C. To

  • Insulin resistance is a cellular antioxidant defense mechanism

    Kyle L Hoehn;Adam B Salmon;Cordula Hohnen-Behrens;Nigel Turner

  • Mechanisms of Liver and Muscle Insulin Resistance Induced by Chronic High-Fat Feeding

    Nicholas D Oakes;Gregory J Cooney;Souad Camilleri;Donald J Chisholm

  • Dietary fats and insulin action

    L. H. Storlien;L. A. Baur;A. D. Kriketos;D. A. Pan;D. A. Pan

  • Peroxisome Proliferator—Activated Receptor (PPAR)-α Activation Lowers Muscle Lipids and Improves Insulin Sensitivity in High Fat—Fed Rats Comparison With PPAR-γ Activation

    Ji-Ming Ye;Patrick J. Doyle;Miguel A. Iglesias;David G. Watson

  • Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

    Nigel Turner;Nigel Turner;Grzegorz Kowalski;Grzegorz Kowalski;Simon J Leslie;Steve Risis

  • Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding

    Magdalene K Montgomery;Nicole L Hallahan;Simon H J Brown;Menghan Liu

  • Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance.

    Clinton R Bruce;Andrew James Hoy;Nigel Turner;Matthew James Watt

  • An Actn3 knockout mouse provides mechanistic insights into the association between α-actinin-3 deficiency and human athletic performance

    Daniel G. MacArthur;Jane T. Seto;Stephen Chan;Kate G.R. Quinlan

  • Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle

    Bronwyn A. Ellis;Ann Poynten;Andrew J. Lowy;Stuart M. Furler

  • AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats

    Miguel A. Iglesias;Ji-Ming Ye;Georgia Frangioudakis;Asish K. Saha

  • The role of intramuscular lipid in insulin resistance

    Bronwyn D Hegarty;Stuart M Furler;J M Ye;G J Cooney

  • Insulin-like growth factor-binding protein-1 modulates blood glucose levels.

    Lewitt Ms;Denyer Gs;Cooney Gj;Baxter Rc

  • Muscle Oxidative Capacity Is a Better Predictor of Insulin Sensitivity than Lipid Status

    Clinton R. Bruce;Mitchell J. Anderson;Andrew L. Carey;David G. Newman

  • Free fatty acids and skeletal muscle insulin resistance.

    Edward W Kraegen;Gregory J Cooney

  • Branched chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control.

    Samantha M Solon-Biet;Victoria C Cogger;Tamara Pulpitel;Devin Wahl;Devin Wahl

  • Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with Type 2 diabetes

    C. R. Bruce;A. D. Kriketos;G. J. Cooney;J. A. Hawley

Frequent Co-Authors

Nigel Turner
Nigel Turner University of New South Wales
Edward W. Kraegen
Edward W. Kraegen Garvan Institute of Medical Research
David E. James
David E. James University of Sydney
David G. Le Couteur
David G. Le Couteur University of Sydney
Trevor J. Biden
Trevor J. Biden Garvan Institute of Medical Research
Kathryn N. North
Kathryn N. North University of Melbourne
Stephen J. Simpson
Stephen J. Simpson University of Sydney
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
Neil B. Ruderman
Neil B. Ruderman Boston University
Eric A. Newsholme
Eric A. Newsholme University of Oxford

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