Member of the Association of American Physicians
The scientist’s investigation covers issues in Internal medicine, Endocrinology, AMPK, Protein kinase A and AMP-activated protein kinase. His Internal medicine study frequently draws connections between adjacent fields such as Diabetes mellitus. His Endocrinology study frequently links to related topics such as Acetyl-CoA carboxylase.
His AMPK research is multidisciplinary, incorporating perspectives in Calorie restriction, Malonyl Coenzyme A, Sirtuin 1 and Cell growth. His research in Protein kinase A focuses on subjects like Protein deacetylase, which are connected to Kinase activity, Anabolism and Catabolism. His studies deal with areas such as Adiponectin, Enzyme activator, Protein kinase B and Umbilical vein as well as AMP-activated protein kinase.
Neil B. Ruderman mainly focuses on Internal medicine, Endocrinology, Insulin, Skeletal muscle and AMPK. Many of his studies involve connections with topics such as Diabetes mellitus and Internal medicine. The study incorporates disciplines such as AMP-activated protein kinase, Acetyl-CoA carboxylase and Biochemistry in addition to Endocrinology.
His Insulin research incorporates themes from Carbohydrate metabolism and Stimulation. His work on Soleus muscle is typically connected to In vivo as part of general Skeletal muscle study, connecting several disciplines of science. His AMPK study integrates concerns from other disciplines, such as Protein kinase B and Lipid metabolism.
His primary areas of investigation include Internal medicine, Endocrinology, AMPK, AMP-activated protein kinase and Insulin resistance. His Internal medicine study often links to related topics such as Diabetes mellitus. His study focuses on the intersection of Endocrinology and fields such as Sirtuin 1 with connections in the field of Calorie restriction.
His AMPK study incorporates themes from Protein kinase B and PI3K/AKT/mTOR pathway. Neil B. Ruderman combines subjects such as ULK1, Enzyme activator, Signal transduction, Adiponectin and RHEB with his study of AMP-activated protein kinase. His studies in Insulin resistance integrate themes in fields like Dyslipidemia, Protein kinase C, Diacylglycerol kinase and Type 2 diabetes.
Internal medicine, Endocrinology, AMPK, Insulin resistance and AMP-activated protein kinase are his primary areas of study. Internal medicine is represented through his Insulin and Skeletal muscle research. His research in AMPK intersects with topics in Adipose tissue and Sirtuin 1.
His Insulin resistance research is multidisciplinary, relying on both Dyslipidemia and Type 2 diabetes. His AMP-activated protein kinase study deals with Lipolysis intersecting with Adipocyte, Triglyceride lipase, Forskolin and Myocyte. His Protein kinase A research is multidisciplinary, incorporating elements of Protein deacetylase and Glucose uptake.
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Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α
Samar I. Itani;Neil B. Ruderman;Frank Schmieder;Guenther Boden.
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
Matthew D. Hirschey;Tadahiro Shimazu;Tadahiro Shimazu;Eric Goetzman;Enxuan Jing.
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation
Eva Tomas;Tsu-Shuen Tsao;Asish K. Saha;Heather E. Murrey.
Proceedings of the National Academy of Sciences of the United States of America (2002)
The metabolically obese, normal-weight individual revisited.
N Ruderman;D Chisholm;X Pi-Sunyer;S Schneider.
AMPK and SIRT1: a long-standing partnership?
Neil B. Ruderman;X. Julia Xu;Lauren E Nelson;Jose M. Cacicedo.
American Journal of Physiology-endocrinology and Metabolism (2010)
Malonyl-CoA, fuel sensing, and insulin resistance
Neil B. Ruderman;Asish K. Saha;Demetrios Vavvas;Lee A. Witters.
American Journal of Physiology-endocrinology and Metabolism (1999)
SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1 POSSIBLE ROLE IN AMP-ACTIVATED PROTEIN KINASE ACTIVATION
Fan Lan;Jose M. Cacicedo;Neil Ruderman;Yasuo Ido.
Journal of Biological Chemistry (2008)
AMPK, insulin resistance, and the metabolic syndrome.
Neil B. Ruderman;David Carling;Marc Prentki;José M. Cacicedo.
Journal of Clinical Investigation (2013)
Mice Lacking Adiponectin Show Decreased Hepatic Insulin Sensitivity and Reduced Responsiveness to Peroxisome Proliferator-activated Receptor γ Agonists
Andrea R. Nawrocki;Michael W. Rajala;Eva Tomas;Utpal B. Pajvani.
Journal of Biological Chemistry (2006)
Activation of phosphatidylinositol 3-kinase by insulin.
Neil B. Ruderman;Rosana Kapeller;Morris F. White;Lewis C. Cantley.
Proceedings of the National Academy of Sciences of the United States of America (1990)
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