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Gary D. Lopaschuk

Gary D. Lopaschuk

D-Index & Metrics

Medicine

D-Index
127
Citations
58784
World Ranking
2832
National Ranking
113

Research.com Recognitions

  • 2007 - Fellow of the Royal Society of Canada Academy of Science

Overview

Gary D. Lopaschuk is affiliated with the University of Alberta in Canada and has contributed extensively to research in the fields of medicine, biochemistry, genetics, and molecular biology. Their work primarily focuses on cardiology and cardiovascular medicine, physiology, molecular biology, endocrinology, diabetes, metabolism, and surgery.

The scientist's research interests are reflected in topics such as cardiovascular function and risk factors, adipose tissue and metabolism, diet and metabolism studies, mitochondrial function and pathology, metabolism, diabetes, and cancer, pancreatic function and diabetes, and diet, metabolism, and disease.

Frequent publication venues for Gary D. Lopaschuk include:

  • Cardiovascular Research
  • Circulation Research
  • JACC Basic to Translational Science
  • Metabolism
  • Basic Research in Cardiology

Among recent papers featuring Gary D. Lopaschuk as an author are:

  • Mechanisms of Cardiovascular Benefits of Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors, 2020, JACC Basic to Translational Science
  • Ketone metabolism in the failing heart, 2020, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Additional recent publications related to the field but authored by frequent collaborators include:

  • Ketones can become the major fuel source for the heart but do not increase cardiac efficiency, 2020, Cardiovascular Research
  • Metabolic, structural and biochemical changes in diabetes and the development of heart failure, 2022, Diabetologia
  • Myocardial Ketones Metabolism in Heart Failure, 2020, Journal of Cardiac Failure

Frequent co-authors who have collaborated extensively with Gary D. Lopaschuk include:

  • Qutuba G. Karwi
  • Cory S. Wagg
  • John R. Ussher
  • Kim L. Ho
  • Keshav Gopal

The scientist's contributions have been recognized by an award as a Fellow of the Royal Society of Canada in 2007, within the Academy of Science.

Best Publications

  • Myocardial Substrate Metabolism in the Normal and Failing Heart

    William C. Stanley;Fabio A. Recchia;Gary D. Lopaschuk

  • Myocardial Fatty Acid Metabolism in Health and Disease

    Gary D. Lopaschuk;John R. Ussher;Clifford D. L. Folmes;Jagdip S. Jaswal

  • Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

    Timothy R. Koves;John R. Ussher;Robert C. Noland;Dorothy Slentz

  • A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth

    Sébastien Bonnet;Stephen L. Archer;Joan Allalunis-Turner;Alois Haromy

  • The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus

    Brian N. Finck;John J. Lehman;Teresa C. Leone;Michael J. Welch

  • The Antianginal Drug Trimetazidine Shifts Cardiac Energy Metabolism From Fatty Acid Oxidation to Glucose Oxidation by Inhibiting Mitochondrial Long-Chain 3-Ketoacyl Coenzyme A Thiolase

    Paul F. Kantor;Arnaud Lucien;Raymond Kozak;Gary D. Lopaschuk

  • Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

    William C. Stanley;Gary D. Lopaschuk;Jennifer L. Hall;James G. McCormack

  • High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5′-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase

    Naomi Kudo;Amy J. Barr;Rick L. Barr;Snehal Desai

  • Cardiovascular remodelling in coronary artery disease and heart failure

    Gerd Heusch;Peter Libby;Bernard Gersh;Derek Yellon

  • Regulation of fatty acid oxidation in the mammalian heart in health and disease.

    G D Lopaschuk;D D Belke;J Gamble;T Itoi

  • Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts

    M. F. Allard;B. O. Schonekess;S. L. Henning;D. R. English

  • Regulation of energy substrate metabolism in the diabetic heart

    William C Stanley;Gary D Lopaschuk;James G McCormack

  • Mechanisms of Cardiovascular Benefits of Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: A State-of-the-Art Review

    Gary D. Lopaschuk;Subodh Verma

  • Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation

    Gary D Lopaschuk;Jagdip S Jaswal

  • Cardiac Energy Metabolism in Heart Failure

    Gary D. Lopaschuk;Qutuba G. Karwi;Rong Tian;Adam R. Wende

  • Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts.

    M. Saddik;G.D. Lopaschuk

  • Mitochondrial fatty acid oxidation alterations in heart failure, ischaemic heart disease and diabetic cardiomyopathy.

    N Fillmore;J Mori;G D Lopaschuk

  • Dichloroacetate, a Metabolic Modulator, Prevents and Reverses Chronic Hypoxic Pulmonary Hypertension in Rats Role of Increased Expression and Activity of Voltage-Gated Potassium Channels

    Evangelos D. Michelakis;M. Sean McMurtry;Xi Chen Wu;Jason R.B. Dyck

  • AMPK alterations in cardiac physiology and pathology: enemy or ally?

    Jason R. B. Dyck;Gary D. Lopaschuk

  • Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry.

    Toshiyuki Fukao;Gary D. Lopaschuk;Grant A. Mitchell

Frequent Co-Authors

Jason R.B. Dyck
Jason R.B. Dyck University of Alberta
Gavin Y. Oudit
Gavin Y. Oudit University of Alberta
Richard Schulz
Richard Schulz University of Alberta
Evangelos D. Michelakis
Evangelos D. Michelakis University of Alberta
Stephen L. Archer
Stephen L. Archer Queen's University
Daniel P. Kelly
Daniel P. Kelly University of Pennsylvania
George A. Brooks
George A. Brooks University of California, Berkeley
Deborah M. Muoio
Deborah M. Muoio Duke University
Mark Wilson
Mark Wilson University of California, Berkeley
Christine Des Rosiers
Christine Des Rosiers University of Montreal

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