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D-Index & Metrics

Medicine

D-Index
110
Citations
48872
World Ranking
5520
National Ranking
2977

Overview

George A. Brooks is affiliated with the University of California, Berkeley, United States. Their research spans several interconnected fields in biology and medicine, with a primary focus on metabolism and physiology. Their work contributes to a deeper understanding of metabolic processes involving lactate and its roles in various physiological contexts.

The scientist's recent publications include several notable papers such as:

  • Lactate as a fulcrum of metabolism (2020) published in Redox Biology
  • The anaerobic threshold: 50+ years of controversy (2020) published in The Journal of Physiology
  • Lactate as a myokine and exerkine: drivers and signals of physiology and metabolism (2023) published in Journal of Applied Physiology
  • Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells (2020) published in Frontiers in Oncology
  • The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU (2020) published in Journal of Sport and Health Science

The frequent co-authors collaborating with George A. Brooks include:

  • José A. Arevalo
  • Robert G. Leija
  • Adam D. Osmond
  • Justin J. Duong
  • Casey C. Curl

Brooks publishes regularly in various scientific journals, with the most recurrent venues being:

  • Medicine & Science in Sports & Exercise
  • The Journal of Physiology
  • American Journal of Physiology-Endocrinology and Metabolism
  • Physiology
  • The FASEB Journal

The main fields of study addressed in Brooks's research involve Medicine and Biochemistry, Genetics and Molecular Biology. Within these, subfields include Molecular Biology, Physiology, Cell Biology, Complementary and alternative medicine, and Cardiology and Cardiovascular Medicine.

Key topics in their research covers areas such as:

  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • Muscle metabolism and nutrition
  • Diet and metabolism studies
  • Cardiovascular and exercise physiology
  • Sports Performance and Training
  • Cancer, Hypoxia, and Metabolism

Best Publications

  • Exercise physiology: Human bioenergetics and its applications

    George A. Brooks

  • Free radicals and tissue damage produced by exercise

    Kelvin J.A. Davies;Alexandre T. Quintanilha;George A. Brooks;Lester Packer

  • Balance of carbohydrate and lipid utilization during exercise: the "crossover" concept

    George A. Brooks;Jacques Mercier

  • Anaerobic threshold: review of the concept and directions for future research

    George A. Brooks

  • The Science and Translation of Lactate Shuttle Theory

    George A. Brooks

  • Cell-cell and intracellular lactate shuttles

    George A. Brooks

  • Muscular efficiency during steady-rate exercise: effects of speed and work rate.

    Glenn A. Gaesser;George A. Brooks

  • Metabolic bases of excess post-exercise oxygen consumption: a review

    Glenn A. Gaesser;Glenn A. Gaesser;George A. Brooks;George A. Brooks

  • Endurance training affects lactate clearance, not lactate production

    Casey M. Donovan;George A. Brooks

  • The lactate shuttle during exercise and recovery.

    George A. Brooks

  • Chronically and acutely exercised rats: biomarkers of oxidative stress and endogenous antioxidants

    Jiankang Liu;Helen C. Yeo;Eva Övervik-Douki;Tory Hagen

  • Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle

    G A Brooks;H Dubouchaud;M Brown;J P Sicurello

  • Determination of metabolic and heart rate responses of rats to treadmill exercise.

    G. A. Brooks;T. P. White

  • Intra- and extra-cellular lactate shuttles.

    George A. Brooks

  • Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect

    Iñigo San-Millán;George A. Brooks

  • Biochemical adaptation of mitochondria, muscle, and whole-animal respiration to endurance training.

    Kelvin J.A. Davies;Kelvin J.A. Davies;Lester Packer;George A. Brooks

  • Lactate shuttles in Nature

    G. A. Brooks

  • Defining hypoxia: a systems view of VO2, glycolysis, energetics, and intracellular PO2.

    R. J. Connett;C. R. Honig;T. E. J. Gayeski;G. A. Brooks

  • Endurance training, expression, and physiology of LDH, MCT1, and MCT4 in human skeletal muscle

    Hervé Dubouchaud;Hervé Dubouchaud;Gail E. Butterfield;Eugene E. Wolfel;Bryan C. Bergman

  • Current concepts in lactate exchange.

    George A. Brooks

Frequent Co-Authors

John T. Reeves
John T. Reeves University of Colorado Anschutz Medical Campus
Lester Packer
Lester Packer University of Southern California
Gary D. Lopaschuk
Gary D. Lopaschuk University of Alberta
Kelvin J.A. Davies
Kelvin J.A. Davies University of Southern California
Lorna G. Moore
Lorna G. Moore University of Colorado Denver
Bruce N. Ames
Bruce N. Ames University of California, Berkeley
Wei Gao
Wei Gao California Institute of Technology
Dale A. Schoeller
Dale A. Schoeller University of Wisconsin–Madison
Ronald M. Krauss
Ronald M. Krauss University of California, San Francisco
Ali Javey
Ali Javey University of California, Berkeley

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