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Mark A. Tarnopolsky

Mark A. Tarnopolsky

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Medicine
Canada
2023

D-Index & Metrics

Medicine

D-Index
145
Citations
71307
World Ranking
1390
National Ranking
44

Research.com Recognitions

  • 2023 - Research.com Medicine in Canada Leader Award

Overview

Mark A. Tarnopolsky is affiliated with McMaster University in Canada and has an extensive body of research primarily situated at the intersection of medicine, biochemistry, genetics, and molecular biology. Their work encompasses a broad range of topics with a focus on mitochondrial function and pathology, neurogenetic and muscular disorders research, and metabolism and genetic disorders.

Their research spans several main fields including Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in subfields such as Molecular Biology, Physiology, Genetics, Cellular and Molecular Neuroscience, and Neurology.

Frequent topics in Tarnopolsky's publications include:

  • Mitochondrial Function and Pathology
  • Neurogenetic and Muscular Disorders Research
  • Adipose Tissue and Metabolism
  • Muscle Physiology and Disorders
  • Metabolism and Genetic Disorders
  • Genetic Neurodegenerative Diseases
  • Genomics and Rare Diseases

They have published multiple papers in notable venues, with the most frequent publication outlets being:

  • Nutrients
  • Genetics in Medicine
  • Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology

Among recent notable papers authored or coauthored by Tarnopolsky are:

  • "Extracellular Vesicles and Exosomes: Insights From Exercise Science," 2021, Frontiers in Physiology
  • "Safety and efficacy of avalglucosidase alfa versus alglucosidase alfa in patients with late-onset Pompe disease (COMET): a phase 3, randomised, multicentre trial," 2021, The Lancet Neurology
  • "Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis," 2021, Nature Medicine
  • "Safety and efficacy of cipaglucosidase alfa plus miglustat versus alglucosidase alfa plus placebo in late-onset Pompe disease (PROPEL): an international, randomised, double-blind, parallel-group, phase 3 trial," 2021, The Lancet Neurology
  • "Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance," 2022, Nature Communications

Collaborations have included frequent coauthors such as Lauren Brady, Joshua P. Nederveen, Mats I. Nilsson, Kym M. Boycott, and Bart P. Hettinga. These collaborators indicate a strong network in the fields related to genetics, neurology, and physiology.

Best Publications

  • Short‐term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance

    Martin J. Gibala;Jonathan P. Little;Martin Van Essen;Geoffrey P. Wilkin

  • Gender differences in strength and muscle fiber characteristics.

    A. E. J. Miller;J. D. MacDougall;Mark A. Tarnopolsky;Digby G. Sale

  • Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men

    Daniel R Moore;Meghann J Robinson;Jessica L Fry;Jason E Tang

  • Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men

    Jason E. Tang;Daniel R. Moore;Gregory W. Kujbida;Mark A. Tarnopolsky

  • A practical model of low‐volume high‐intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms

    Jonathan P. Little;Adeel Safdar;Geoffrey P. Wilkin;Mark A. Tarnopolsky

  • Protein Requirements for Endurance Athletes

    Mark Tarnopolsky

  • Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters

    Joseph W Hartman;Jason E Tang;Sarah B Wilkinson;Mark A Tarnopolsky

  • Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle

    Sarah B. Wilkinson;Stuart M. Phillips;Philip J. Atherton;Rekha Patel

  • Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes

    Jonathan Peter Little;Jenna B Gillen;Mike Percival;Adeel Safdar

  • American College of Sports Medicine roundtable. The physiological and health effects of oral creatine supplementation.

    R.L. Terjung;P. Clarkson;E.R. Eichner;P.L. Greenhaff

  • Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage

    Sarah B Wilkinson;Mark A Tarnopolsky;Maureen J MacDonald;Jay R MacDonald

  • Postactivation potentiation, fiber type, and twitch contraction time in human knee extensor muscles

    Taku Hamada;Digby G. Sale;J. Duncan MacDougall;Mark A. Tarnopolsky

  • Changes in human muscle protein synthesis after resistance exercise

    A. Chesley;J. D. MacDougall;M. A. Tarnopolsky;S. A. Atkinson

  • Gender differences in substrate for endurance exercise

    L. J. Tarnopolsky;J. D. MacDougall;S. A. Atkinson;M. A. Tarnopolsky

  • Evaluation of protein requirements for trained strength athletes

    M. A. Tarnopolsky;S. A. Atkinson;J. D. MacDougall;A. Chesley

  • Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men.

    Yifan Yang;Leigh Breen;Nicholas A. Burd;Amy J. Hector

  • Diagnosis and management of mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society

    Sumit Parikh;Amy Goldstein;Mary Kay Koenig;Fernando Scaglia

  • Protein requirements and muscle mass/strength changes during intensive training in novice bodybuilders

    P. W. Lemon;M. A. Tarnopolsky;J. D. MacDougall;S. A. Atkinson

  • Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise

    D. J. Mahoney;G. Parise;S. Melov;A. Safdar

  • Low-volume interval training improves muscle oxidative capacity in sedentary adults.

    Melanie S. Hood;Jonathan P. Little;Mark A. Tarnopolsky;Frank Myslik

Frequent Co-Authors

Stuart M. Phillips
Stuart M. Phillips McMaster University
Simon Melov
Simon Melov Buck Institute for Research on Aging
Gregory R. Steinberg
Gregory R. Steinberg McMaster University
Guy A. Rouleau
Guy A. Rouleau Montreal Neurological Institute and Hospital
Kym M. Boycott
Kym M. Boycott Children's Hospital of Eastern Ontario
Tomas A. Prolla
Tomas A. Prolla University of Wisconsin–Madison
Brian H. Robinson
Brian H. Robinson Hospital for Sick Children
Ziv Gan-Or
Ziv Gan-Or McGill University
Eric P. Hoffman
Eric P. Hoffman Binghamton University
Jacek Majewski
Jacek Majewski McGill University

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