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Mark A. Febbraio

Mark A. Febbraio

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Medicine
Australia
2023

D-Index & Metrics

Medicine

D-Index
129
Citations
55629
World Ranking
2621
National Ranking
72

Research.com Recognitions

  • 2023 - Research.com Medicine in Australia Leader Award

Overview

Mark A. Febbraio is affiliated with Monash University in Australia and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Physiology, Epidemiology, Immunology, and Surgery.

The primary research topics that Mark A. Febbraio has focused on include:

  • Adipose Tissue and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Adipokines, Inflammation, and Metabolic Diseases
  • Metabolism, Diabetes, and Cancer
  • Diet, Metabolism, and Disease
  • Exercise and Physiological Responses
  • Immune Cell Function and Interaction

Frequent co-authors collaborating with Mark A. Febbraio are:

  • Darren C. Henstridge
  • John W. Scott
  • Casey L. Egan
  • Peter J. Meikle
  • Oliver K Fuller

The scientist has published regularly in notable journals, with the most frequent venues including:

  • Science Advances
  • Nature Reviews Endocrinology
  • Nature Metabolism
  • Nature
  • iScience

Recent notable publications by Mark A. Febbraio include:

  • "Exerkines in health, resilience and disease" (2022, Nature Reviews Endocrinology)
  • "Embracing cancer complexity: Hallmarks of systemic disease" (2024, Cell)
  • "Fructose stimulated de novo lipogenesis is promoted by inflammation" (2020, Nature Metabolism)
  • "Sex-specific adipose tissue imprinting of regulatory T cells" (2020, Nature)
  • "Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary" (2022, Science Advances)

Their collective research encompasses multiple intersecting areas of metabolic health, inflammation, immune regulation, and physiological responses to environmental and dietary factors.

Best Publications

  • Muscles, exercise and obesity: skeletal muscle as a secretory organ

    Bente Klarlund Pedersen;Mark A. Febbraio

  • Muscle as an endocrine organ: focus on muscle-derived interleukin-6.

    Bente K. Pedersen;Mark A. Febbraio

  • Muscle-derived interleukin-6: mechanisms for activation and possible biological roles

    Mark A. Febbraio;Bente Klarlund Pedersen

  • Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase

    Andrew L Carey;Gregory R Steinberg;S Lance Macaulay;Walter G Thomas

  • Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans.

    Rebecca Starkie;Sisse Rye Ostrowski;Sune Jauffred;Mark Febbraio

  • Interleukin-6 stimulates lipolysis and fat oxidation in humans.

    Gerrit van Hall;Adam Steensberg;Massimo Sacchetti;Christian Fischer

  • Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase

    Vance B Matthews;M-B Astrom;M H S Chan;Clinton R Bruce

  • Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

    Jan Mauer;Bhagirath Chaurasia;Julia Goldau;Merly C Vogt

  • Searching for the exercise factor: is IL-6 a candidate?

    B.K. Pedersen;A. Steensberg;C. Fischer;C. Keller

  • Exosome-dependent Trafficking of HSP70 A NOVEL SECRETORY PATHWAY FOR CELLULAR STRESS PROTEINS

    Graeme I. Lancaster;Mark A. Febbraio

  • Reactive oxygen species enhance insulin sensitivity.

    Kim Yong Loh;Haiyang Deng;Atsushi Fukushima;Xiaochu Cai

  • HSP72 protects against obesity-induced insulin resistance.

    Jason Chung;Anh-Khoi Nguyen;Darren C Colin Henstridge;Anna G Holmes

  • IL-6 and TNF-α expression in, and release from, contracting human skeletal muscle

    Adam Steensberg;Charlotte Keller;Rebecca L. Starkie;Takuya Osada

  • Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

    Andrea L Hevener;Jerrold M Olefsky;Donna Reichart;MT Audrey Nguyen

  • Contraction-induced myokine production and release: is skeletal muscle an endocrine organ?

    Mark A. Febbraio;Bente K. Pedersen

  • Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content

    Adam Steensberg;Mark A. Febbraio;Mark A. Febbraio;Takuya Osada;Peter Schjerling

  • Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

    Gregory r Steinberg;Belinda J Michell;Bryce J W Jw van Denderen;Matthew James Watt

  • Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise

    Martin Whitham;Martin Whitham;Benjamin L. Parker;Martin Friedrichsen;Janne R. Hingst

  • Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction

    Mark A. Febbraio;Natalie Hiscock;Natalie Hiscock;Massimo Sacchetti;Christian P. Fischer

  • High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus

    Brian G. Drew;Stephen J. Duffy;Melissa F. Formosa;Alaina K. Natoli

Frequent Co-Authors

Matthew J. Watt
Matthew J. Watt University of Melbourne
Bente Klarlund Pedersen
Bente Klarlund Pedersen University of Copenhagen
Mark Hargreaves
Mark Hargreaves University of Melbourne
Bruce E. Kemp
Bruce E. Kemp Australian Catholic University
Bronwyn A. Kingwell
Bronwyn A. Kingwell Baker IDI Heart and Diabetes Institute
Peter J. Meikle
Peter J. Meikle Baker IDI Heart and Diabetes Institute
Gregory R. Steinberg
Gregory R. Steinberg McMaster University
John A. Hawley
John A. Hawley Australian Catholic University
Axel Kallies
Axel Kallies University of Melbourne
Michael Carey
Michael Carey University of California, Los Angeles

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