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Biology and Biochemistry

D-Index
75
Citations
19382
World Ranking
5338
National Ranking
2529

Overview

Donald L. Gill is affiliated with Pennsylvania State University in the United States. Their research intersects multiple disciplines within life sciences, predominantly focusing on Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine.

The scientist's work is notably concentrated in the fields of Sensory Systems, Cellular and Molecular Neuroscience, Molecular Biology, Biochemistry, and Physiology. Key research topics include Ion Channels and Receptors, Neurobiology and Insect Physiology Research, Phytochemicals and Antioxidant Activities, Ion Channel Regulation and Function, Photoreceptor and Optogenetics Research, ATP Synthase and ATPases Research, and Mitochondrial Function and Pathology.

Recent significant publications from Donald L. Gill examine diverse aspects of calcium signaling and ion channel functionality. These papers include:

  • The native ORAI channel trio underlies the diversity of Ca2+ signaling events, 2020, Nature Communications
  • Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels, 2020, Cell Calcium
  • Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling, 2021, Cell Reports
  • Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis, 2020, eLife
  • Engineering of NEMO as calcium indicators with large dynamics and high sensitivity, 2023, Nature Methods

Donald L. Gill frequently collaborates with several other researchers, including Yandong Zhou, Youjun Wang, Mohamed Trebak, James H. Baraniak, and Ryan E. Yoast. These collaborations have contributed to a body of work published in various scientific venues.

The scientist's work regularly appears in journals and repositories such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cell Calcium, Biophysical Journal, and Cell Reports, demonstrating a consistent presence in both preprint and peer-reviewed literature.

Best Publications

  • STIM proteins: dynamic calcium signal transducers

    Jonathan Soboloff;Brad S. Rothberg;Muniswamy Madesh;Donald L. Gill

  • Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels.

    Hong-Tao Ma;Randen L. Patterson;Damian B. van;Rossum

  • Orai1 and STIM reconstitute store-operated calcium channel function.

    Jonathan Soboloff;Maria A. Spassova;Xiang D. Tang;Thamara Hewavitharana

  • CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel

    Monika Vig;Andreas Beck;James M. Billingsley;Annette Lis

  • Dynamic Assembly of TRPC1-STIM1-Orai1 Ternary Complex Is Involved in Store-operated Calcium Influx EVIDENCE FOR SIMILARITIES IN STORE-OPERATED AND CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL COMPONENTS

    Hwei Ling Ong;Kwong Tai Cheng;Xibao Liu;Bidhan C. Bandyopadhyay

  • A common mechanism underlies stretch activation and receptor activation of TRPC6 channels

    Maria A. Spassova;Thamara Hewavitharana;Wen Xu;Jonathan Soboloff

  • Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin

    Tarun K. Ghosh;Peggy S. Eis;Julienne M. Mullaney;Cynthia L. Ebert

  • Store-operated Ca2+ entry: evidence for a secretion-like coupling model.

    Randen L Patterson;Damian B van Rossum;Donald L Gill

  • The cellular and molecular basis of store-operated calcium entry

    Kartik Venkatachalam;Damian B. van Rossum;Randen L. Patterson;Hong Tao Ma

  • Intracellular Calcium Release Mediated by Sphingosine Derivatives Generated in Cells

    Tarun K. Ghosh;Junhui Bian;Donald L. Gill

  • Regulation of Canonical Transient Receptor Potential (TRPC) Channel Function by Diacylglycerol and Protein Kinase C

    Kartik Venkatachalam;Fei Zheng;Donald L. Gill

  • The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin.

    Yuzo Furuya;Per Lundmo;Per Lundmo;Alison D. Short;Donald L. Gill

  • The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and CaV1.2 Channels

    Youjun Wang;Xiaoxiang Deng;Salvatore Mancarella;Eunan Hendron

  • STIM1 has a plasma membrane role in the activation of store-operated Ca2+ channels

    Maria A. Spassova;Jonathan Soboloff;Li Ping He;Wen Xu

  • Intracellular Ca2+ pool content is linked to control of cell growth

    Alison D. Short;Junhui Bian;Tarun K. Ghosh;Richard T. Waldron

  • Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform

    X.-Z. Shawn Xu;Fabian Moebius;Donald L. Gill;Craig Montell

  • STIM2 Is an Inhibitor of STIM1-Mediated Store-Operated Ca2+ Entry

    Jonathan Soboloff;Maria A. Spassova;Thamara Hewavitharana;Li Ping He

  • Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium.

    Tarun K. Ghosh;Junhui Bian;Donald L. Gill

  • Calcium transport mechanisms in membrane vesicles from guinea pig brain synaptosomes.

    D L Gill;E F Grollman;L D Kohn

  • The Short N-terminal Domains of STIM1 and STIM2 Control the Activation Kinetics of Orai1 Channels

    Yandong Zhou;Salvatore Mancarella;Youjun Wang;Chanyu Yue

Frequent Co-Authors

Mohamed Trebak
Mohamed Trebak Pennsylvania State University
Muniswamy Madesh
Muniswamy Madesh The University of Texas at Austin
Tomohiro Kurosaki
Tomohiro Kurosaki Osaka University
Steven R. Houser
Steven R. Houser Temple University
Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University
Indu S. Ambudkar
Indu S. Ambudkar National Institutes of Health
Israel Sekler
Israel Sekler Ben-Gurion University of the Negev
David I. Yule
David I. Yule University of Rochester
Craig Montell
Craig Montell University of California, Santa Barbara
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine

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