What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Biophysics, Biochemistry, Cell biology, ORAI1 and STIM1.
His studies in Biophysics integrate themes in fields like TRPC Cation Channels, Molecular biology, Thapsigargin, Ion channel and Patch clamp.
His Biochemistry study frequently links to related topics such as Voltage-dependent calcium channel.
The Cell biology study combines topics in areas such as HEK 293 cells and Transient receptor potential channel, TRPC.
His Transient receptor potential channel study combines topics from a wide range of disciplines, such as Signal transduction and Phospholipase C.
His research integrates issues of Protein structure and C-terminus in his study of ORAI1.
His most cited work include:
- Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. (341 citations)
- A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels (268 citations)
- Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels. (262 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Biophysics, Cell biology, Biochemistry, TRPC3 and TRPC.
Klaus Groschner has researched Biophysics in several fields, including Extracellular, STIM1, ORAI1 and Intracellular.
His Cell biology research focuses on HEK 293 cells and how it relates to Endogeny.
His study in Biochemistry is interdisciplinary in nature, drawing from both Förster resonance energy transfer, Nitric oxide and Voltage-dependent calcium channel.
His research investigates the connection with TRPC3 and areas like Ion channel which intersect with concerns in Lipid signaling.
His TRPC study integrates concerns from other disciplines, such as TRPC1 and Cell signaling.
He most often published in these fields:
- Biophysics (35.64%)
- Cell biology (35.64%)
- Biochemistry (27.23%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (35.64%)
- TRPC (25.25%)
- TRPC3 (25.25%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, TRPC, TRPC3, Transient receptor potential channel and Biophysics.
His Cell biology study incorporates themes from HEK 293 cells, Cell and NFAT.
His TRPC research incorporates elements of Lipid metabolism, Calcium and Cellular functions.
TRPC3 is a subfield of Biochemistry that Klaus Groschner explores.
His Transient receptor potential channel research includes themes of Neuroscience and Gene isoform.
His studies deal with areas such as Extracellular, Endoplasmic reticulum and Intracellular as well as Biophysics.
Between 2013 and 2021, his most popular works were:
- Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line (65 citations)
- Cholesterol modulates Orai1 channel function (58 citations)
- Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo. (52 citations)
In his most recent research, the most cited papers focused on:
Cell biology, Ion channel, Gating, TRPC3 and Biophysics are his primary areas of study.
Klaus Groschner has included themes like Endocrinology, Internal medicine, Calcium, Angiotensin II and Patch clamp in his Cell biology study.
In his work, Transient receptor potential channel, TRPC, Molecule and Cell is strongly intertwined with Lipid signaling, which is a subfield of Ion channel.
His Gating research includes elements of STIM1, ORAI1 and Transmembrane domain.
His Transmembrane domain research entails a greater understanding of Biochemistry.
His research integrates issues of Diacylglycerol kinase, Endoplasmic reticulum, Intracellular, Förster resonance energy transfer and In vivo in his study of Biophysics.
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