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D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
14747
World Ranking
9662
National Ranking
84

Overview

Ernst Malle is affiliated with the Medical University of Graz in Austria. Their research spans a variety of topics within the intersecting fields of biochemistry, genetics, molecular biology, and medicine. The primary areas of study include molecular biology, immunology, neurology, physiology, as well as nutrition and dietetics.

The scientist's published work demonstrates a focus on mechanisms related to oxidative processes and inflammation. Main research topics addressed in the publications include neutrophil function, myeloperoxidase activity, oxidative mechanisms, nitric oxide and endothelin effects, neuroinflammation and neurodegeneration processes, mitochondrial function and pathology, heme oxygenase-1 and carbon monoxide biology, sphingolipid metabolism and signaling, and the study of vitamin C along with antioxidants.

Frequent publication venues for Ernst Malle's research comprise:

  • Antioxidants
  • Free Radical Biology and Medicine
  • International Journal of Molecular Sciences
  • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  • Pharmacological Research

Collaborations feature coauthors such as Corina T. Madreiter-Sokolowski, Chintan N. Koyani, Wolfgang Sattler, Michael J. Davies, and Eva Bernhart, indicating a network engaged extensively in similar research domains.

Recent papers authored or coauthored by Ernst Malle include:

  • "Empagliflozin protects heart from inflammation and energy depletion via AMPK activation," 2020, Pharmacological Research
  • "MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia," 2020, Journal of Neuroinflammation
  • "Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity," 2020, Nature Immunology
  • "Halogenation Activity of Mammalian Heme Peroxidases," 2022, Antioxidants
  • "Targeting organ-specific mitochondrial dysfunction to improve biological aging," 2024, Pharmacology & Therapeutics

Best Publications

  • The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

    Liliana Schaefer;Andrea Babelova;Eva Kiss;Heinz J. Hausser

  • Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

    Linda J. Hazell;Leslie Arnold;Dimity Flowers;Georg Waeg

  • Myeloperoxidase: a target for new drug development?

    E Malle;P G Furtmüller;W Sattler;C Obinger

  • Human serum amyloid A (SAA) protein: a prominent acute-phase reactant for clinical practice.

    E. Malle;F. C. De Beer

  • Myeloperoxidase in kidney disease

    Ernst Malle;Thomas Buch;Thomas Buch;Hermann Josef Grone;Hermann Josef Grone

  • Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions. Colocalization of myeloperoxidase and hypochlorite-modified proteins

    Ernst Malle;Georg Waeg;Renate Schreiber;Elisabeth F. Gröne

  • Serum amyloid A: An acute-phase protein involved in tumour pathogenesis

    E. Malle;S. Sodin-Semrl;A. Kovacevic

  • Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis.

    Sander S. Rensen;Yanti Slaats;Jeroen Nijhuis;Anneke Jans

  • Serum amyloid A (SAA): an acute phase protein and apolipoprotein.

    Ernst Malle;Armin Steinmetz;John G. Raynes

  • Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model.

    Zoltan Balazs;Ute Panzenboeck;Astrid Hammer;Andrea Sovic

  • Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity.

    Cathleen Cover;Jie Liu;Anwar Farhood;Ernst Malle

  • Generation of hypochlorite-modified proteins by neutrophils during ischemia-reperfusion injury in rat liver: attenuation by ischemic preconditioning.

    Tadashi Hasegawa;Ernst Malle;Anwar Farhood;Hartmut Jaeschke

  • Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid.

    Ernst Malle;Gunther Marsche;Jürgen Arnhold;Michael J. Davies

  • ABCA1 and Scavenger Receptor Class B, Type I, Are Modulators of Reverse Sterol Transport at an in Vitro Blood-Brain Barrier Constituted of Porcine Brain Capillary Endothelial Cells

    Ute Panzenboeck;Zoltan Balazs;Andrea Sovic;Andelko Hrzenjak

  • Oxidant stress in hyperlipidemia-induced renal damage.

    Hartmut Scheuer;Wilfried Gwinner;Jan Hohbach;Elisabeth F. Gröne

  • Immunologic Detection and Measurement of Hypochlorite-Modified LDL With Specific Monoclonal Antibodies

    Ernst Malle;Linda Hazell;Roland Stocker;Wolfgang Sattler

  • Immunological evidence for hypochlorite-modified proteins in human kidney.

    Ernst Malle;Christian Woenckhaus;Georg Waeg;Hermann Esterbauer

  • Hypochlorite-modified High Density Lipoprotein, a High Affinity Ligand to Scavenger Receptor Class B, Type I, Impairs High Density Lipoprotein-dependent Selective Lipid Uptake and Reverse Cholesterol Transport

    Gunther Marsche;Astrid Hammer;Olga Oskolkova;Karen F. Kozarsky

  • Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E.

    Daniel Goti;Andelko Hrzenjak;Sanja Levak-Frank;Sasa Frank

  • Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line

    Chouyang Li;Simin Rezania;Sarah Kammerer;Armin Andreas Sokolowski

Frequent Co-Authors

Wolfgang Sattler
Wolfgang Sattler Medical University of Graz
Michael J. Davies
Michael J. Davies University of Copenhagen
Gert M. Kostner
Gert M. Kostner University of Graz
John M. Whitelock
John M. Whitelock University of New South Wales
Hermann Josef Gröne
Hermann Josef Gröne German Cancer Research Center
Winfried März
Winfried März Medical University of Graz
Paul G. Furtmüller
Paul G. Furtmüller BOKU University
Christian Obinger
Christian Obinger BOKU University
Wolfgang F. Graier
Wolfgang F. Graier Medical University of Graz
Marcus E. Kleber
Marcus E. Kleber Heidelberg University

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