What is he best known for?
The fields of study he is best known for:
- Enzyme
- Biochemistry
- Internal medicine
His main research concerns Myeloperoxidase, Hypochlorous acid, Biochemistry, Hydrogen peroxide and Enzyme.
His Myeloperoxidase study integrates concerns from other disciplines, such as NADPH oxidase, Superoxide dismutase, Phagosome, Microbiology and Superoxide.
The concepts of his Hypochlorous acid study are interwoven with issues in Peroxidase, Inflammation, Neutrophil extracellular traps and Biomarker.
Anthony J. Kettle focuses mostly in the field of Biochemistry, narrowing it down to topics relating to Chloramine and, in certain cases, Hypobromous acid.
His Hydrogen peroxide research is multidisciplinary, relying on both Radical and Oxygen.
His Enzyme course of study focuses on Hydrazide and Zymosan, Benzoic acid, Medicinal chemistry, Ferrous and Glutathione.
His most cited work include:
- Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing (1333 citations)
- Myeloperoxidase: a key regulator of neutrophil oxidant production (511 citations)
- Modeling the Reactions of Superoxide and Myeloperoxidase in the Neutrophil Phagosome: IMPLICATIONS FOR MICROBIAL KILLING* (428 citations)
What are the main themes of his work throughout his whole career to date?
Myeloperoxidase, Biochemistry, Hypochlorous acid, Hydrogen peroxide and Superoxide are his primary areas of study.
Anthony J. Kettle combines subjects such as Peroxidase, Enzyme and Oxidative stress with his study of Myeloperoxidase.
His Enzyme research is multidisciplinary, incorporating elements of Stereochemistry and Mechanism of action.
His studies deal with areas such as Phagosome, Chloramine and Microbiology as well as Hypochlorous acid.
His Hydrogen peroxide research is multidisciplinary, incorporating perspectives in Medicinal chemistry, Oxidative phosphorylation, Ferric, Hypothiocyanite and Redox.
His work focuses on many connections between Superoxide and other disciplines, such as Photochemistry, that overlap with his field of interest in Chloride.
He most often published in these fields:
- Myeloperoxidase (64.80%)
- Biochemistry (51.96%)
- Hypochlorous acid (41.34%)
What were the highlights of his more recent work (between 2016-2021)?
- Myeloperoxidase (64.80%)
- Hypochlorous acid (41.34%)
- Biochemistry (51.96%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Myeloperoxidase, Hypochlorous acid, Biochemistry, Hydrogen peroxide and Hypobromous acid.
Anthony J. Kettle has researched Myeloperoxidase in several fields, including Oxidative stress, Glutathione and Pharmacology.
Anthony J. Kettle interconnects Phagosome, Chloramine, Chlorine and Microbiology in the investigation of issues within Hypochlorous acid.
His work on Superoxide, Cysteine, Oxidative phosphorylation and Superoxide dismutase as part of general Biochemistry research is frequently linked to Ribonucleotide reductase, bridging the gap between disciplines.
His work carried out in the field of Hydrogen peroxide brings together such families of science as Peroxynitrite, Tyrosine, Photochemistry, Reactivity and Combinatorial chemistry.
His study looks at the relationship between Hypobromous acid and topics such as Peroxidase, which overlap with Sulfilimine.
Between 2016 and 2021, his most popular works were:
- Inhibition of MPO (Myeloperoxidase) Attenuates Endothelial Dysfunction in Mouse Models of Vascular Inflammation and Atherosclerosis. (27 citations)
- Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency. (26 citations)
- Intestinal helminth infection promotes IL-5- and CD4 + T cell-dependent immunity in the lung against migrating parasites (19 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Biochemistry
- Internal medicine
His primary areas of study are Myeloperoxidase, Hypochlorous acid, Hydrogen peroxide, Immunology and Glutathione.
In his works, he undertakes multidisciplinary study on Myeloperoxidase and Soluble guanylyl cyclase.
His Hypochlorous acid study is concerned with Biochemistry in general.
His studies in Hydrogen peroxide integrate themes in fields like Hydrogen peroxide metabolism, Oxidation reduction, Combinatorial chemistry and Metabolism.
His Immunology study also includes
- Bronchoalveolar lavage which intersects with area such as Uric acid, Allantoin, Pseudomonas aeruginosa, Urine and Urinary system,
- Cystic fibrosis that intertwine with fields like Oxidative stress, Antioxidant and Peroxidase.
His research in Phagosome intersects with topics in NADPH oxidase and Superoxide.
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