World's Best Scientists 2026 revealed!
Jamel El-Benna

Jamel El-Benna

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
11498
World Ranking
15006
National Ranking
588

Overview

Jamel El-Benna is affiliated with Inserm in France and has a significant body of research primarily focused on immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. Their work spans several key subfields, including immunology, molecular biology, genetics, pulmonary and respiratory medicine, and physiology.

El-Benna's research emphasizes various main topics such as neutrophil function, myeloperoxidase activity, oxidative mechanisms, immune cells involved in cancer, immune response and inflammation, neuroinflammation and neurodegeneration mechanisms, phagocytosis and immune regulation, nitric oxide and endothelin effects, and inflammasome-related immune disorders.

Among recent publications, the following papers are notable for their contributions to understanding immune mechanisms and oxidative stress:

  • Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis, 2022, Hepatology
  • The Dual Role of Reactive Oxygen Species-Generating Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Gastrointestinal Inflammation and Therapeutic Perspectives, 2020, Antioxidants and Redox Signaling
  • Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis, 2021, Cell Host & Microbe
  • Metformin Inhibits ROS Production by Human M2 Macrophages via the Activation of AMPK, 2022, Biomedicines
  • CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival, 2022, Gut

Frequent co-authors collaborating with El-Benna include:

  • Pham My-Chan Dang
  • Margarita Hurtado-Nedelec
  • Coralie Pintard
  • Samia Bedouhène
  • Ahmed Kouki

Their research is often published in venues specialized in immunopharmacology, blood-related studies, and biomedicine, including:

  • Inflammopharmacology
  • Blood
  • Biomedicines
  • Free Radical Biology and Medicine
  • Biochemical Pharmacology

El-Benna's work contributes to ongoing research into how oxidative stress and immune cell function influence inflammation, disease progression, and immune regulation in conditions such as fibrosis, cancer, and infectious diseases. The combination of molecular biology techniques and clinical insights situates their research at the intersection of basic science and therapeutic potential.

Best Publications

  • Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation.

    Alexandre Fontayne;Pham My-Chan Dang;Marie-Anne Gougerot-Pocidalo;Jamel El-Benna

  • Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane

    Jamel El-Benna;Jamel El-Benna;Pham My-Chan Dang;Pham My-Chan Dang;Marie-Anne Gougerot-Pocidalo;Marie-Anne Gougerot-Pocidalo

  • Priming of the neutrophil respiratory burst: role in host defense and inflammation.

    Jamel El-Benna;Jamel El-Benna;Margarita Hurtado-Nedelec;Margarita Hurtado-Nedelec;Viviana Marzaioli;Viviana Marzaioli;Jean-Claude Marie;Jean-Claude Marie

  • A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites

    Pham My-Chan Dang;Allan Stensballe;Tarek Boussetta;Houssam Raad

  • Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats.

    Sophie Lanone;Sébastien Bloc;Roberta Foresti;Abdelhamid Almolki

  • European contribution to the study of ROS : a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

    Javier Egea;Isabel Fabregat;Yves M Frapart;Pietro Ghezzi

  • Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes

    Carolina Jancic;Ariel Savina;Christina Wasmeier;Tanya Tolmachova

  • Mitochondrial Respiratory Chain and NAD(P)H Oxidase Are Targets for the Antiproliferative Effect of Carbon Monoxide in Human Airway Smooth Muscle

    Camille Taillé;Jamel El-Benna;Sophie Lanone;Jorge Boczkowski

  • Macrophage autophagy protects against liver fibrosis in mice

    Jasper Lodder;Timothé Denaës;Marie-Noële Chobert;JingHong Wan

  • The Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 1/2 Pathway Is Involved in formyl-Methionyl-Leucyl-Phenylalanine-Induced p47phox Phosphorylation in Human Neutrophils

    Cédric Dewas;Michèle Fay;Marie-Anne Gougerot-Pocidalo;Jamel El-Benna

  • Phagocyte NADPH oxidase: a multicomponent enzyme essential for host defenses.

    Jamel El-Benna;Pham My-Chan Dang;Marie-Anne Gougerot-Pocidalo;Carole Elbim

  • Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91phox/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67phox, and p47phox

    Houssam Raad;Marie-Hélène Paclet;Tarek Boussetta;Yolande Kroviarski

  • NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits

    Sahra A. Belambri;Loïc Rolas;Houssam Raad;Margarita Hurtado-Nedelec

  • Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

    Tonia Akoumianaki;Irene Kyrmizi;Isabel Valsecchi;Mark S. Gresnigt;Mark S. Gresnigt

  • TNF-α Induces Phosphorylation of p47phox in Human Neutrophils: Partial Phosphorylation of p47phox Is a Common Event of Priming of Human Neutrophils by TNF-α and Granulocyte-Macrophage Colony-Stimulating Factor

    Cédric Dewas;Pham My-Chan Dang;Marie-Anne Gougerot-Pocidalo;Jamel El-Benna

  • Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability.

    Camille Taillé;Jamel El-Benna;Sophie Lanone;My-Chan Dang

  • A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

    Vivien Béziat;Vivien Béziat;Juan Li;Jian-Xin Lin;Cindy S. Ma;Cindy S. Ma

  • Antioxidant effect of hydroxytyrosol, a polyphenol from olive oil: scavenging of hydrogen peroxide but not superoxide anion produced by human neutrophils.

    Yvonne O'Dowd;Fathi Driss;Pham My-Chan Dang;Carole Elbim

  • Punicic Acid a Conjugated Linolenic Acid Inhibits TNFα-Induced Neutrophil Hyperactivation and Protects from Experimental Colon Inflammation in Rats

    Tarek Boussetta;Houssam Raad;Philippe Lettéron;Marie-Anne Gougerot-Pocidalo

  • Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia.

    Li Qian;Sung-Jen Wei;Dan Zhang;Xiaoming Hu

Frequent Co-Authors

Philippe Lettéron
Philippe Lettéron Université Paris Cité
Jean-Paul Latgé
Jean-Paul Latgé University of Crete
Karim Hosni
Karim Hosni INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Mihai G. Netea
Mihai G. Netea Radboud University
Ulla G. Knaus
Ulla G. Knaus University College Dublin
Georgios Chamilos
Georgios Chamilos University of Crete
Carole Elbim
Carole Elbim Sorbonne University
Eun-Kyeong Jo
Eun-Kyeong Jo Chungnam National University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring online degree programs can expand your options in the biology and biochemistry fields, leading to diverse career paths. One fast-growing opportunity is in diagnostic imaging—online sonography programs allow students to prepare for careers as ultrasound technicians, with flexible schedules that suit working professionals or parents.

Similarly, online rad tech programs are ideal for those interested in becoming radiologic technologists, providing the essential technical and patient care skills needed in medical imaging.

For those drawn to nutrition, the best dietitian programs offer online master's degrees for aspiring dietitians and nutritionists, opening doors to roles in healthcare, research, and wellness industries.

If direct patient support appeals to you, many schools now offer online medical assisting school options, including financial aid, enabling students to fast-track into entry-level healthcare positions.

Choosing the right online degree not only broadens your knowledge base but also increases career flexibility in the evolving healthcare and life sciences sectors.

Best Scientists Citing Jamel El-Benna

Trending Scientists