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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
14423
World Ranking
10746
National Ranking
4668

Overview

Belinda Wilson is affiliated with the National Institutes of Health in the United States and specializes in research related to neuroscience and medicine. Their work primarily focuses on the mechanisms of neuroinflammation and neurodegeneration, with a notable emphasis on neurological diseases such as Parkinson's and Alzheimer's disease. The research also explores molecular and cellular neuroscience, physiology, and biological psychiatry.

The scientist's recent publications illustrate a focus on inflammation-related neuronal injury and degeneration processes. Notable papers include:

  • A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration (2020), Journal of Neuroinflammation
  • Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration (2020), Brain Behavior and Immunity
  • Loss of Brain Norepinephrine Elicits Neuroinflammation-Mediated Oxidative Injury and Selective Caudo-Rostral Neurodegeneration (2024), UNC Libraries
  • Dysfunction of the noradrenergic system drives inflammation, α-synucleinopathy, and neuronal loss in mouse colon (2023), Frontiers in Immunology
  • α-Synuclein, a chemoattractant, directs microglial migration via H 2 O 2 -dependent Lyn phosphorylation (2020), UNC Libraries

The main topics covered in Belinda Wilson's research include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological Disease Mechanisms and Treatments
  • Tryptophan and Brain Disorders
  • Stress Responses and Cortisol
  • Alzheimer's Disease Research and Treatments
  • Neuropeptides and Animal Physiology

Belinda Wilson collaborates frequently with a group of researchers, indicating a sustained partnership network. Frequent coauthors include Jau-Shyong Hong, Sheng Song, Qian Li, Xiaoming Hu, and Dan Zhang. These collaborations have contributed to the depth and breadth of their work in neuroinflammation and neurodegeneration.

The scientist has published extensively in several venues, with the most frequent publication outlets being UNC Libraries, Journal of Neuroinflammation, Brain Behavior and Immunity, and Frontiers in Immunology. UNC Libraries stands out with 12 publications, reflecting a strong repository of their research outputs.

Belinda Wilson's scholarly output spans various subfields such as neurology, physiology, molecular biology, cellular and molecular neuroscience, and biological psychiatry. The interplay of these disciplines reflects the integrated nature of their research on brain disorders.

Best Publications

  • Aggregated α-synuclein activates microglia: a process leading to disease progression in Parkinson’s disease

    Wei Zhang;Tongguang Wang;Zhong Pei;David S. Miller

  • Regional Difference in Susceptibility to Lipopolysaccharide-Induced Neurotoxicity in the Rat Brain: Role of Microglia

    Won-Gon Kim;Robert P. Mohney;Belinda Wilson;Gwang-Ho Jeohn

  • Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease

    Hui-Ming Gao;Janwei Jiang;Belinda Wilson;Wanqin Zhang

  • NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

    Liya Qin;Yuxin Liu;Tongguang Wang;Sung Jen Wei

  • HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

    Hui-Ming Gao;Hui Zhou;Feng Zhang;Belinda C. Wilson

  • Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase

    M. L. Block;X. Wu;X. Wu;Z. Pei;G. Li

  • Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes

    Po-See Chen;G. S. Peng;G. S. Peng;G. Li;S. Yang

  • Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.

    Hui-Ming Gao;Feng Zhang;Hui Zhou;Wayneho Kam

  • Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

    Xuefei Wu;Po See Chen;Po See Chen;Shannon Dallas;Belinda Wilson

  • Microglia enhance β‐amyloid peptide‐induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species

    Liya Qin;Yuxin Liu;Cynthia Cooper;Bin Liu

  • Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s Disease

    Wei Zhang;Kester Phillips;Albert R. Wielgus;Jie Liu

  • Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.

    Tongguang Wang;Liya Qin;Bin Liu;Yuxin Liu

  • Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase

    Wei Zhang;Tongguang Wang;Liya Qin;Hui-Ming Gao

  • Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures.

    Gwang-Ho Jeohn;Ling-Yuan Kong;Belinda Wilson;Pearlie Hudson

  • Systemic Infusion of Naloxone Reduces Degeneration of Rat Substantia Nigral Dopaminergic Neurons Induced by Intranigral Injection of Lipopolysaccharide

    Bin Liu;Jian-Wei Jiang;Belinda C. Wilson;Lina Du

  • Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra

    Z.-H Feng;T.-G Wang;D.-D Li;P Fung

  • Resveratrol Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity through Its Anti-Inflammatory Actions

    Feng Zhang;Jing-Shan Shi;Hui Zhou;Belinda C Wilson

  • Microglial PHOX and Mac‐1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha‐synuclein

    Wei Zhang;Shannon Dallas;Dan Zhang;Jian-Ping Guo

  • Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase

    Li Qian;Li Qian;Zongli Xu;Wei Zhang;Belinda Wilson

  • The role of microglia in paraquat-induced dopaminergic neurotoxicity.

    Xue Fei Wu;Michelle L. Block;Wei Zhang;Liya Qin;Liya Qin

Frequent Co-Authors

Jau-Shyong Hong
Jau-Shyong Hong National Institutes of Health
Michelle L. Block
Michelle L. Block Indiana University – Purdue University Indianapolis
Bin Liu
Bin Liu Australian National University
Xiaoming Hu
Xiaoming Hu University of Pittsburgh
Syed F. Ali
Syed F. Ali National Center for Toxicological Research
Guoying Bing
Guoying Bing University of Kentucky
Wei Zhang
Wei Zhang Central South University
Po See Chen
Po See Chen National Cheng Kung University
Michael K. McMillian
Michael K. McMillian Johnson & Johnson (United States)
Robert Langenbach
Robert Langenbach National Institutes of Health

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