Josefina Cano mainly focuses on Substantia nigra, Dopaminergic, Endocrinology, Internal medicine and Neuroscience. Her study in Substantia nigra is interdisciplinary in nature, drawing from both Striatum and Blood–brain barrier. The various areas that Josefina Cano examines in her Dopaminergic study include Tumor necrosis factor alpha, Inflammation, Microglia and Pharmacology.
Josefina Cano has included themes like Nigrostriatal pathway, Chronic stress, Neurodegeneration and Cell biology in her Microglia study. Her Endocrinology research is multidisciplinary, incorporating perspectives in Allosteric regulation and GABAA receptor. While the research belongs to areas of Neuroscience, Josefina Cano spends her time largely on the problem of Aquaporin 4, intersecting her research to questions surrounding Quinolinic acid, Lesion, Ion homeostasis, Axotomy and Evans Blue.
Her primary areas of investigation include Internal medicine, Endocrinology, Dopamine, Substantia nigra and Dopaminergic. In the subject of general Internal medicine, her work in Catecholamine, Neurotransmitter and Medial forebrain bundle is often linked to Turnover, thereby combining diverse domains of study. The study incorporates disciplines such as Monoamine neurotransmitter, Homovanillic acid and Serotonin in addition to Endocrinology.
Her Dopamine research integrates issues from Neurotoxicity and Biochemistry. Her Substantia nigra research incorporates elements of Tumor necrosis factor alpha, Immunology and Blood–brain barrier. Her work deals with themes such as Inflammation, Microglia, Neurodegeneration and Pharmacology, which intersect with Dopaminergic.
Josefina Cano focuses on Dopaminergic, Substantia nigra, Neurodegeneration, Microglia and Internal medicine. Neuroscience and Dopamine are closely tied to her Dopaminergic research. Her Substantia nigra study combines topics from a wide range of disciplines, such as Tumor necrosis factor alpha, Immunology, Transthyretin and Cerebrospinal fluid.
Her Neurodegeneration study integrates concerns from other disciplines, such as Inflammation and Pharmacology. Her Microglia research incorporates themes from Neuroinflammation and Glucocorticoid receptor, Glucocorticoid. Internal medicine is often connected to Endocrinology in her work.
Josefina Cano spends much of her time researching Dopaminergic, Substantia nigra, Neuroscience, Inflammation and Tumor necrosis factor alpha. Her research integrates issues of Oxidative stress and Risk factor in her study of Neuroscience. Her research investigates the link between Inflammation and topics such as Pharmacology that cross with problems in Neurodegeneration.
Her Neurodegeneration research is multidisciplinary, relying on both Immunology, Caspase 7 and Microglia. Her Tumor necrosis factor alpha research entails a greater understanding of Internal medicine. Her research investigates the connection between Neuroprotection and topics such as Protein kinase B that intersect with problems in Endocrinology.
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Caspase signalling controls microglia activation and neurotoxicity
Miguel A. Burguillos;Tomas Deierborg;Edel Kavanagh;Annette Persson.
Nature (2011)
The Single Intranigral Injection of LPS as a New Model for Studying the Selective Effects of Inflammatory Reactions on Dopaminergic System
A.J. Herrera;A. Castaño;J.L. Venero;J. Cano.
Neurobiology of Disease (2000)
Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system.
A. Castaño;A. J. Herrera;J. Cano;A. Machado.
Journal of Neurochemistry (2002)
Aquaporins in the central nervous system.
José L. Venero;Marı́a L. Vizuete;Alberto Machado;Josefina Cano.
Progress in Neurobiology (2001)
Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: potential role in brain edema.
M L Vizuete;J L Venero;C Vargas;A A Ilundáin.
Neurobiology of Disease (1999)
The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh‐TNF‐α, IL‐1β and IFN‐γ
A. Castaño;A. J. Herrera;J. Cano;A. Machado.
Journal of Neurochemistry (2002)
Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system.
Mayka Tomás-Camardiel;Inmaculada Rite;Antonio J Herrera;Rocio M de Pablos.
Neurobiology of Disease (2004)
Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex
R. M. de Pablos;R. F. Villarán;S. Argüelles;A. J. Herrera.
The Journal of Neuroscience (2006)
Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease.
Ruth F. Villarán;Ana M. Espinosa-Oliva;Manuel Sarmiento;Rocío M. De Pablos.
Journal of Neurochemistry (2010)
Detailed localization of aquaporin-4 messenger RNA in the CNS: preferential expression in periventricular organs.
J.L. Venero;M.L. Vizuete;A.A. Ilundáin;A. Machado.
Neuroscience (1999)
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