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Microbiology

D-Index
61
Citations
14887
World Ranking
2976
National Ranking
1183

Overview

Laura E. Via is affiliated with the National Institutes of Health in the United States and has a significant body of research within the field of medicine, focusing particularly on infectious diseases, immunology, and molecular biology. Their work primarily addresses topics related to tuberculosis research and epidemiology, Mycobacterium research and diagnosis, immune cell function and interaction, as well as SARS-CoV-2 and COVID-19 research and clinical studies.

They have published extensively, with frequent contributions appearing in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, SSRN Electronic Journal, Science Immunology, and Cell Reports. These publication platforms reflect a strong engagement with both preprint and peer-reviewed scientific literature.

Recent notable papers by Laura E. Via include:

  • PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques, 2021, Science Immunology
  • Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice, 2021, The Journal of Experimental Medicine
  • Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response, 2020, EJNMMI Research
  • Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection, 2022, Cell Reports
  • Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys, 2022, Cell

Their collaborative network includes frequent coauthors such as Clifton E. Barry, Daniel L. Barber, Keith D. Kauffman, Christine E. Nelson, and Danielle M. Weiner, indicating a consistent involvement in multidisciplinary teams across various studies.

Laura E. Via's research covers a spectrum of subfields, emphasizing infectious diseases, epidemiology, immunology, surgery, and molecular biology. The emphasis on tuberculosis is evident both in their publications and the predominant research topics they engage in, specifically tuberculosis research and epidemiology, Mycobacterium research and diagnosis, and diagnosis and treatment of tuberculosis.

Their work on immune response mechanisms, highlighted through studies on eosinophils and granulocyte responses, contributes to understanding host-pathogen interactions in tuberculosis and beyond. This focus intersects with investigations into COVID-19 and SARS-CoV-2, as shown in vaccine-related research.

Best Publications

  • A rapid CTAB DNA isolation technique useful for RAPD fingerprinting and other PCR applications.

    Stewart Cn;Via Le

  • Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

    Katrin D. Mayer-Barber;Bruno B. Andrade;Sandra D. Oland;Eduardo P. Amaral;Eduardo P. Amaral

  • Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates.

    Laura E. Via;P. Ling Lin;Sonja M. Ray;Jose Carrillo

  • Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7

    Laura E. Via;Dusanka Deretic;Roseann J. Ulmer;Nina S. Hibler

  • Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

    Seok Yong Eum;Ji Hye Kong;Min Sun Hong;Ye Jin Lee

  • The association between sterilizing activity and drug distribution into tuberculosis lesions

    Brendan Prideaux;Laura E. Via;Matthew D. Zimmerman;Seokyong Eum

  • Effects of cytokines on mycobacterial phagosome maturation

    L.E. Via;R.A. Fratti;M. McFalone;E. Pagan-Ramos

  • Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms

    Joshua T. Mattila;Olabisi O. Ojo;Diane Kepka-Lenhart;Simeone Marino

  • Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.

    Stephanus T Malherbe;Shubhada Shenai;Katharina Ronacher;Katharina Ronacher;Andre G Loxton;Andre G Loxton

  • Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

    Abigail L. Manson;Keira A. Cohen;Keira A. Cohen;Thomas Abeel;Thomas Abeel;Christopher A. Desjardins

  • Inflammatory signaling in human tuberculosis granulomas is spatially organized

    Mohlopheni J. Marakalala;Ravikiran M. Raju;Kirti Sharma;Yanjia J. Zhang

  • Prevalence of and risk factors for resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: a prospective cohort study

    Tracy Dalton;Peter Cegielski;Somsak Akksilp;Luis Asencios

  • Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis

    Keriann M Backus;Keriann M Backus;Helena I Boshoff;Conor S Barry;Omar Boutureira

  • Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene:implications for sensitivity to isoniazid

    V. Deretic;W. Philipp;S. Dhandayuthapani;M.H. Mudd

  • Green fluorescent protein as a marker for gene expression and cell biology of mycobacterial interactions with macrophages

    S. Dhandayuthapani;L.E. Via;C.A. Thomas;P.M. Horowitz

  • Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery

    Meenal Datta;Meenal Datta;Laura E. Via;Walid S. Kamoun;Chong Liu

  • Extreme Drug Tolerance of Mycobacterium tuberculosis in Caseum.

    Jansy P Sarathy;Laura E Via;Laura E Via;Danielle Weiner;Landry Blanc

  • Host blood RNA signatures predict the outcome of tuberculosis treatment

    Ethan G Thompson;Ying Du;Stephanus T Malherbe;Smitha Shankar

  • The wide utility of rabbits as models of human diseases

    Pedro J. Esteves;Joana Abrantes;Hanna Mari Baldauf;Lbachir BenMohamed

  • Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: A mechanistic model and tool for regimen and dose optimization

    Natasha Strydom;Sneha V. Gupta;William S. Fox;Laura E. Via

  • High Persister Mutants in Mycobacterium tuberculosis.

    Heather L. Torrey;Iris Keren;Laura E. Via;Jong Seok Lee

  • Pharmacokinetic Evaluation of the Penetration of Antituberculosis Agents in Rabbit Pulmonary Lesions

    Maria C. Kjellsson;Maria C. Kjellsson;Laura E. Via;Anne Goh;Danielle Weiner

  • Mutations in gidB Confer Low-Level Streptomycin Resistance in Mycobacterium tuberculosis

    Sharon Y. Wong;Jong Seok Lee;Hyun Kyung Kwak;Laura E. Via

Frequent Co-Authors

Clifton E. Barry
Clifton E. Barry National Institute of Allergy and Infectious Diseases
Sang-Nae Cho
Sang-Nae Cho Yonsei University
Véronique Dartois
Véronique Dartois Rutgers, The State University of New Jersey
Gerhard Walzl
Gerhard Walzl Stellenbosch University
Robert J. Wilkinson
Robert J. Wilkinson The Francis Crick Institute
Helena I. Boshoff
Helena I. Boshoff National Institutes of Health
JoAnne L. Flynn
JoAnne L. Flynn University of Pittsburgh
Vojo Deretic
Vojo Deretic University of New Mexico
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Philana Ling Lin
Philana Ling Lin University of Pittsburgh

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