World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
76
Citations
18647
World Ranking
18883
National Ranking
1704

Nicholas Topley publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Nicholas Topley sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 610 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 217 publications — 4th percentile

4% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Nicholas Topley D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Nicholas Topley sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 399 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 76 D-Index — 8th percentile

8% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Nicholas Topley is affiliated with Cardiff University in the United Kingdom. Their research spans multiple fields, primarily focusing on medicine, health professions, and computer science. Within these broad areas, their work delves into subfields such as artificial intelligence, immunology, nephrology, oncology, and health information management.

The scientist's publication record includes recent papers addressing topics related to dialysis, immune response, cytokine signaling, and machine learning applications in healthcare. Notable papers published by Nicholas Topley include:

  • Measurement of innate immune response biomarkers in peritoneal dialysis effluent using a rapid diagnostic point-of-care device as a diagnostic indicator of peritonitis, 2020, Kidney International
  • Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements, 2023, The Journal of Immunology
  • Barriers and facilitators to physical activity: A comparative analysis of transplant athletes competing in high intensity sporting events with other transplant recipients, 2024, PLoS ONE
  • Prediction of the infecting organism in peritoneal dialysis patients with acute peritonitis using interpretable Tsetlin Machines, 2024, Bioinformatics Advances
  • Prediction of the infecting organism in peritoneal dialysis patients with acute peritonitis using interpretable Tsetlin Machines, 2025, bioRxiv (Cold Spring Harbor Laboratory)

Topley's frequent collaborators include Matthias Eberl, David Millrine, Ana Cardus Figueras, Javier Uceda Fernandez, and Robert Andrews. Collaboration with these co-authors has produced multiple publications across different research topics.

The venues where Nicholas Topley publishes underline the diversity of their research. These include bioRxiv (Cold Spring Harbor Laboratory), Kidney International, The Journal of Immunology, PLoS ONE, and Bioinformatics Advances.

The principal topics addressed in their research cover:

  • Dialysis and renal disease management
  • Cytokine signaling pathways and interactions
  • Machine learning in healthcare
  • Artificial intelligence in healthcare
  • Central venous catheters and hemodialysis
  • Health systems, economic evaluations, quality of life
  • Immunodeficiency and autoimmune disorders

Nicholas Topley's work reflects an interdisciplinary approach combining clinical medicine with advanced computational techniques. Their focus on diagnostic technologies, inflammatory and immune mechanisms, and the application of interpretable machine learning methods highlights their contributions to both biomedical research and healthcare innovation.

Best Publications

  • Morphologic Changes in the Peritoneal Membrane of Patients with Renal Disease

    John David Williams;Kathrine Jane Craig;Nicholas Topley;Christopher John Von Ruhland

  • IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

    Suzanne Maria Hurst;Thomas S. Wilkinson;Rachel Mary McLoughlin;Suzanne Jones

  • The soluble interleukin 6 receptor: mechanisms of production and implications in disease

    Simon A. Jones;Sankichi Horiuchi;Nicholas Topley;Naoki Yamamoto

  • IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.

    Ceri Alan Fielding;Rachel Mary McLoughlin;Louise McLeod;Chantal Sophie Colmont

  • The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane

    John David Williams;Nicholas Topley;Kathrine Jane Craig;Ruth Kathryn MacKenzie

  • Encapsulating peritoneal sclerosis : Definition, etiology, diagnosis, and treatment

    Yoshindo Kawaguchi;Hideki Kawanishi;Salim Mujais;Nicholas Topley

  • IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation

    Rachel Mary McLoughlin;Brendan J. Jenkins;Dianne Grail;Anwen Sian Williams

  • Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation

    Ceri A. Fielding;Gareth Wyn Jones;Rachel Mary McLoughlin;Louise McLeod

  • Interleukin 1-α and tumor necrosis factor-α induce oxygen radical production in mesangial cells

    Heinfried H. Radeke;Beate Meier;Nicholas Topley;Jürgen Flöge

  • Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

    Brendan John Jenkins;Dianne Grail;Thao Nheu;Meri Najdovska

  • Soluble IL-6 Receptor Governs IL-6 Activity in Experimental Arthritis: Blockade of Arthritis Severity by Soluble Glycoprotein 130

    Mari Ann Nowell;Peter James Richards;Sankichi Horiuchi;Naoki Yamamoto

  • Interplay between IFN-γ and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

    Rachel Mary McLoughlin;Janusz Witowski;Rachel L. Robson;Thomas S. Wilkinson

  • Encapsulating peritoneal sclerosis: definition, etiology, diagnosis, and treatment. International Society for Peritoneal Dialysis Ad Hoc Committee on Ultrafiltration Management in Peritoneal Dialysis.

    Kawaguchi Y;Kawanishi H;Mujais S;Topley N

  • The Pathophysiology of the Peritoneal Membrane

    Olivier Devuyst;Peter J. Margetts;Nicholas Topley

  • Human peritoneal mesothelial cells synthesize interleukin-6: Induction by IL-1β and TNFα

    Nicholas Topley;Achim Jörres;Werner Luttmann;Meryl M. Petersen

  • Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis.

    Mari Ann Nowell;Anwen Sian Williams;Sara Madelaine Carty;Jurgen Scheller

  • Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling

    Xiao Liang Zhang;Nicholas Topley;Takafumi Ito;Aled Owain Phillips

  • Regulation of pre–B cell colony‐enhancing factor by STAT‐3–dependent interleukin‐6 trans‐signaling: Implications in the pathogenesis of rheumatoid arthritis

    Mari Ann Nowell;Peter James Richards;Ceri Alan Fielding;Simona Ognjanovic

  • Loss of CD4+ T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 Trans Signaling in the Local Maintenance of Th17 Cells

    Gareth Wyn Jones;Rachel Mary McLoughlin;Victoria Jayne Hammond;Clare Rhian Parker

  • The effect of dialysate on peritoneal phagocyte oxidative metabolism

    Nicholas Topley;Haifa M.M. Alobaidi;Malcolm Davies;Gerald A. Coles

Frequent Co-Authors

Simon Arnett Jones
Simon Arnett Jones Cardiff University
Matthias Eberl
Matthias Eberl Cardiff University
Philip R. Taylor
Philip R. Taylor Cardiff University
Brendan J. Jenkins
Brendan J. Jenkins Hudson Institute of Medical Research
Simon Jones
Simon Jones Microsoft (United States)
Valerie B. O'Donnell
Valerie B. O'Donnell Cardiff University
Matthias Ernst
Matthias Ernst La Trobe University
Stefan Rose-John
Stefan Rose-John Kiel University
Olivier Devuyst
Olivier Devuyst University of Zurich
Edward Chung Yern Wang
Edward Chung Yern Wang Cardiff University

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