World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
13445
World Ranking
17458
National Ranking
499

Overview

Brendan J. Jenkins is affiliated with the Hudson Institute of Medical Research in Australia. Their research primarily encompasses fields related to Medicine and Immunology and Microbiology, with a notable focus on Oncology, Immunology, Surgery, Cancer Research, and Molecular Biology.

The scientist's main areas of study include:

  • Pancreatic and Hepatic Oncology Research
  • Cytokine Signaling Pathways and Interactions
  • Helicobacter pylori-related gastroenterology studies
  • Cancer Genomics and Diagnostics
  • IL-33, ST2, and ILC Pathways
  • Inflammasome and immune disorders
  • Immune cells in cancer

The research output includes multiple publications in frequent venues such as:

  • Cytokine
  • Oncogene
  • Gastroenterology
  • Methods in Molecular Biology
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent representative papers are:

  • Targeting IL-6 trans-signalling: past, present and future prospects, 2023, Nature Reviews Immunology
  • Context-dependent functions of pattern recognition receptors in cancer, 2022, Nature Reviews Cancer
  • Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma, 2020, Cancers
  • Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma, 2022, Science Translational Medicine
  • IL-6 family cytokines in respiratory health and disease, 2021, Cytokine

Collaboration is evident through frequent co-authors, including:

  • Joanne Lundy
  • Daniel Croagh
  • Mohamed I. Saad
  • Louise McLeod
  • Ruby Dawson

Best Publications

  • A family of cytokine-inducible inhibitors of signalling

    Robyn Starr;Tracy A. Willson;Elizabeth M. Viney;Leecia J. L. Murray

  • Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer

    Simon A. Jones;Brendan J. Jenkins

  • Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

    Niall C. Tebbutt;Andrew S. Giraud;Melissa Inglese;Brendan Jenkins

  • IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.

    Ceri Alan Fielding;Rachel Mary McLoughlin;Louise McLeod;Chantal Sophie Colmont

  • IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation

    Rachel Mary McLoughlin;Brendan J. Jenkins;Dianne Grail;Anwen Sian Williams

  • STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice

    Matthias Ernst;Meri Najdovska;Dianne Grail;Therese Lundgren-May

  • Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation

    Ceri A. Fielding;Gareth Wyn Jones;Rachel Mary McLoughlin;Louise McLeod

  • Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

    Brendan John Jenkins;Dianne Grail;Thao Nheu;Meri Najdovska

  • Acquiring signalling specificity from the cytokine receptor gp130

    Matthias Ernst;Brendan J Jenkins

  • IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3

    Claire J Greenhill;Stefan Rose-John;Rami Lissilaa;Walter Ferlin

  • STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation

    Hazel Tye;Catherine L. Kennedy;Meri Najdovska;Louise McLeod

  • Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis.

    Mari Ann Nowell;Anwen Sian Williams;Sara Madelaine Carty;Jurgen Scheller

  • Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways

    Natalie A. Sims;Brendan J. Jenkins;Julian M.W. Quinn;Akira Nakamura

  • Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

    Louise M. Judd;Barbara M. Alderman;Meegan Howlett;Arthur Shulkes

  • Interleukin-11 receptor signaling is required for normal bone remodeling

    Natalie A. Sims;Brendan J. Jenkins;Akira Nakamura;Julian M. W. Quinn

  • STAT3 Activation Regulates Growth, Inflammation, and Vascularization in a Mouse Model of Gastric Tumorigenesis

    Louise M. Judd;Karin Bredin;Anastasia Kalantzis;Brendan J. Jenkins

  • STAT1 plays a role in TLR signal transduction and inflammatory responses

    Kevin Luu;Claire J Greenhill;Andrea Majoros;Thomas Decker

  • Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

    Lin Luo;Adam A Wall;Jeremy C Yeo;Nicholas D Condon

  • Scaffolding Protein Gab2 Mediates Differentiation Signaling Downstream of Fms Receptor Tyrosine Kinase

    Yan Liu;Brendan Jenkins;Jung Lim Shin;Larry R. Rohrschneider

  • Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis

    Brendan John Jenkins;Brendan John Jenkins;Andrew W Roberts;Claire J Greenhill;Meri Najdovska

Frequent Co-Authors

Matthias Ernst
Matthias Ernst La Trobe University
Stefan Rose-John
Stefan Rose-John Kiel University
Gary P. Anderson
Gary P. Anderson University of Melbourne
Steven Bozinovski
Steven Bozinovski RMIT University
Ross Vlahos
Ross Vlahos RMIT University
Simon Arnett Jones
Simon Arnett Jones Cardiff University
Paul J. Hertzog
Paul J. Hertzog Hudson Institute of Medical Research
Nicholas Topley
Nicholas Topley Cardiff University
Patrick Tan
Patrick Tan Duke NUS Graduate Medical School
Richard L. Ferrero
Richard L. Ferrero Hudson Institute of Medical Research

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