Peter C. Heinrich

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Germany Leader Award
• 2025 - Research.com Biology and Biochemistry in Germany Leader Award
• 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Best Publications

• Principles of interleukin (IL)-6-type cytokine signalling and its regulation.

  Peter C Heinrich;Iris Behrmann;Serge Haan;Heike M Hermanns

  4070
  Citations

• Interleukin-6 and the acute phase response

  P C Heinrich;J V Castell;T Andus

  3842
  Citations

• INTERLEUKIN-6-TYPE CYTOKINE SIGNALLING THROUGH THE GP130/JAK/STAT PATHWAY

  Peter C. Heinrich;Iris Behrmann;Gerhard Müller-Newen;Fred Schaper

  2817
  Citations

• Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes

  José V. Castell;Maria J. Gómez-Lechón;Martina David;Tilo Andus

  1157
  Citations

• Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

  Claudia Lütticken;Ursula M. Wegenka;Juping Yuan;Jan Buschmann

  1031
  Citations

• Acute-phase response of human hepatocytes: regulation of acute-phase protein synthesis by interleukin-6.

  José V. Castell;Maria José Gómez-lechón;Martina David;Ricardo Fabra

  1002
  Citations

• Soluble receptors for cytokines and growth factors: generation and biological function

  S Rose-John;P C Heinrich

  956
  Citations

• Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.

  U M Wegenka;J Buschmann;C Lütticken;P C Heinrich

  751
  Citations

• The soluble interleukin‐6 receptor is generated by shedding

  Müllberg J;Schooltink H;Stoyan T;Günther M

  631
  Citations

• Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes.

  José V. Castell;Maria J. Gómez-Lechón;Martina David;Toshio Hirano

  624
  Citations

• A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

  D Guschin;N Rogers;J Briscoe;B Witthuhn

  567
  Citations

• Induction of rat acute-phase proteins by interleukin 6 in vivo.

  Thomas Geiger;Tilo Andus;Jan Klapproth;Toshio Hirano

  543
  Citations

• SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.

  Jochen Schmitz;Manuela Weissenbach;Serge Haan;Peter C. Heinrich

  528
  Citations

• Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins.

  A Mackiewicz;H Schooltink;P C Heinrich;S Rose-John

  479
  Citations

• Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 I. DEFINITION OF A NOVEL PHOSPHOTYROSINE MOTIF MEDIATING STAT1 ACTIVATION

  Claudia Gerhartz;Birgit Heesel;Jürgen Sasse;Ulrike Hemmann

  454
  Citations

• Hepatic acute phase proteins--regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling.

  Johannes G. Bode;Ute Albrecht;Dieter Häussinger;Peter C. Heinrich;Peter C. Heinrich

  442
  Citations

• Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis

  Mark M. Neis;Bettina Peters;Alexandra Dreuw;Joerg Wenzel

  441
  Citations

• Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3

  Claudia Niemand;Ariane Nimmesgern;Serge Haan;Patrick Fischer

  436
  Citations

• IFN-α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3

  Johannes G Bode;Stephan Ludwig;Christina Ehrhardt;Ute Albrecht

  418
  Citations

• Recombinant human B cell stimulatory factor 2 (BSF-2/IFN-β2) regulates β-fibrinogen and albumin mRNA levels in Fao-9 cells

  Tilo Andus;Thomas Geiger;Toshio Hirano;Hinnak Northoff

  416
  Citations