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D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
15740
World Ranking
18550
National Ranking
1268

Overview

Fred Schaper is a researcher affiliated with Otto-von-Guericke University Magdeburg in Germany. Their work spans multiple fields, primarily focusing on biochemistry, genetics, molecular biology, medicine, and materials science.

Their research encompasses several subfields, including molecular biology, oncology, biomedical engineering, electronic, optical and magnetic materials, and biomaterials. Schaper's studies engage deeply with topics such as cytokine signaling pathways and interactions, gold and silver nanoparticles synthesis and applications, nanoparticle-based drug delivery systems, biosensors and analytical detection methods, protein tyrosine phosphatases, galectins and cancer biology, and gene regulatory network analysis.

Schaper has contributed to multiple scientific articles published in diverse research venues. Some recent papers include:

  • "The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling," 2021, Cell Communication and Signaling
  • "Glucocorticoids attenuate interleukin-6-induced c-Fos and Egr1 expression and impair neuritogenesis in PC12 cells," 2021, Journal of Neurochemistry
  • "All-in-one superparamagnetic and SERS-active niosomes for dual-targeted in vitro detection of breast cancer cells," 2022, Sensors & Diagnostics
  • "Decoding cellular communication: An information theoretic perspective on cytokine and endocrine signaling," 2022, Current Opinion in Endocrine and Metabolic Research
  • "Non-canonical STAT3 function reduces REDD1 transcription," 2022, FEBS Journal

Frequent co-authors collaborating with Schaper include Anna Dittrich, Nicole Wundrack, Tomasz Jetka, Viktor Maurer, and Ajmal Zarinwall.

The publication venues featuring Schaper's work frequently are:

  • Cell Communication and Signaling
  • Current Opinion in Endocrine and Metabolic Research
  • Journal of Neurochemistry
  • Sensors & Diagnostics
  • FEBS Journal

Best Publications

  • Principles of interleukin (IL)-6-type cytokine signalling and its regulation.

    Peter C Heinrich;Iris Behrmann;Serge Haan;Heike M Hermanns

  • INTERLEUKIN-6-TYPE CYTOKINE SIGNALLING THROUGH THE GP130/JAK/STAT PATHWAY

    Peter C. Heinrich;Iris Behrmann;Gerhard Müller-Newen;Fred Schaper

  • Interleukin-6: Biology, signaling and strategies of blockade.

    Fred Schaper;Stefan Rose-John

  • SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.

    Jochen Schmitz;Manuela Weissenbach;Serge Haan;Peter C. Heinrich

  • Hepatic acute phase proteins--regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling.

    Johannes G. Bode;Ute Albrecht;Dieter Häussinger;Peter C. Heinrich;Peter C. Heinrich

  • Plasticity and cross-talk of interleukin 6-type cytokines.

    Christoph Garbers;Heike M. Hermanns;Fred Schaper;Gerhard Müller-Newen

  • Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3

    Claudia Niemand;Ariane Nimmesgern;Serge Haan;Patrick Fischer

  • IFN-α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3

    Johannes G Bode;Stephan Ludwig;Christina Ehrhardt;Ute Albrecht

  • SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130

    Ute Lehmann;Jochen Schmitz;Manuela Weissenbach;Radoslaw M. Sobota

  • LPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages

    Johannes G. Bode;Ariane Nimmesgern;Jochen Schmitz;Fred Schaper

  • Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.

    Fred Schaper;Cornelia Gendo;Monika Eck;Jochen Schmitz

  • Expression of suppressors of cytokine signaling during liver regeneration.

    Jean S. Campbell;Lisa Prichard;Fred Schaper;Jochen Schmitz

  • Phosphorylation Events Modulate the Ability of Interferon Consensus Sequence Binding Protein to Interact with Interferon Regulatory Factors and to Bind DNA

    Rakefet Sharf;David Meraro;Aviva Azriel;Angela M. Thornton

  • Interleukin-6 signalling: more than Jaks and STATs.

    René Eulenfeld;Anna Dittrich;Anna Dittrich;Christina Khouri;Pia J. Müller

  • Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes

    Sabine Kirchhoff;Fred Schaper;Hansjörg Hauser

  • The zinc finger protein Gfi‐1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

    Bernd Rödel;Kamiab Tavassoli;Holger Karsunky;Thorsten Schmidt

  • Different protein turnover of interleukin-6-type cytokine signalling components.

    Elmar Siewert;Werner Müller-Esterl;Robin Starr;Peter C. Heinrich

  • IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR.

    S Kirchhoff;A E Koromilas;F Schaper;M Grashoff

  • Interleukin-6 is a direct mediator of T cell migration

    Manuela Weissenbach;Thomas Clahsen;Christian Weber;Dirk Spitzer

  • Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-α Involves Activation of the MKK6/p38MAPK/MK2 Cascade

    Christian Ehlting;Wi S. Lai;Fred Schaper;Erwin D. Brenndörfer

Frequent Co-Authors

Peter C. Heinrich
Peter C. Heinrich University of Freiburg
Gerhard Müller-Newen
Gerhard Müller-Newen RWTH Aachen University
Iris Behrmann
Iris Behrmann University of Luxembourg
Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Stephan Ludwig
Stephan Ludwig University of Münster
Stefan Rose-John
Stefan Rose-John Kiel University
Jens Schneider-Mergener
Jens Schneider-Mergener Humboldt-Universität zu Berlin
Matthias Gaestel
Matthias Gaestel Hannover Medical School
Jan Tavernier
Jan Tavernier Ghent University
Rolf Findeisen
Rolf Findeisen Technical University of Darmstadt

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