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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
47926
World Ranking
999
National Ranking
25

Medicine

D-Index
109
Citations
47903
World Ranking
5739
National Ranking
156

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award
  • 2015 - Fellow of the Australian Academy of Health and Medical Science

Overview

Nicos A. Nicola is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research focus spans multiple fields primarily within medicine and immunology and microbiology, with a significant contribution to subfields such as immunology, molecular biology, oncology, hematology, and genetics.

The scientist's work extensively addresses topics including immunotherapy and immune responses, cytokine signaling pathways and interactions, platelet disorders and treatments, myeloproliferative neoplasms diagnosis and treatment, RNA interference and gene delivery, medicinal plant pharmacodynamics research, and interferon and immune responses.

Nicos A. Nicola has published in various scientific journals, with notable publications in the following venues:

  • eLife
  • Cytokine
  • Nature Communications
  • PROTEOMICS
  • Communications Biology

Their recent papers include:

  • RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells, 2020, eLife
  • The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo, 2023, Cytokine
  • Proteomic analyses reveal that immune integrins are major targets for regulation by Membrane-Associated Ring-CH (MARCH) proteins MARCH2, 3, 4 and 9, 2021, PROTEOMICS
  • Structure guided studies of the interaction between PTP1B and JAK, 2023, Communications Biology
  • Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin, 2024, Nature Communications

Nicos A. Nicola collaborates frequently with other researchers, including:

  • Jeffrey J. Babon
  • Nadia J. Kershaw
  • Warren S. Alexander
  • Andrew J. Kueh
  • Narelle Keating

In recognition of contributions to the field, they were named a Fellow of the Australian Academy of Health and Medical Science in 2015.

Best Publications

  • A family of cytokine-inducible inhibitors of signalling

    Robyn Starr;Tracy A. Willson;Elizabeth M. Viney;Leecia J. L. Murray

  • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

    R L Williams;D J Hilton;S Pease;T A Willson

  • The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

    James M. Murphy;Peter E. Czabotar;Peter E. Czabotar;Joanne M. Hildebrand;Joanne M. Hildebrand;Isabelle S. Lucet

  • SOCS3 negatively regulates IL-6 signaling in vivo.

    Ben A Croker;Danielle L Krebs;Jian-Guo Zhang;Sam Wormald

  • Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

    Timothy Gainsford;Tracy A. Willson;Donald Metcalf;Emanuela Handman

  • SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

    Warren S Alexander;Robyn Starr;Robyn Starr;Jennifer E Fenner;Clare L Scott;Clare L Scott

  • Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

    D.P. Gearing;J.A. King;N.M. Gough;N.A. Nicola

  • Twenty proteins containing a C-terminal SOCS box form five structural classes

    Douglas J. Hilton;Rachael T. Richardson;Warren S. Alexander;Elizabeth M. Viney

  • The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

    Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson

  • Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor.

    N A Nicola;D Metcalf;M Matsumoto;G R Johnson

  • Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF).

    D P Gearing;N M Gough;J A King;D J Hilton

  • Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl

    Warren S. Alexander;Andrew W. Roberts;Nicos A. Nicola;Ruili Li

  • Gigantism in mice lacking suppressor of cytokine signalling-2

    Donald Metcalf;Christopher J. Greenhalgh;Elizabeth Viney;Tracy A. Willson

  • Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

    Sandra E. Nicholson;David De Souza;Louis J. Fabri;Jason Corbin

  • Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor.

    Metcalf D;Begley Cg;Johnson Gr;Nicola Na

  • Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor

    Nicholas M Gough;Jill Gough;Donald Metcalf;Anne Kelso

  • The SOCS box: a tale of destruction and degradation

    Benjamin T Kile;Brenda A Schulman;Warren S Alexander;Nicos A Nicola

  • Hemopoietic cell growth factors and their receptors.

    Nicos A. . Nicola

  • Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

    Sandra E. Nicholson;Tracy A. Willson;Alison Farley;Robyn Starr

  • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

    Douglas J. Hilton;Jian-Guo Zhang;Donald Metcalf;Warren S. Alexander

Frequent Co-Authors

Douglas J. Hilton
Douglas J. Hilton Walter and Eliza Hall Institute of Medical Research
Donald Metcalf
Donald Metcalf Walter and Eliza Hall Institute of Medical Research
Warren S. Alexander
Warren S. Alexander Walter and Eliza Hall Institute of Medical Research
Jian-Guo Zhang
Jian-Guo Zhang Beijing Institute for Brain Disorders
Jeffrey J. Babon
Jeffrey J. Babon Walter and Eliza Hall Institute of Medical Research
Sandra E. Nicholson
Sandra E. Nicholson Walter and Eliza Hall Institute of Medical Research
Tracy A. Willson
Tracy A. Willson Walter and Eliza Hall Institute of Medical Research
Richard J. Simpson
Richard J. Simpson La Trobe University
Antony W. Burgess
Antony W. Burgess Walter and Eliza Hall Institute of Medical Research
Andrew W. Roberts
Andrew W. Roberts Walter and Eliza Hall Institute of Medical Research

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