World's Best Scientists 2026 revealed!
Edward Chung Yern Wang

Edward Chung Yern Wang

D-Index & Metrics

Microbiology

D-Index
45
Citations
7262
World Ranking
5031
National Ranking
426

Overview

Edward Chung Yern Wang is affiliated with Cardiff University in the United Kingdom. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these areas, they have focused on several key subfields including Epidemiology, Immunology, Molecular Biology, Infectious Diseases, and Virology.

Their scholarly output covers a variety of topics, notably immune cell function and interaction, cytomegalovirus and herpesvirus research, herpesvirus infections and treatments, SARS-CoV-2 and COVID-19 research, interferon and immune responses, COVID-19 clinical research studies, and Toxoplasma gondii research studies.

Edward Chung Yern Wang has contributed to multiple papers, some of which include:

  • A prenylated dsRNA sensor protects against severe COVID-19 (2021, Science)
  • SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies (2022, eLife)
  • Double-stranded RNA reduction by chaotropic agents during in vitro transcription of messenger RNA (2022, Molecular Therapy - Nucleic Acids)
  • Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus (2021, Journal of Clinical Investigation)
  • CD57+ Memory T Cells Proliferate In Vivo (2020, Cell Reports)

Their frequent collaborators include Richard J. Stanton, Ceri A. Fielding, Michael P. Weekes, David A. Price, and Gavin W. G. Wilkinson. Collaboration patterns suggest a multidisciplinary approach to virology and immunology research.

Their research has been published across several venues, with multiple articles appearing in bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Journal of Clinical Investigation, Journal of General Virology, and Science.

Best Publications

  • Quantitative temporal viromics: an approach to investigate host-pathogen interaction.

    Michael P. Weekes;Michael P. Weekes;Peter Tomasec;Edward L. Huttlin;Ceri Alan Fielding

  • Downregulation of natural killer cell–activating ligand CD155 by human cytomegalovirus UL141

    Peter Tomasec;Edward Chung Yern Wang;Andrew J. Davison;Borivoj Vojtesek

  • Modulation of natural killer cells by human cytomegalovirus

    Gavin William Grahame Wilkinson;Peter Tomasec;Richard James Stanton;Melanie Armstrong

  • Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment.

    Paul J. Lehner;Eddie C. Y. Wang;Paul A. H. Moss;Sheila Williams

  • The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases

    Françoise Meylan;Todd S. Davidson;Erin Kahle;Michelle Kinder

  • A prenylated dsRNA sensor protects against severe COVID-19.

    Arthur Wickenhagen;Elena Sugrue;Spyros Lytras;Srikeerthana Kuchi

  • The Switch from Latent to Productive Infection in Epstein-Barr Virus-Infected B Cells Is Associated with Sensitization to NK Cell Killing

    Isabel Y. Pappworth;Eddie C. Wang;Martin Rowe;Martin Rowe

  • CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus.

    E. C. Y. Wang;P. A. H. Moss;P. Frodsham;P. J. Lehner

  • UL40-mediated NK evasion during productive infection with human cytomegalovirus

    Edward Chung Yern Wang;Brian Patrick McSharry;Christelle Retiere;Peter Tomasec

  • CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia

    Steven Coles;Edward Chung Yern Wang;Stephen Tzekwung Man;Robert Kerrin Hills

  • The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.

    Virginie Prod'homme;Cora Griffin;Rebecca Aicheler;Edward Chung Yern Wang

  • DR3 regulates negative selection during thymocyte development.

    Edward Chung Yern Wang;Anette Thern;Angela Denzel;Jeremy Kitson

  • The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis

    Melanie Jane Bull;Anwen Siân Williams;Zarabeth Mecklenburgh;Claudia Jane Calder

  • Human cytomegalovirus: taking the strain.

    Gavin William Grahame Wilkinson;Andrew J. Davison;Peter Tomasec;Ceri Alan Fielding

  • Subsets of CD8 +, CD57+ cells in normal, healthy individuals: correlations with human cytomegalovirus (HCMV) carrier status, phenotypic and functional analyses

    E. C. Y. Wang;J. Taylor-Wiedeman;P. Perera;J. Fisher

  • Adenovirus E3/19K Promotes Evasion of NK Cell Recognition by Intracellular Sequestration of the NKG2D Ligands Major Histocompatibility Complex Class I Chain-Related Proteins A and B

    Brian P. McSharry;Hans-Gerhard Burgert;Douglas P. Owen;Richard James Stanton

  • Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation

    Ceri Alan Fielding;Rebecca Aicheler;Richard J. Stanton;Edward Chung Yern Wang

  • Human Cytomegalovirus UL40 Signal Peptide Regulates Cell Surface Expression of the NK Cell Ligands HLA-E and gpUL18

    Virginie Prod'homme;Peter Tomasec;Charles Cunningham;Marius K. Lemberg

  • High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms.

    Katie Nightingale;Kai-Min Lin;Benjamin J. Ravenhill;Colin Davies

  • The measurement of stress-related immune dysfunction in psychoneuroimmunology

    K Vedhara;J.D Fox;E.C.Y Wang

Frequent Co-Authors

Andrew J. Davison
Andrew J. Davison University of Glasgow
Paul J. Lehner
Paul J. Lehner University of Cambridge
Aymen Al-Shamkhani
Aymen Al-Shamkhani University of Southampton
Nicholas Topley
Nicholas Topley Cardiff University
Simon Arnett Jones
Simon Arnett Jones Cardiff University
Awen Gallimore
Awen Gallimore Cardiff University
Alan Kenneth Burnett
Alan Kenneth Burnett University of Glasgow
Robin Antrobus
Robin Antrobus University of Cambridge
Andrew James Godkin
Andrew James Godkin Cardiff University

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