What is he best known for?
The fields of study he is best known for:
John Sinclair mostly deals with Human cytomegalovirus, Virology, Molecular biology, Immunology and Cellular differentiation.
He performs multidisciplinary studies into Human cytomegalovirus and Latency in his work.
His Virology research is multidisciplinary, incorporating perspectives in Transcriptional regulation, General transcription factor, TATA-Box Binding Protein and Monocyte.
His biological study spans a wide range of topics, including HIV Long Terminal Repeat, Binding protein, Heterologous, Transfection and Promoter.
His work on Virus as part of general Immunology research is frequently linked to Peripheral blood mononuclear cell and Population, thereby connecting diverse disciplines of science.
His research integrates issues of Regulation of gene expression and Immediate early protein in his study of Cellular differentiation.
His most cited work include:
- Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells. (616 citations)
- Latency and reactivation of human cytomegalovirus. (355 citations)
- Detection of endogenous human cytomegalovirus in CD34+ bone marrow progenitors. (302 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Human cytomegalovirus, Virology, Immunology, Virus and Molecular biology.
John Sinclair performs integrative study on Human cytomegalovirus and Latency in his works.
His Virology research incorporates elements of Gene expression and Cellular differentiation.
Many of his research projects under Immunology are closely connected to Betaherpesvirinae and Population with Betaherpesvirinae and Population, tying the diverse disciplines of science together.
His work deals with themes such as Transcription factor, Gene, Immediate early protein and Promoter, TATA box, which intersect with Molecular biology.
His Virus latency study integrates concerns from other disciplines, such as Congenital cytomegalovirus infection and Regulation of gene expression.
He most often published in these fields:
- Human cytomegalovirus (72.97%)
- Virology (59.46%)
- Immunology (22.52%)
What were the highlights of his more recent work (between 2014-2021)?
- Human cytomegalovirus (72.97%)
- Virology (59.46%)
- Immune system (16.22%)
In recent papers he was focusing on the following fields of study:
John Sinclair focuses on Human cytomegalovirus, Virology, Immune system, Lytic cycle and Myeloid.
His Human cytomegalovirus study necessitates a more in-depth grasp of Virus.
His studies deal with areas such as Haematopoiesis, Stem cell and Single-cell analysis as well as Virology.
His research in Immune system intersects with topics in S100A8, Antibody and Chemotaxis.
His Lytic cycle study combines topics in areas such as Cell, Gene expression and Cellular differentiation.
In his study, which falls under the umbrella issue of Myeloid, Bone marrow, CD34 and Tropism is strongly linked to Cell type.
Between 2014 and 2021, his most popular works were:
- Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing. (79 citations)
- Sleepless latency of human cytomegalovirus (62 citations)
- The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies? (59 citations)
In his most recent research, the most cited papers focused on:
Human cytomegalovirus, Virology, Lytic cycle, Immune system and Virus are his primary areas of study.
Human cytomegalovirus is a subfield of Immunology that he explores.
The study incorporates disciplines such as RNA, Pathogen and Transcriptome, Gene expression in addition to Lytic cycle.
His work carried out in the field of Virus brings together such families of science as Secretion, Cancer research and microRNA.
As part of the same scientific family, John Sinclair usually focuses on CD14, concentrating on Cell biology and intersecting with Cytokine, Dendritic cell, Monocyte and Interleukin 10.
His Myeloid research includes elements of Regulation of gene expression, Viral life cycle, GATA2 and Antigen.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
