World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
73
Citations
23911
World Ranking
2020
National Ranking
922

Research.com Recognitions

  • 2016 - Fellow of the American Statistical Association (ASA)

Overview

Ingo Ruczinski is affiliated with Johns Hopkins University in the United States. Their research spans significant areas within medicine, biochemistry, genetics, and molecular biology, with a strong focus on genetics and molecular biology subfields. They have contributed extensively to infectious diseases, physiology, and pulmonary and respiratory medicine.

Ruczinski's work covers various main topics, including:

  • Genetic Associations and Epidemiology
  • Asthma and respiratory diseases
  • Monoclonal and Polyclonal Antibodies Research
  • Cleft Lip and Palate Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Food Allergy and Anaphylaxis Research
  • Craniofacial Disorders and Treatments

Their published research includes notable papers such as:

  • "Genome-wide Enrichment of De Novo Coding Mutations in Orofacial Cleft Trios," 2020, The American Journal of Human Genetics
  • "Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality," 2021, Journal of Clinical Investigation
  • "Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants," 2020, Nature Communications
  • "Pleiotropy method reveals genetic overlap between orofacial clefts at multiple novel loci from GWAS of multi-ethnic trios," 2021, PLoS Genetics
  • "Protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study," 2020, Thorax

Ruczinski has collaborated frequently with several co-authors, including:

  • Rasika A. Mathias
  • Margaret A. Taub
  • Kathleen C. Barnes
  • Kai Kammers
  • H. Benjamin Larman

Their research has been published regularly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Journal of Allergy and Clinical Immunology
  • Nature Communications
  • Frontiers in Immunology

Ruczinski was awarded the title of Fellow of the American Statistical Association (ASA) in 2016.

Best Publications

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

    Dara G. Torgerson;Dara G. Torgerson;Elizabeth J. Ampleford;Grace Y. Chiu;W. James Gauderman

  • Random-coil behavior and the dimensions of chemically unfolded proteins

    Jonathan E. Kohn;Ian S. Millett;Jaby Jacob;Jaby Jacob;Bojan Zagrovic

  • Ab initio protein structure prediction of CASP III targets using ROSETTA

    Kim T. Simons;Rich Bonneau;Ingo Ruczinski;David Baker

  • Multiple loci associated with indices of renal function and chronic kidney disease

    Anna Köttgen;Nicole L. Glazer;Abbas Dehghan;Shih Jen Hwang

  • A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4

    Terri H. Beaty;Jeffrey C. Murray;Mary L. Marazita;Ronald G. Munger

  • Detectable clonal mosaicism from birth to old age and its relationship to cancer.

    Cathy C. Laurie;Cecelia A Laurie;Kenneth Rice;Kimberly F. Doheny

  • Sensitive detection of chromosomal segments of distinct ancestry in admixed populations.

    Alkes L. Price;Arti Tandon;Arti Tandon;Nick Patterson;Kathleen C Barnes

  • Improved recognition of native-like protein structures using a combination of sequence-dependent and sequence-independent features of proteins.

    Kim T. Simons;Ingo Ruczinski;Charles Kooperberg;Brian A. Fox

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Experiment and theory highlight role of native state topology in SH3 folding.

    David S. Riddle;David S. Riddle;Viara P. Grantcharova;Jed V. Santiago;Eric Alm

  • Topology, stability, sequence, and length: Defining the determinants of two-state protein folding kinetics

    Kevin W. Plaxco;Kim T. Simons;Ingo Ruczinski;David Baker

  • Rosetta in CASP4: Progress in ab initio protein structure prediction

    Richard Bonneau;Jerry Tsai;Ingo Ruczinski;Dylan Chivian

  • Variants of DENND1B Associated with Asthma in Children

    Patrick M. A. Sleiman;James Flory;Marcin Imielinski;Jonathan P. Bradfield

  • Assembly of a pan-genome from deep sequencing of 910 humans of African descent

    Rachel M. Sherman;Juliet Forman;Juliet Forman;Valentin Antonescu;Daniela Puiu

  • Genome-wide Association Analysis Identifies PDE4D as an Asthma-Susceptibility Gene

    Blanca E. Himes;Gary M. Hunninghake;James W. Baurley;Nicholas M. Rafaels

  • Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

    Kerstin U. Ludwig;Elisabeth Mangold;Stefan Herms;Stefanie Nowak;Stefanie Nowak

  • Identifying interacting SNPs using Monte Carlo logic regression.

    Charles Kooperberg;Ingo Ruczinski

  • Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

    Richa Saxena;Richa Saxena;Clara C. Elbers;Clara C. Elbers;Yiran Guo;Inga Peter

  • Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Louise V. Wain;Louise V. Wain;Nick Shrine;María Soler Artigas;A. Mesut Erzurumluoglu

Frequent Co-Authors

Rasika A. Mathias
Rasika A. Mathias Johns Hopkins University
Terri H. Beaty
Terri H. Beaty Johns Hopkins University
Kathleen C. Barnes
Kathleen C. Barnes University of Colorado Denver
Nicholas Rafaels
Nicholas Rafaels University of Colorado Denver
Alan F. Scott
Alan F. Scott Johns Hopkins University
Mary L. Marazita
Mary L. Marazita University of Pittsburgh
Nadia N. Hansel
Nadia N. Hansel Johns Hopkins University
Ethylin Wang Jabs
Ethylin Wang Jabs Icahn School of Medicine at Mount Sinai
James G. Wilson
James G. Wilson University of Mississippi Medical Center
Lisa R. Yanek
Lisa R. Yanek Johns Hopkins University School of Medicine

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